NRSA Training Core

NRSA 培训核心

• 批准号: 9314020
• 负责人: TIMOTHY De Ver DYE
• 金额: $ 51.15万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9314020
• 关键词: Academic support; Address; Area; Award; Big Data; Bioinformatics; Biological Markers; Clinical; Clinical Research; Clinical Sciences; Communities; Creativeness; Data Analytics; Data Science; Development; Discipline; Doctor of Philosophy; Education; Electronic Health Record; Evaluation; Evidence based practice; Fellowship; Genotype; Goals; Health Care Reform; Healthcare; Infection; Institutes; Institution; Interdisciplinary Study; Learning; Link; Medical; Medical Education; Mentors; Methods; Minority-Serving Institution; Modeling; National Research Service Awards; Phenotype; Physicians; Population; Postdoctoral Fellow; Recording of previous events; Research; Research Personnel; Research Training; Role; Science; Scientist; Structure; Students; TNFSF15 gene; Training; Training Programs; Training Support; Translational Research; Universities; Vision; base; biopsychosocial; experience; flexibility; health care delivery; improved; innovation; multidisciplinary; novel; personalized medicine; population health; pre-doctoral; precision medicine; programs; tool; training opportunity

The University of Rochester (UR) has a decades-long distinguished history in innovative clinical research education, enhanced substantially since 2006 with the establishment and focus of the University of Rochester Clinical and Translational Science Institute (UR-CTSI). Building historically on the groundbreaking concept of medical education based on the biopsychosocial model starting in the 1940s with Engel and Romano, the UR has continued to create paradigm-shifting educational reform integrating research and systematic evaluation with problem-based medical education, community engagement and population health, and mentored field experience. This culture of creativity and innovation in pre-doctoral research training supported through prior TL1 awards is embodied by an institutional focus on research training from molecules to populations. Through this and other means, the UR-CTSI has created an institution-wide focal point for multidisciplinary research training. Further, UR-TL1-supported students in the 50+ year-old UR MD/PhD training program (Medical Scientist Training Program (MSTP)) have taken advantage of the UR-CTSI's PhD program in Translational Biomedical Science and other multidisciplinary graduate training options. In addition, the UR-TL1-supported Academic Research Track (ART) further provides a pipeline of clinical and translational research-prepared academic physicians through a comprehensive research training and mentoring experience. Predoctoral training is a priority within Rochester's CTSI, is well-integrated, and has successfully generated productive, employed clinical researchers, both within and outside of academics. The vision for the UR-TL1 in the next era of UR-CTSI is inspired by several critical developments in the healthcare and institutional landscape of Rochester and the US more broadly, namely: 1) Implementation of national health care reform prioritizing evidence-based practice and population health, 2) rapid emergence of data science and “Big Data” analytic opportunities and methodological approaches to healthcare and population health, and 3) emergence of precision medicine research and healthcare delivery using phenotype- genotype and biomarker-informed science. The goals for the coming five years include 1) to grow a pipeline of clinical and translational researchers able to address new and emerging scientific and methodological domains; 2) to enhance experiential and didactic learning through new training opportunities and partnerships that emphasize team science; 3) to stimulate creative and novel population health research that involves leveraging new tools and methods through establishing a University-wide Post-Doctoral Fellowship in Population Health; and 4) to rigorously evaluate the role of the UR-TL1 Training Program on the development of the clinical and translational research pipeline and disseminate learnings from the training program.

罗切斯特大学 (UR) 在创新临床研究方面拥有数十年的杰出历史 自 2006 年以来，随着罗切斯特大学的成立和重点关注，教育得到了大幅加强 临床和转化科学研究所 (UR-CTSI)。历史性地建立在开创性的概念之上 基于生物心理社会模型的医学教育始于 20 世纪 40 年代 Engel 和 Romano、UR 继续创造将研究和系统评估结合起来的范式转变的教育改革 以问题为基础的医学教育、社区参与和人口健康以及指导领域 经验。博士前研究培训中的创造力和创新文化得到了先前的支持 TL1 奖项体现了机构对从分子到群体的研究培训的关注。通过 通过这种方式和其他方式，UR-CTSI 为多学科研究创建了一个全机构范围的焦点 训练。此外，UR-TL1 支持学生参加 50 岁以上的 UR MD/PhD 培训项目（医学 科学家培训计划 (MSTP)）利用了 UR-CTSI 的转化博士计划 生物医学科学和其他多学科研究生培训选择。此外，UR-TL1支持 学术研究轨道（ART）进一步提供了临床和转化研究准备的管道 学术医师通过全面的研究培训和指导经验。博士前 培训是罗彻斯特 CTSI 的首要任务，它得到了很好的整合，并成功地产生了富有成效的、 雇用学术界内外的临床研究人员。 UR-CTSI 下一个时代的 UR-TL1 愿景受到以下几项关键发展的启发： 罗切斯特和美国更广泛的医疗保健和机构环境，即： 1) 实施 国家医疗保健改革优先考虑循证实践和人口健康，2) 快速出现 数据科学和“大数据”分析机会以及医疗保健和医疗保健的方法论方法 人口健康，以及 3) 使用表型的精准医学研究和医疗保健服务的出现- 基因型和生物标记信息科学。未来五年的目标包括 1) 扩大管道 临床和转化研究人员能够解决新兴的科学和方法论问题 域； 2）通过新的培训机会和伙伴关系加强体验式和教学式学习 强调团队科学； 3) 激发创造性和新颖性的人口健康研究，其中涉及 通过建立全校范围内的博士后奖学金来利用新的工具和方法 人口健康； 4) 严格评估 UR-TL1 培训计划对发展的作用 临床和转化研究渠道并传播培训计划的经验教训。