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DESCRIPTION (provided by applicant): The Stanford OHNS Core Center is organized into two Core facilities: Core I - Imaging Core and Core II - Inner Ear Physiology Core. Both cores serve to facilitate interdisciplinary collaborative research on the basic mechanisms of inner ear function, development, and therapeutic strategies. The Core Center user base comprises more than a dozen Principal Investigators working on a broad range of molecular, biophysical, developmental, whole animal, as well as engineering based projects all on topics that are of relevance to the mission of the NIDCD. Three goals are being pursued in both cores with an overarching strategy and philosophy where the Core Center serves as a hub for knowledge and technology (Aim 1) with the goal of generating an informed user base where students, postdoctoral fellows, and faculty share successes but most importantly also problems and solutions. This, in turn, stimulates collaborative research (Aim 2) because it teaches critical thinking and solving problems as a team. Finally, the Core Center makes available access to state-of-the-art technology (Aim 3) uniquely applicable to solving inner ear-related questions and research. These resources would be out of reach for a single laboratory simply because the costs to maintain and appropriately utilize the equipment would be economically unbearable.
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Regenerative pathways in the avian cochlea
  • 批准号:
    10439301
  • 项目类别:
  • 资助金额:
    $66.17万
  • 财政年份:
    2022
  • 负责人:
    Stefan Heller
  • 依托单位:
Otic Guidance
  • 批准号:
    10519111
  • 项目类别:
  • 资助金额:
    $15.74万
  • 财政年份:
    2021
  • 负责人:
    Stefan Heller
  • 依托单位:
High efficient AAV-transducible transgenic quails
  • 批准号:
    10285996
  • 项目类别:
  • 资助金额:
    $23.79万
  • 财政年份:
    2021
  • 负责人:
    Stefan Heller
  • 依托单位:
High efficient AAV-transducible transgenic quails
  • 批准号:
    10482370
  • 项目类别:
  • 资助金额:
    $19.86万
  • 财政年份:
    2021
  • 负责人:
    Stefan Heller
  • 依托单位:
国内基金
海外基金
分化肌细胞脱细胞ECM-cells sheet 3D 支架构建及其促进容积性肌组织缺损再 生修复应用及机制研究
CAFs-TAMs-tumor cells调控在HRHPV感染致癌中的作用机制研究及AI可追溯预测模型建立
  • 批准号:
    82072862
  • 项目类别:
    面上项目
  • 资助金额:
    56.0万元
  • 批准年份:
    2020
  • 负责人:
    徐云升
  • 依托单位:
S100A8/A9--Myeloid cells特异性可溶性表氧化物水解酶(sEH)基因敲除改善胰岛素抵抗的新靶点
  • 批准号:
    82070825
  • 项目类别:
    面上项目
  • 资助金额:
    53.0万元
  • 批准年份:
    2020
  • 负责人:
    徐西振
  • 依托单位:
Leader cells通过CCL5调控糖酵解及基质硬度促进结直肠癌集体侵袭的 作用机制
  • 批准号:
    81903002
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.5万元
  • 批准年份:
    2019
  • 负责人:
    王斐斐
  • 依托单位: