Enabling Data Science in Biology

实现生物学中的数据科学

• 批准号: 9036603
• 负责人: CATHERINE L LAWSON
• 金额: $ 5.56万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9036603
• 关键词: Archives; Area; Bioinformatics; Biological; Biological Models; Biology; Collaborations; Communities; Data; Databases; Deposition; Diagnostic; Disease; Education; Educational Curriculum; Educational Materials; Environment; Exercise; Faculty; Feedback; Health; Human; Information Specialists; Instruction; International; Knowledge; Librarians; Nucleic Acid Databases; Practice Management; Process; Proteins; Provider; Recommendation; Research; Research Infrastructure; Resources; Science; Scientist; Services; Slide; Structural Biologist; Testing; Training; Transcript; Work; base; collaboratory; data management; data modeling; experience; knowledge base; lectures; programs; public health relevance; simulation; structural biology; usability

 DESCRIPTION (provided by applicant): The aim of this proposal is to develop, pilot test, and deliver a new open access modular educational curriculum, Enabling Data Science in Biology (eDSB). eDSB will cover concepts, approaches and requirements for developing and managing the full data pipeline for a curated public archive of biological experimental data contributed by large community of data providers. The Program Director and Program Faculty responsible for developing and delivering the eDSB curriculum are experienced structural biologists, data scientists, and educators drawn from the senior ranks of the Research Collaboratory for Bioinformatics (RCSB). The RCSB develops and manages a number of data resources including the Protein Data Bank (PDB, with international partners), EMDataBank (with international partners), the Structural Biology Knowledgebase, and the Nucleic Acid Database, and develops educational materials and curricula to promote data resource usage. The RCSB built the infrastructure for these data resources and has successfully managed them over the past 20 years, during the course of a rapid expansion in the area of Structural Biology. eDSB will make best practices recommendations for data resource management based on the extensive experience accumulated by the RCSB team. The RCSB team is highly motivated to transfer its knowledge to new data resource builders and providers. The intended eDSB audience includes librarians and information specialists, who will be able to use the materials as a basis for training and services offered by their organizations, and scientists for self-instructin. In addition, the eDSB curriculum will allow the RCSB and its international partners to catalyze formation of a proposed federated system of model and data archives that will accelerate progress in the realm of Integrative Structural Biology. The eDSB curriculum will be divided into eight Modules that can either be studied separately or assembled into a complete set as an open online course.

 描述（由申请人提供）：本提案的目的是开发，试点测试和提供一个新的开放获取模块化教育课程，使生物学数据科学（eDSB）。eDSB将涵盖开发和管理完整数据管道的概念，方法和要求，用于大型数据提供商社区贡献的生物实验数据的策划公共档案。负责开发和提供eDSB课程的项目主任和项目教师是经验丰富的结构生物学家，数据科学家和教育工作者，他们来自生物信息学研究合作实验室（RCSB）的高级队伍。RCSB开发和管理许多数据资源，包括蛋白质数据库（PDB，与国际合作伙伴），EMDataBank（与国际合作伙伴），结构生物学知识库和核酸数据库，并开发教育材料和课程，以促进数据资源的使用。RCSB为这些数据资源建立了基础设施，并在过去20年中成功地管理了它们，在结构生物学领域迅速扩张的过程中。eDSB将根据RCSB团队积累的丰富经验，为数据资源管理提供最佳实践建议。RCSB团队非常积极地将其知识转移给新的数据资源构建者和提供者。eDSB的目标受众包括图书馆员和信息专家，他们将能够使用这些材料作为其组织提供的培训和服务的基础，以及进行自我指导的科学家。此外，eDSB课程将允许RCSB及其国际合作伙伴促进拟议的模型和数据档案联合系统的形成，这将加速综合结构生物学领域的进展。eDSB课程将分为八个模块，可以单独学习，也可以作为一个开放的在线课程组合成一套完整的课程。