Optimization of Dialysis Fistula Maturation via Vascular Ultrasound Elasticity an
通过血管超声弹性和优化透析瘘成熟
基本信息
- 批准号:8732651
- 负责人:
- 金额:$ 18.36万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-09-15 至 2016-08-31
- 项目状态:已结题
- 来源:
- 关键词:AlgorithmsAnatomyAngioplastyArchitectureArteriesArteriovenous fistulaBloodBlood VesselsBlood flowCaliberCardiacCathetersClinicalClinical ResearchClinical TrialsCommunicationComplicationComputer softwareDataDiagnosticDiagnostic ProcedureDialysis procedureEarly InterventionElasticityFailureFistulaFoundationsFrequenciesFutureGelatinGeometryGoalsGrantGuidelinesHealth Services AccessibilityHemodialysisImageImaging DeviceIn VitroIncidenceInterventionInvestigationKidneyLinkLongevityManufacturer NameMeasurementMeasuresMechanicsMedicalMedicineMethodsMetricMulti-Institutional Clinical TrialNatureOperative Surgical ProceduresOutcomePatientsPhysiologicalPilot ProjectsPostoperative PeriodPrevalenceProceduresPropertyProtocols documentationPublic DomainsPulsatile FlowRadioResearchResearch PersonnelResolutionRiskSamplingSecond Look SurgerySoftware ToolsStimulusStressStudy SubjectSystemTechniquesTimeTissuesTranslatingUltrasonographyUncertaintyUnited States National Institutes of HealthVascular remodelingVeinsVelocimetriesVenousabstractingbasecostdigital imagingelastographyfile formatfluid flowhemodynamicsimage processingimprovedin vivointerestmeetingsparticlepublic health relevanceresearch studysignal processingsuccesstool
项目摘要
DESCRIPTION (provided by applicant): Optimization of Dialysis Fistula Maturation via Vascular Ultrasound Elasticity and Shear Rate Imaging R21: NIH PI: William Weitzel, MD Co-I: Albert Shih, PHD, Grant Kruger, Matthew Leavitt, Peter Henke Abstract Vascular access is crucial to the treatments necessary for hemodialysis patients. Due to their reliability, longevity,
and lower complication rates, autogenous arteriovenous fistulas - surgically created connections between arteries and veins - have become increasingly prominent over other forms of vascular access. However, the uncertainty associated with fistula maturation has caused undue cost, risk, and stress to patients already undergoing significant medical procedures. Currently no system exists to directly and noninvasively measure the underlying causes of vascular remodeling during fistula maturation. We propose to build an ultrasound software toolbox - referred to as the vascular ultrasound elastography and shear rate (VUESR) imaging - that has unprecedented temporal and spatial resolution to identify vessel wall edges and measure vessel size, elastic properties, and blood-wall shear rate during the cardiac cycles. After validating thi tool both in vitro (through phantom studies on simple and realistic fistula geometries) and in vivo
(a pilot study conducted on a small sample of hemodialysis patients pre- and post-fistula creation), we plan to release the software necessary for this technique available in the public domain as an open platform tool for researchers. This software tool will be useful for pre-operative planning and post-operative assessment to guide decisions for angioplasty and surgical revision. Given the ubiquity and noninvasive nature of ultrasound imaging and the broad open access with which we plan to release this tool, this proposal can radically accelerate safe and effective ultrasound diagnostic methods for fistula optimization.
描述(由申请人提供):通过血管超声弹性和剪切率成像优化透析瘘成熟R21: NIH PI: William Weitzel, MD Co-I: Albert Shih, PHD, Grant Kruger, Matthew Leavitt, Peter Henke摘要血管通路对于血液透析患者的必要治疗至关重要。由于它们的可靠性和寿命,
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
An Open-Source Ultrasound Software for Diagnosis of Fistula Maturation.
- DOI:10.1097/mat.0000000000000590
- 发表时间:2018
- 期刊:
- 影响因子:0
- 作者:Belmont B;Park DW;Weitzel WF;Shih AJ
- 通讯作者:Shih AJ
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
William F Weitzel其他文献
William F Weitzel的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('William F Weitzel', 18)}}的其他基金
Point of Care Elastographic Sonoangiography (eSA)
护理点弹性超声血管造影 (eSA)
- 批准号:
9768247 - 财政年份:2017
- 资助金额:
$ 18.36万 - 项目类别:
Point of Care Elastographic Sonoangiography (eSA)
护理点弹性超声血管造影 (eSA)
- 批准号:
9393446 - 财政年份:2017
- 资助金额:
$ 18.36万 - 项目类别:
Optimization of Dialysis Fistula Maturation via Vascular Ultrasound Elasticity an
通过血管超声弹性和优化透析瘘成熟
- 批准号:
8621267 - 财政年份:2013
- 资助金额:
$ 18.36万 - 项目类别:
Point-of-Care Carotid Ultrasound and Cardiovascular Risk Assessment Device
护理点颈动脉超声和心血管风险评估装置
- 批准号:
8455104 - 财政年份:2013
- 资助金额:
$ 18.36万 - 项目类别:
Telehealth-Enabled Ultrasound-Bioimpedance Viscoelastographic Edema Monitoring
支持远程医疗的超声生物阻抗粘弹性成像水肿监测
- 批准号:
8795695 - 财政年份:2012
- 资助金额:
$ 18.36万 - 项目类别:
Doppler Window for Low-Cost High-Performance Vascular Imaging
用于低成本高性能血管成像的多普勒窗口
- 批准号:
8253138 - 财政年份:2012
- 资助金额:
$ 18.36万 - 项目类别:
Telehealth-Enabled Ultrasound-Bioimpedance Viscoelastographic Edema Monitoring
支持远程医疗的超声生物阻抗粘弹性成像水肿监测
- 批准号:
8330416 - 财政年份:2012
- 资助金额:
$ 18.36万 - 项目类别:
Telehealth-Enabled Ultrasound-Bioimpedance Viscoelastographic Edema Monitoring
支持远程医疗的超声生物阻抗粘弹性成像水肿监测
- 批准号:
8460425 - 财政年份:2012
- 资助金额:
$ 18.36万 - 项目类别:
Magnetic Drive Mechanism for VF Doppler Smart Sensor
VF多普勒智能传感器的磁力驱动机构
- 批准号:
8199261 - 财政年份:2011
- 资助金额:
$ 18.36万 - 项目类别:
VF Doppler Smart Sensor for Dialysis and Vascular Applications
适用于透析和血管应用的 VF 多普勒智能传感器
- 批准号:
7833128 - 财政年份:2009
- 资助金额:
$ 18.36万 - 项目类别:
相似海外基金
Linking Epidermis and Mesophyll Signalling. Anatomy and Impact in Photosynthesis.
连接表皮和叶肉信号传导。
- 批准号:
EP/Z000882/1 - 财政年份:2024
- 资助金额:
$ 18.36万 - 项目类别:
Fellowship
Digging Deeper with AI: Canada-UK-US Partnership for Next-generation Plant Root Anatomy Segmentation
利用人工智能进行更深入的挖掘:加拿大、英国、美国合作开发下一代植物根部解剖分割
- 批准号:
BB/Y513908/1 - 财政年份:2024
- 资助金额:
$ 18.36万 - 项目类别:
Research Grant
Simultaneous development of direct-view and video laryngoscopes based on the anatomy and physiology of the newborn
根据新生儿解剖生理同步开发直视喉镜和视频喉镜
- 批准号:
23K11917 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Genetics of Extreme Phenotypes of OSA and Associated Upper Airway Anatomy
OSA 极端表型的遗传学及相关上呼吸道解剖学
- 批准号:
10555809 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
computational models and analysis of the retinal anatomy and potentially physiology
视网膜解剖学和潜在生理学的计算模型和分析
- 批准号:
2825967 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Studentship
Computational comparative anatomy: Translating between species in neuroscience
计算比较解剖学:神经科学中物种之间的翻译
- 批准号:
BB/X013227/1 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Research Grant
Doctoral Dissertation Research: Social and ecological influences on brain anatomy
博士论文研究:社会和生态对大脑解剖学的影响
- 批准号:
2235348 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Standard Grant
Development of a novel visualization, labeling, communication and tracking engine for human anatomy.
开发一种新颖的人体解剖学可视化、标签、通信和跟踪引擎。
- 批准号:
10761060 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Understanding the functional anatomy of nociceptive spinal output neurons
了解伤害性脊髓输出神经元的功能解剖结构
- 批准号:
10751126 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
The Anatomy of Online Reviews: Evidence from the Steam Store
在线评论剖析:来自 Steam 商店的证据
- 批准号:
2872725 - 财政年份:2023
- 资助金额:
$ 18.36万 - 项目类别:
Studentship