NorthStar Node of the Clinical Trials Network

 描述：物质使用障碍(SUD)是造成全球疾病负担的重要因素。仅在美国，酒精、烟草和其他毒品每年的直接和间接经济成本估计就高达5000亿美元。据估计，有2020万美国人需要治疗SUD，但只有不到5%的人接受了专门的治疗。在美国，最频繁的卫生保健接触点是门诊初级保健。明尼苏达州的健康状况在美国排名第一，是美国初级保健覆盖率最高的州之一。建议的NIDA临床试验网络的NorthStar节点将在初级保健的提供和研究方面出类拔萃的各种保健提供模式结合在一起。由在成瘾方面拥有实践和研究专长的内科医生领导的北极星节点包括：1)两个主要的非营利性综合健康系统，通过100多家初级保健诊所(HealthPartners和Allina Health)为100多万明尼苏达州人提供服务；2)联邦合格的健康中心(NorthPoint Health&Wellness Center)；3)一个负责管理明尼苏达州人口最多的县的最贫穷和医疗保健利用率最高的人口的责任护理组织(Hennepin Health)；4)一个学生健康中心，为20,000多名大学生提供初级和行为护理(明尼苏达大学的Boynton Health Services)；5)临床系统改进研究所(ICSI)，这是一个非营利性的健康改善组织，致力于在超过45个医疗系统和8,000名医生中开发和实施质量改进和最佳实践方案；以及6)明尼苏达大学临床和转换科学研究所。在完成CTN使命时，北极星节点将开发(1)SUD患者慢性护理疾病协调管理模型，(2)初级保健中用于慢性疼痛管理的阿片类药物处方的风险分层工具，(3)以阿片类药物使用障碍治疗为重点的临床决策支持工具，(4)戒烟治疗和艾滋病毒初级保健的综合模式，以及(5)降低SUD患者或普通医疗机构出院的高危用户30天再住院率的有效模式。

 DESCRIPTION: Substance use disorders (SUD) are significant contributors to the global burden of disease. Annual direct and indirect economic costs of alcohol, tobacco, and other drugs have been estimated at $500 billion in the United States alone. An estimated 20.2 million Americans are in need of treatment for a SUD, yet fewer than 5% receive specialty treatment. The most frequent point of health care contact in the United States is outpatient primary care. Minnesota ranks 1st in the US for health status and has one of the highest rates of access to primary care in the US. The proposed NorthStar node of the NIDA Clinical Trials Network brings together diverse healthcare delivery models that excel in delivery and research of primary care. Led by internal medicine physicians with practice and research expertise in addiction, the NorthStar node includes: 1) two major non-profit integrated health systems serving more than 1 million Minnesotans through over 100 primary care clinics (HealthPartners and Allina Health); 2) a Federally Qualified Health Center (NorthPoint Health & Wellness Center); 3) an accountable care organization managing the poorest and highest healthcare utilizing populations of Minnesota's most populous county (Hennepin Health); 4) a student health center, which provides primary and behavioral care for the more than 20,000 university students (University of Minnesota's Boynton Health Services); 5) the Institute for Clinical Systems Improvement (ICSI), a non-profit health improvement organization dedicated to developing and implementing quality improvement and best-practices protocols across more than 45 health systems and 8,000 physicians; and 6) the University of Minnesota Clinical and Translational Sciences Institute. In fulfillment of the CTN mission, the NorthStar node will develop (1) models of coordinated chronic care disease management of patients with SUD, (2) risk stratification tools for opiate prescription for chronic pain management in primary care, (3) clinical decision support tools focusing on the treatment of opiate use disorders, (4) integrated models of tobacco cessation treatment and HIV primary care, and (5) effective models to reduce 30-day readmission rates for SUD patients or at-risk users discharged from inpatient general medical settings.