Staff Investigator - Turkson
Staff Investigator - Turkson
批准号:
8724385
负责人:
MICHELE CARBONE
金额:
$0.67万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AffectAnimal ModelAntineoplastic AgentsApplications GrantsAreaBasic ScienceBiologicalBiological FactorsBiological ModelsBudgetsCancer BiologyCancer CenterCancer Center Support GrantCell physiologyCellsChemistryClinicalClinical ResearchClinical TrialsCollaborationsCommunity Health EducationDevelopmentDiagnosticDoctor of PhilosophyDrug Discovery GroupsEmerging TechnologiesEquipmentEvaluationExtramural ActivitiesFacultyFloridaFosteringFundingGenesGoalsGrantHawaiiHumanIndigenousJointsLeadLeadershipLegal patentLibrariesMalignant NeoplasmsMalignant neoplasm of ovaryMalignant neoplasm of prostateMarinesMediatingMissionModalityMolecularOrganismOutcomePaperPatientsPeer ReviewPersonalityPersonsPharmaceutical ChemistryPlayPreclinical Drug EvaluationProteinsPublicationsPublishingRecording of previous eventsRecruitment ActivityResearchResearch ActivityResearch PersonnelResearch Project GrantsRoleScientistShapesStat3 proteinStimulusTherapeuticTherapeutic InterventionTranslational ResearchTranslationsUniversitiesValidationWorkassay developmentbench to bedsidecellular targetingcombinatorialdesigndisorder riskdrug developmentdrug discoveryexperiencein vivoinhibitor/antagonistinterestmalignant breast neoplasmmembernovelpreclinical studyprogramsresponsescreeningsmall moleculewillingness
中文摘要
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英文摘要
The University of Hawaii Cancer Center is requesting partial support for two (2) Staff Investigators, each of whom will focus on a strategic research/clinical area of major interest to the Cancer Center.
James Turkson, PhD, a recent recruit to the University of Hawaii Cancer Center from the Moffit Cancer Center and the University of Central Florida, will lead the creation of a robust drug development initiative within the Cancer Biology Program with the goal of building scientific collaborations focused on translational research involving Cancer Center members from both the basic science programs and our clinical partners. Dr. Turkson has extensive experience in drug development having spent more than a decade designing and evaluating small molecule inhibitors of the signaling transducer and activator of transcription-3 (STAT-3) protein. STAT-3 mediates the expression of a variety of genes in response to cell stimuli and plays a key role in many cellular processes, including the initiation and progression of various human cancers. Dr. Turkson has published over 50 peer reviewed papers and co-authored 4 issued patents and 8 provisional and pending patents in the field.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Influence of germline mutations on susceptibility to environmental carcinogens
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批准号:10212390
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项目类别:
-
资助金额:$62.61万
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财政年份:2019
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负责人:MICHELE CARBONE
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依托单位:
Mechanisms of BAP1 activity in human cancer development
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批准号:9888180
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项目类别:
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资助金额:$41.35万
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财政年份:2019
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负责人:MICHELE CARBONE
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依托单位:
Mechanisms of BAP1 activity in human cancer development
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批准号:10528437
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项目类别:
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资助金额:$44.46万
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财政年份:2019
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负责人:MICHELE CARBONE
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依托单位:
Mechanisms of BAP1 activity in human cancer development
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批准号:10304905
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项目类别:
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资助金额:$44.33万
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财政年份:2019
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负责人:MICHELE CARBONE
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依托单位:
Germline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early Detection
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批准号:9294995
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项目类别:
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资助金额:$35.23万
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财政年份:2015
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负责人:MICHELE CARBONE
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依托单位:
Germline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early Detection
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批准号:9105728
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项目类别:
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资助金额:$35.23万
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财政年份:2015
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负责人:MICHELE CARBONE
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依托单位:
Cancer Biology
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批准号:8369385
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项目类别:
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资助金额:$2.33万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Biostatistics and Informatics Shared Resource
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批准号:8369399
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项目类别:
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资助金额:$11.35万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Pathlogy Shared Resource
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批准号:8369398
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项目类别:
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资助金额:$4.83万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Cancer Prevention and Control
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批准号:8369387
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项目类别:
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资助金额:$0.84万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Animal Carcinogenesis Core - Developmental Funds
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批准号:8369407
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项目类别:
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资助金额:$6.17万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Staff Investigator - Turkson
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批准号:8369403
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项目类别:
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资助金额:$1.63万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Cancer Epidemiology
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批准号:8369386
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项目类别:
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资助金额:$1.0万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Planning and Evaluation
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批准号:8369406
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项目类别:
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资助金额:$3.02万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Genomics Shared Resource
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批准号:8369395
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项目类别:
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资助金额:$3.75万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Analytical Biochemistry Shared Resource
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批准号:8369394
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项目类别:
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资助金额:$10.69万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Clinical and Translational Research Services Shared Resource
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批准号:8369400
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项目类别:
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资助金额:$10.63万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Senior Leadership
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批准号:8369405
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项目类别:
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资助金额:$16.6万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Microscopy and Imaging Shared Resource
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批准号:8369396
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项目类别:
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资助金额:$2.17万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
Protocol Review and Monitoring System
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批准号:8369401
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项目类别:
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资助金额:$1.07万
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财政年份:2012
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负责人:MICHELE CARBONE
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依托单位:
海外基金