Refinement and Expansion of the Palliative Care Research Cooperative Group (PCRC)

姑息治疗研究合作小组 (PCRC) 的完善和扩大

基本信息

  • 批准号:
    8926710
  • 负责人:
  • 金额:
    $ 183.94万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-09-28 至 2016-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): In 2010, the Palliative Care Research Cooperative Group (PCRC) was developed as a national collaborative research network to become the scalable, supportive structure so critically needed for the conduct of high quality clinical trials Work proposed under the current grant will build on the accomplishments achieved during the initial NINR funding for the PCRC (UC4NR012584). The overarching objective of this U24 grant application is to amplify the role of the PCRC as a national resource for efficient conduct of high quality, collaborative, multisite, palliative care and end-of-life (PCEOL) research by leveraging and building upon the prior NINR investment and accomplishments of the PCRC to date. The steps planned for further PCRC development will enable it to: (1) support research and develop expertise in understudied PCEOL areas such as caregiver and bio-behavioral research; (2) facilitate efficient and expeditious conduct of important, cutting-edge studies that require large samples and multiple sites; (3) prepare future researchers to utilize and sustain the enterprise, while continuing to build the PCEOL evidence base, and; (4) describe, quantify, and understand the risks, issues, and impact of life-limiting disease on multiple relevant outcomes including health outcomes for patients and caregivers and bio-behavioral interventions and outcomes. Specifically, we propose to rapidly increase the capacity of the PCRC to develop and conduct a diversified portfolio of high quality research studies that are responsive to key gaps in the scientific knowledge. We will achieve these goals through the following specific aims: (1) develop a national research capacity for collaborative, multisite, PCEOL research in a way that maximizes the quality and efficiency of research and the effectiveness of cooperative groups; and (2) provide integrated support for PCEOL research, specifically, for the conduct, analysis, and dissemination of clinically meaningful, high-quality, efficient, patient-centered, multisite studies. The combined result of achieving these aims will be a highly efficient, adaptive, and standardized system to advance prioritized, innovative, rigorously designed and performed, studies in PCEOL research, with a particular emphasis on clinical trials requiring multiple recruitment sites. RELEVANCE: The Palliative Care Research Cooperative Group (PCRC) addresses national research priorities in palliative care and end-of-life (PCEOL) through enhancing efficient conduct and dissemination of high-quality, collaborative, multisite, PCEOL research. The result of achieving the PCRC aims will be a highly efficient, adaptive, and standardized system to advance prioritized, innovative, rigorously designed and performed PCEOL studies that will ultimately enhance and improve care for people with serious and life limiting illnesses.
描述(由申请人提供):在2010年,姑息治疗研究合作组(PCRC)被开发为一个国家合作研究网络,成为可扩展的,支持性的结构,因此迫切需要进行高质量的临床试验根据目前的拨款工作提出将建立在最初的NINR资助PCRC(UC 4 NR 012584)期间取得的成就。这U24赠款申请的首要目标是扩大PCRC作为国家资源的作用,以有效地进行高 质量,协作,多站点,姑息治疗和临终关怀(PCEOL)研究,利用和建立在先前的NINR投资和PCRC迄今取得的成就。计划进一步发展PCRC的步骤将使其能够:(1)支持研究和发展未充分研究的PCEOL领域的专业知识,如护理人员和生物行为研究;(2)促进有效和迅速地进行需要大样本和多个地点的重要尖端研究;(3)为未来的研究人员利用和维持企业做好准备,同时继续建立PCEOL证据库;(4)描述、量化和理解生命限制性疾病的风险、问题和对多种相关结果的影响,包括患者和护理人员的健康结果以及生物行为干预和结果。具体而言,我们建议迅速提高PCRC的能力,以开发和开展多样化的高质量研究,以应对科学知识的关键差距。我们将通过以下具体目标实现这些目标:(1)以最大限度地提高研究质量和效率以及合作小组的有效性的方式,发展国家协作、多地点、PCEOL研究的研究能力;和(2)为PCEOL研究提供综合支持,特别是对临床上有意义的、高质量的、有效的、以患者为中心的、多中心研究。实现这些目标的综合结果将是一个高效,自适应和标准化的系统,以推进PCEOL研究中的优先,创新,严格设计和执行的研究,特别强调需要多个招募地点的临床试验。 相关性:姑息治疗研究合作组(PCRC)通过提高高质量,协作,多地点,PCEOL研究的有效进行和传播,解决姑息治疗和生命终结(PCEOL)的国家研究重点。实现PCRC目标的结果将是一个高效,自适应和标准化的系统,以推进优先,创新,严格设计和执行PCEOL研究,最终将加强和改善对严重和生命限制性疾病患者的护理。

项目成果

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JEAN S KUTNER其他文献

JEAN S KUTNER的其他文献

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{{ truncateString('JEAN S KUTNER', 18)}}的其他基金

Diversifying and Strengthening Dementia Palliative Care Clinical Trials
多样化和加强痴呆症姑息治疗临床试验
  • 批准号:
    10409239
  • 财政年份:
    2022
  • 资助金额:
    $ 183.94万
  • 项目类别:
Diversifying and Strengthening Dementia Palliative Care Clinical Trials
多样化和加强痴呆症姑息治疗临床试验
  • 批准号:
    10626045
  • 财政年份:
    2022
  • 资助金额:
    $ 183.94万
  • 项目类别:
Multidisciplinary Research Training in Palliative Care
姑息治疗的多学科研究培训
  • 批准号:
    8666995
  • 财政年份:
    2014
  • 资助金额:
    $ 183.94万
  • 项目类别:
Multidisciplinary Research Training in Palliative Care
姑息治疗的多学科研究培训
  • 批准号:
    9922826
  • 财政年份:
    2014
  • 资助金额:
    $ 183.94万
  • 项目类别:
Palliative Care Research Cooperative Group (PCRC): Refinement and Expansion
姑息治疗研究合作小组 (PCRC):细化和扩展
  • 批准号:
    10331658
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
Engaging patients, family members and caregivers in end-of-life and palliative care (EOLPC) research: Addressing the bioethical challenges
让患者、家庭成员和护理人员参与临终关怀和姑息治疗 (EOLPC) 研究:应对生物伦理​​挑战
  • 批准号:
    9927885
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
Palliative Care Research Cooperative Group (PCRC): Refinement and Expansion
姑息治疗研究合作小组 (PCRC):细化和扩展
  • 批准号:
    10207778
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center
姑息治疗研究合作小组 (PCRC):项目协调中心
  • 批准号:
    10207779
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
Refinement and Expansion of the Palliative Care Research Cooperative Group (PCRC)
姑息治疗研究合作小组 (PCRC) 的完善和扩大
  • 批准号:
    9108177
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center
姑息治疗研究合作小组 (PCRC):项目协调中心
  • 批准号:
    10438796
  • 财政年份:
    2013
  • 资助金额:
    $ 183.94万
  • 项目类别:
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