Indiana University Melvin and Bren Simon Cancer Center Support Grant

描述（由申请人提供）：印第安纳大学梅尔文和布伦西蒙癌症中心是一个矩阵癌症中心，组织和促进癌症研究，教育，病人护理，癌症控制和预防。印第安纳大学梅尔文和布伦西蒙癌症中心的使命是通过开展杰出的转化研究，提供卓越的教育和提供高质量的以患者为中心的护理，降低癌症的死亡率和痛苦。该申请为该中心的五个研究项目，七个共享设施寻求资金。临床方案和数据管理，方案审查和监测系统，早期临床研究支持，数据安全与监测。此外，行政管理、计划与评估、发展基金及高级领导人也需要经费。研究项目的组织和发展是高度互动的，允许基础、临床和人口科学研究人员之间的成功合作。主要研究方向为：1)乳腺癌，2)癌症预防与控制，3)实验与发育治疗，4)造血、微环境与免疫学，5)肿瘤微环境与转移。支持这些项目成员的是七项共享资源。临床前共享资源：1)化学基因组学，2)流式细胞术，3)体内治疗学。临床共享资源：1)临床药理学与分析核心，2)组织采购与分配。其他共享资源：生物统计学和数据管理

DESCRIPTION (provided by applicant): The Indiana University Melvin and Bren Simon Cancer Center is a matrix Cancer Center that organizes and facilitates cancer research, education, patient care, and cancer control and prevention. The Mission of the Indiana University Melvin and Bren Simon Cancer Center is to decrease the mortality and suffering from cancer by conducting outstanding translational research, by providing excellence in education, and by delivering high quality patient-centered care. This application seeks funds for the Center's five research programs, seven shared facilities. Clinical Protocol and Data Management, Protocol Review and Monitoring System, Early Phase Clinical Research Support, and Data Safety and Monitoring. In addition, funds are requested for Administration, Planning and Evaluation, Developmental Funds, and Senior Leaders. The research programs have been organized and developed to be highly interactive, allowing for successful collaboration among basic, clinical, and population science researchers. The research programs are: 1) Breast Cancer, 2) Cancer Prevention and Control, 3) Experimental and Developmental Therapeutics, 4) Hematopoiesis, Microenvironment and Immunology, 5) Tumor Microenvironment and Metastasis. Supporting the members of these programs are seven shared resources. Preclinical share resources: 1) Chemical Genomics, 2) Flow Cytometry,3) In Vivo Therapeutics. Clinical shared resources: 1) Clinical Pharmacology and Analytical Core, 2) Tissue Procurement and Distribution. Other shared resource: Biostatistics and Data Management