Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center

姑息治疗研究合作小组 (PCRC)：项目协调中心

• 批准号: 10438796
• 负责人: JEAN S KUTNER
• 金额: $ 82.56万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-28 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10438796
• 关键词: Achievement; Address; Advisory Committees; Award; Businesses; Caregiver research; Childhood; Clinical Research; Clinical Trials; Collaborations; Communication; Data; Development; Economically Deprived Population; Funding; Goals; Grant; Informatics; Infrastructure; Institutional Review Boards; Intention; Investments; Logistics; Marketing; Measurement; Methodological Studies; Methods; Monitor; Multi-Institutional Clinical Trial; Occupational activity of managing finances; Outcome; Palliative Care; Performance; Phase; Population; Principal Investigator; Process; Productivity; Reporting; Research; Research Personnel; Research Support; Resources; Science; Site; Special Population; Standardization; Structure; Support Groups; Training; Underrepresented Minority; United States National Institutes of Health; data de-identification; data management; data repository; multiple chronic conditions; operation; recruit; statistics; study population; success; tool

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), facilitating the conduct of high-quality, effective clinical research, and expanding the number and expertise of palliative care researchers in conducting multi-site clinical trials. In pursuit of these overall goals and objectives, the Project Coordinating Center (PCC), one of two Centers within the PCRC, strives to refine and enhance replicable and scalable infrastructure, processes, tools, and methods, including evaluative metrics, to support efficient and effective cooperative group function. The PCC's specific aims are to: (1) provide organizational infrastructure to the PCRC, including efficient administrative, financial, regulatory, and data management functions as well as tracking and monitoring of PCRC performance and outcomes; (2) manage day-to-day operations of the PCRC with respect to cooperative group functions and processes, while developing replicable, standardized, quality-assured, operational methods and tools; (3) serve as a central coordinating hub for PCRC Cores, Centers, investigators and sites, with responsibility for communications, liaison activities, administrative support and integration of relevant efforts and functions; and (4) develop research capacity at PCRC sites and among PCRC investigators by supporting investigators and sites throughout the continuum from study development through study conduct and, when completed, transfer of de-identified data to the PCRC Data Repository. Through new or expanded initiatives, such as supporting investigators to comply with new NIH single IRB requirements for multi-site studies, tracking and supporting investigators' compliance with new and evolving clinical trial requirements (in partnership with the Investigator Development Center), and supporting recruitment and retention of diverse study populations, the PCC provides an efficient and effective support structure for the PCRC and its investigators.

项目概要/摘要 此 U2C 应用程序的主要目标是提高姑息治疗的生产力和影响 研究合作小组（PCRC），促进高质量、有效的临床研究的进行，以及 扩大姑息治疗研究人员的数量和专业知识，以进行多地点临床试验。在 为了实现这些总体目标和目标，项目协调中心（PCC）是内部两个中心之一 PCRC，致力于完善和增强可复制和可扩展的基础设施、流程、工具和方法， 包括评估指标，以支持高效且有效的合作团队职能。 PCC的具体 目标是：(1) 为 PCRC 提供组织基础设施，包括高效的行政、财务、 监管和数据管理功能以及 PCRC 性能的跟踪和监控 结果； (2) 管理PCRC有关合作团体职能的日常运作； 流程，同时开发可复制、标准化、有质量保证的操作方法和工具； (3) 作为 PCRC 核心、中心、研究者和站点的中央协调中心，负责 沟通、联络活动、行政支持以及相关工作和职能的整合；和 (4) 通过支持研究者和 PCRC 站点以及 PCRC 研究者的研究能力 从研究开发到研究实施以及完成后的转移的整个过程中的站点 将去识别化数据传输至 PCRC 数据库。通过新的或扩大的举措，例如支持 研究人员遵守新的 NIH 单一 IRB 多中心研究、跟踪和支持要求 研究者遵守新的和不断变化的临床试验要求（与研究者合作） 发展中心），并支持招募和保留不同的研究人群，PCC 为 PCRC 及其调查人员提供高效且有效的支持结构。