Graduate and Postdoctoral Training in Toxicology

毒理学研究生和博士后培训

• 批准号: 8500272
• 负责人: GARY W MILLER
• 金额: $ 44.09万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8500272
• 关键词: Toxicology; post-doctoral training

DESCRIPTION (provided by applicant) The primary purpose of this broadly based multidisciplinary toxicology and environmental health sciences training program is to prepare trainees for biomedical research careers in schools of medicine, public health, and pharmacy, and in governmental or industrial laboratories with a sound knowledge in environmental health and toxicology. The areas of research emphasis represented by the 22 training faculty include neurotoxicity and neurodegenerative disease, mechanisms of cell death, oxidative DNA damage and repair, and environmental assessment and epidemiology. The 22 members of the training faculty have an established record of success in research training and are currently funded by a total of over $10,000,000 in federal grants with a third of that being from NIEHS. Several scientists from the Centers for Disease Control, including the Agency for Toxic Substances and Diseases Registry, also participate in the training of students through guest lectures and collaborative research. The most important component of training is laboratory research, first as a series of three research rotations, then in the dissertation laboratory. This training is complemented by core courses in toxicology, biochemistry, pharmacology, cell biology, molecular biology, and biostatistics, and advanced courses in toxicology specialty areas, seminar courses, and journal clubs. The program is designed to support six students and three postdoctoral fellows each year from a total eligible population of about 24 students and 30 postdoctoral fellows. The student who completes the pre-doctoral Training Program will have acquired broad familiarity with toxicology and environmental health, knowledge in depth in the area of dissertation research, the ability to search, read critically and report on the literature of the biomedical sciences, mastery of a variety of laboratory techniques useful in modern biomedical research, skill in planning and executing a research project, ability to write clear, accurate scientific reports for publication, and ability to present effectively the results of research. The postdoctoral fellow who completes the Training Program will have gained extensive experience in cutting edge toxicology research, and should have submitted an individual NRSA application to gain grant writing experience to aid in the transition into an independent research position. BACKGROUND This is the first competitive renewal for this Training Program submitted from Emory University. The program is administratively positioned within the Molecular Pharmacology Program (MSP) within the Division of Biological and Biomedical Sciences (DBBS). The goal of the program is to produce broadly trained, competitive scientists oriented towards productive careers related to the toxicological and environmental health sciences. The program is directed by Dr. Gary Miller and co-directed by Dr. Dean Jones. During the first four years of funding, the program has recruited its first classes of pre-doctoral students (total of 12) and postdoctoral fellows (total of 8), expanded the number of participating faculty mentors from 13 to 20, developed a toxicology curriculum within MSP and began the process of establishing the procedures by which students are selected and mentored.

描述（由申请人提供） 这个基础广泛的多学科毒理学和环境健康科学培训计划的主要目的是为医学，公共卫生和药学学校的生物医学研究职业做好准备，并在政府或工业实验室中具有良好的环境健康和毒理学知识。由22个培训教师代表的研究重点领域包括神经毒性和神经退行性疾病，细胞死亡机制，氧化DNA损伤和修复，以及环境评估和流行病学。培训学院的22名成员在研究培训方面取得了成功，目前获得了超过1000万美元的联邦赠款，其中三分之一来自NIEHS。 来自疾病控制中心，包括有毒物质和疾病登记署的几位科学家也通过客座讲座和合作研究参与学生培训。培训的最重要组成部分是实验室研究，首先作为一系列的三个研究轮换，然后在论文实验室。该培训由毒理学，生物化学，药理学，细胞生物学，分子生物学和生物统计学的核心课程以及毒理学专业领域的高级课程，研讨会课程和期刊俱乐部补充。 该计划旨在支持六名学生和三名博士后研究员，每年从约24名学生和30名博士后研究员的总合格人口。完成博士前培训计划的学生将广泛熟悉毒理学和环境卫生，深入了解论文研究领域，能够搜索，批判性阅读和报告生物医学科学文献，掌握各种现代生物医学研究中有用的实验室技术，规划和执行研究项目的技能，能够写清楚，发表准确的科学报告，并有能力有效地提出研究结果。完成培训计划的博士后研究员将在尖端毒理学研究方面获得丰富的经验，并应提交个人NRSA申请以获得资助写作经验，以帮助过渡到独立的研究职位。 背景 这是埃默里大学提交的第一份培训计划的竞争性续约。 该计划在行政上位于生物和生物医学科学部（DBBS）的分子药理学计划（MSP）内。 该计划的目标是产生广泛培训，有竞争力的科学家，面向与毒理学和环境健康科学相关的生产性职业。该计划是由加里米勒博士和共同导演迪恩琼斯博士。 在资助的前四年，该计划招募了第一类博士前学生（共12名）和博士后研究员（共8名），将参与教师导师的数量从13人扩大到20人，在MSP内开发了毒理学课程，并开始建立学生选择和指导程序的过程。