NRSA Training Core

罗切斯特大学(UR)在创新临床研究方面有着数十年的杰出历史 教育，自2006年以来随着罗切斯特大学的建立和重点大大加强 临床与翻译科学研究所(UR-CTSI)。历史性地建立在开创性的概念上 医学教育始于20世纪40年代恩格尔和罗马诺的生物-心理-社会模式 继续创造整合研究和系统评估的转变范式的教育改革 以问题为基础的医学教育、社区参与和人口健康，以及指导领域 经验。这种在博士前研究培训中的创造力和创新文化通过PIRE TL1奖项体现在机构对从分子到群体的研究培训的关注。穿过 通过这种方式和其他方式，UR-CTSI为多学科研究创建了一个机构范围的联络点 训练。此外，UR-TL1支持的学生参加了50年的UR MD/PhD培训计划(医学 科学家培训计划(MSTP))利用了UR-CTSI的翻译博士计划 生物医学和其他多学科研究生培训方案。此外，UR-TL1支持 学术研究轨道(ART)进一步提供了临床和转化性研究准备的渠道 学术内科医生通过全面的研究、培训和指导经验。博士前 培训是罗切斯特CTSI的优先事项，是很好地整合的，并成功地产生了生产力、 聘请了学术机构内外的临床研究人员。 UR-TL1在UR-CTSI的下一个时代的愿景是受到以下几个关键发展的启发 更广泛地说，罗切斯特和美国的医疗保健和机构格局，即：1)实施 以循证实践和人口健康为重点的国家医疗改革，2)迅速出现 数据科学和“大数据”分析机会和方法论方法 人口健康，以及3)使用表型的精准医学研究和医疗保健服务的出现- 基因分型和生物标记物信息科学。未来五年的目标包括1)发展一条 临床和翻译研究人员能够处理新的和新兴的科学和方法学 2)通过新的培训机会和伙伴关系加强体验式和指导性学习 强调团队科学；3)鼓励创造性和新颖的人口健康研究，包括 通过在全大学范围内建立博士后奖学金来利用新的工具和方法 人口健康；4)严格评估UR-TL1培训计划在发展中的作用 临床和转化性研究管道，并传播培训计划中的经验教训。

The University of Rochester (UR) has a decades-long distinguished history in innovative clinical research education, enhanced substantially since 2006 with the establishment and focus of the University of Rochester Clinical and Translational Science Institute (UR-CTSI). Building historically on the groundbreaking concept of medical education based on the biopsychosocial model starting in the 1940s with Engel and Romano, the UR has continued to create paradigm-shifting educational reform integrating research and systematic evaluation with problem-based medical education, community engagement and population health, and mentored field experience. This culture of creativity and innovation in pre-doctoral research training supported through prior TL1 awards is embodied by an institutional focus on research training from molecules to populations. Through this and other means, the UR-CTSI has created an institution-wide focal point for multidisciplinary research training. Further, UR-TL1-supported students in the 50+ year-old UR MD/PhD training program (Medical Scientist Training Program (MSTP)) have taken advantage of the UR-CTSI's PhD program in Translational Biomedical Science and other multidisciplinary graduate training options. In addition, the UR-TL1-supported Academic Research Track (ART) further provides a pipeline of clinical and translational research-prepared academic physicians through a comprehensive research training and mentoring experience. Predoctoral training is a priority within Rochester's CTSI, is well-integrated, and has successfully generated productive, employed clinical researchers, both within and outside of academics. The vision for the UR-TL1 in the next era of UR-CTSI is inspired by several critical developments in the healthcare and institutional landscape of Rochester and the US more broadly, namely: 1) Implementation of national health care reform prioritizing evidence-based practice and population health, 2) rapid emergence of data science and “Big Data” analytic opportunities and methodological approaches to healthcare and population health, and 3) emergence of precision medicine research and healthcare delivery using phenotype- genotype and biomarker-informed science. The goals for the coming five years include 1) to grow a pipeline of clinical and translational researchers able to address new and emerging scientific and methodological domains; 2) to enhance experiential and didactic learning through new training opportunities and partnerships that emphasize team science; 3) to stimulate creative and novel population health research that involves leveraging new tools and methods through establishing a University-wide Post-Doctoral Fellowship in Population Health; and 4) to rigorously evaluate the role of the UR-TL1 Training Program on the development of the clinical and translational research pipeline and disseminate learnings from the training program.