Efficiency of Various Devices and Theories to Collect Nanoparticles Directly onto

直接收集纳米颗粒的各种设备和理论的效率

• 批准号: 9282836
• 负责人: Candace SuJung Tsai
• 金额: $ 6.48万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-02 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9282836
• 关键词: Efficiency; Various; Devices; Theories; Collect

DESCRIPTION (provided by applicant): Transmission electron microscope (TEM) is a very useful technique for evaluating nanoparticle morphology, for elemental analysis, and for particle counting and sizing. This technique has recently become a required tool to characterize exposure to airborne nanoparticles. The specific aim of this proposed research is to compare the available methods using TEM diffusive sampler (TDS), electrostatic precipitation sampler (EPS) and thermophoretic sampler (TPS) for directly depositing airborne engineered nanoparticles (ENPs) onto grids for material characterization. Research objectives include: comparison of size distributions, deposition uniformity and the ease of use. Test nanoparticle aerosols will be generated and samples will be collected side-by-side with three devices using each method, along with the NanoScan SMPS (TSI Model 3910, 10-420 nm) and Optical Particle Counter (OPC) (TSI Model 3330, 300 nm- 10 �m) to record the particle concentration. Experiments will be performed in the Birck Nanotechnology cleanroom laboratory at Purdue University. This research will test the following hypotheses: (1) Basic aerosol theory can be used to predict particle collection onto TEM grids; (2)TPS is more efficient than TDS and EPS for collecting particles less than 200 nm directly onto a TEM grid, EPS is more efficient than TPS and TDS for collecting particles from 200 nm - 10 �m, and none of the techniques are efficient at collecting particles larger than 1 �m; and (3) Nanoparticles collected by all three mechanisms are randomly distributed across a grid surface. The results from this research will provide informative technical results to develop the adequate use of samplers for collecting nanoparticles. In addition, the results will provide the input for further modifications to existin samplers or the development of a newly-designed sampler which can provide better performance for future research.

描述（由申请人提供）：透射电子显微镜（TEM）是一种非常有用的技术，可用于评估纳米颗粒形态、元素分析以及颗粒计数和尺寸确定。该技术最近已成为表征空气中纳米颗粒暴露的必要工具。这项研究的具体目的是比较现有的方法，使用TEM扩散采样器（TDS），静电沉淀采样器（EPS）和热泳采样器（TPS）直接沉积到网格上的材料表征的空气中的工程纳米粒子（ENPs）。研究目标包括：尺寸分布，沉积均匀性和易用性的比较。将产生测试纳米颗粒气溶胶，并使用每种方法用三个装置并排收集样品，沿着使用NanoScan SMPS（TSI型号3910，10-420 nm）和光学颗粒计数器（OPC）（TSI型号3330，300 nm- 10 μ m）记录颗粒浓度。实验将在普渡大学的Birck纳米技术洁净室实验室进行。 本研究将验证以下假设：（1）基本气溶胶理论可以用来预测粒子在TEM网格上的收集;（2）TPS比TDS和EPS更有效地将小于200 nm的颗粒直接收集到TEM网格上，EPS比TPS和TDS更有效地收集200 nm - 10 μ m的颗粒，没有一种技术能有效地收集大于1 μ m的颗粒;（3）通过所有三种机制收集的纳米颗粒随机分布在网格表面上。 这项研究的结果将提供信息丰富的技术成果，以开发适当使用采样器收集纳米粒子。此外，研究结果将为进一步修改Eschertin采样器或开发新设计的采样器提供输入，该采样器可以为未来的研究提供更好的性能。