Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center

项目摘要/摘要 该U2C应用程序的主要目标是提高姑息治疗的工作效率和影响 研究合作小组(PCRC)，促进进行高质量、有效的临床研究，以及 在进行多点临床试验方面扩大姑息治疗研究人员的数量和专业知识。在……里面 为了追求这些总体目标和目的，项目协调中心(PCC)是以下两个中心之一 PCRC致力于改进和增强可复制和可扩展的基础设施、流程、工具和方法， 包括评估指标，以支持高效和有效的协作群体功能。公众投诉委员会的特定 目标是：(1)为PCRC提供组织基础设施，包括有效的行政、财务、 监管和数据管理职能，以及跟踪和监测PCRC的业绩和 成果；(2)在合作小组职能方面管理PCRC的日常运作和 流程，同时开发可复制的、标准化的、有质量保证的操作方法和工具；(3) 作为PCRC核心、中心、调查人员和站点的中央协调中心，负责 通信、联络活动、行政支助以及相关努力和职能的整合；以及 (4)通过支持调查人员和在调查人员中发展研究能力 在整个过程中，从研究开发到研究进行，并在完成后，转移 将已取消身份的数据存入PCRC数据储存库。通过新的或扩展的计划，例如支持 调查人员将遵守新的NIH单一IRB要求进行多站点研究、跟踪和支持 研究人员遵守新的和不断变化的临床试验要求(与研究人员合作 发展中心)，并支持招募和保留不同的研究人群，PCC 为预委会及其调查人员提供高效率和有效的支持结构。

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), facilitating the conduct of high-quality, effective clinical research, and expanding the number and expertise of palliative care researchers in conducting multi-site clinical trials. In pursuit of these overall goals and objectives, the Project Coordinating Center (PCC), one of two Centers within the PCRC, strives to refine and enhance replicable and scalable infrastructure, processes, tools, and methods, including evaluative metrics, to support efficient and effective cooperative group function. The PCC's specific aims are to: (1) provide organizational infrastructure to the PCRC, including efficient administrative, financial, regulatory, and data management functions as well as tracking and monitoring of PCRC performance and outcomes; (2) manage day-to-day operations of the PCRC with respect to cooperative group functions and processes, while developing replicable, standardized, quality-assured, operational methods and tools; (3) serve as a central coordinating hub for PCRC Cores, Centers, investigators and sites, with responsibility for communications, liaison activities, administrative support and integration of relevant efforts and functions; and (4) develop research capacity at PCRC sites and among PCRC investigators by supporting investigators and sites throughout the continuum from study development through study conduct and, when completed, transfer of de-identified data to the PCRC Data Repository. Through new or expanded initiatives, such as supporting investigators to comply with new NIH single IRB requirements for multi-site studies, tracking and supporting investigators' compliance with new and evolving clinical trial requirements (in partnership with the Investigator Development Center), and supporting recruitment and retention of diverse study populations, the PCC provides an efficient and effective support structure for the PCRC and its investigators.