Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center

姑息治疗研究合作小组 (PCRC)：项目协调中心

• 批准号: 10207779
• 负责人: JEAN S KUTNER
• 金额: $ 79.42万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-28 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10207779
• 关键词: Achievement; Address; Advisory Committees; Award; Businesses; Caregiver research; Childhood; Clinical Research; Clinical Trials; Collaborations; Communication; Data; Development; Economically Deprived Population; Funding; Goals; Grant; Informatics; Infrastructure; Institutional Review Boards; Intention; Investments; Logistics; Marketing; Measurement; Methodological Studies; Methods; Monitor; Multi-Institutional Clinical Trial; Occupational activity of managing finances; Outcome; Palliative Care; Performance; Phase; Population; Principal Investigator; Process; Productivity; Reporting; Research; Research Personnel; Research Support; Resources; Science; Site; Special Population; Standardization; Structure; Support Groups; Training; Underrepresented Minority; United States National Institutes of Health; data de-identification; data management; data repository; multiple chronic conditions; operation; recruit; statistics; study population; success; tool

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), facilitating the conduct of high-quality, effective clinical research, and expanding the number and expertise of palliative care researchers in conducting multi-site clinical trials. In pursuit of these overall goals and objectives, the Project Coordinating Center (PCC), one of two Centers within the PCRC, strives to refine and enhance replicable and scalable infrastructure, processes, tools, and methods, including evaluative metrics, to support efficient and effective cooperative group function. The PCC's specific aims are to: (1) provide organizational infrastructure to the PCRC, including efficient administrative, financial, regulatory, and data management functions as well as tracking and monitoring of PCRC performance and outcomes; (2) manage day-to-day operations of the PCRC with respect to cooperative group functions and processes, while developing replicable, standardized, quality-assured, operational methods and tools; (3) serve as a central coordinating hub for PCRC Cores, Centers, investigators and sites, with responsibility for communications, liaison activities, administrative support and integration of relevant efforts and functions; and (4) develop research capacity at PCRC sites and among PCRC investigators by supporting investigators and sites throughout the continuum from study development through study conduct and, when completed, transfer of de-identified data to the PCRC Data Repository. Through new or expanded initiatives, such as supporting investigators to comply with new NIH single IRB requirements for multi-site studies, tracking and supporting investigators' compliance with new and evolving clinical trial requirements (in partnership with the Investigator Development Center), and supporting recruitment and retention of diverse study populations, the PCC provides an efficient and effective support structure for the PCRC and its investigators.

项目总结/摘要 此U2 C应用程序的主要目标是提高姑息治疗的生产率和影响力 研究合作组（PCRC），促进高质量，有效的临床研究的进行， 扩大姑息治疗研究人员的数量和专业知识，进行多点临床试验。在 为了实现这些总体目标和目的，项目协调中心（PCC）是 PCRC致力于改进和增强可复制和可扩展的基础设施、流程、工具和方法， 包括评价指标，以支持高效和有效的合作小组职能。PCC的具体 目标是：（1）为PCRC提供组织基础设施，包括有效的行政，财务， 监管和数据管理职能，以及跟踪和监控PCRC绩效， （2）管理PCRC在合作小组职能方面的日常运作， （c）在制定可复制、标准化、有质量保证的业务方法和工具的同时， 作为PCRC核心、中心、研究者和研究中心的中央协调中心，负责 沟通、联络活动、行政支助以及相关工作和职能的整合; (4)通过支持研究者，发展PCRC研究中心和PCRC研究者的研究能力， 研究中心从研究开发到研究实施的整个过程，以及研究完成后的转移 将去识别化的数据发送到PCRC数据存储库。通过新的或扩大的举措，如支持 研究者遵守NIH单一IRB对多中心研究、跟踪和支持的新要求 研究者对新的和不断发展的临床试验要求的依从性（与研究者合作 发展中心），并支持招募和保留不同的研究人群，PCC 为投诉委员会及其调查人员提供有效率和有成效的支援架构。