Core 2: Biostatistics Shared Resource Core

核心2：生物统计学共享资源核心

• 批准号: 10693373
• 负责人: Yu Shyr
• 金额: $ 19.14万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-21 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693373
• 关键词: Address; Bioinformatics; Bioinformatics Shared Resource; Biometry; Biostatistics Shared Resource; Cancer Center; Clinical; Clinical Trials; Collaborations; Computer software; Data Analyses; Development; Educational workshop; Ensure; Experimental Designs; Funding; Human Resources; Individual; Information Storage; Laboratory Study; Maintenance; Malignant Neoplasms; Manuscripts; Methodology; Methods; Participant; Pilot Projects; Publications; Quality Control; Questionnaire Designs; Reporting; Research; Research Design; Research Personnel; Retrieval; Role; Sample Size; Services; Statistical Data Interpretation; Tennessee; The Vanderbilt-Ingram Cancer Center at the Vanderbilt University; Training; Universities; Work; Writing; cancer health disparity; data cleaning; data quality; data visualization; database design; design; experimental study; investigator training; medical schools; member; multidimensional data; posters; power analysis; relational database; symposium

PROJECT SUMMARY: BIOSTATISTICS AND BIOINFORMATICS SHARED RESOURCE CORE In this application, we propose to intensify the role of our existing Meharry Medical College/Vanderbilt-Ingram Cancer Center/Tennessee State University Cancer Partnership (MVTCP) Biostatistics and Bioinformatics Shared Resource Core (BBSRC). The BBSRC will support the proposed two full projects and one pilot project; detailed and specific biostatistical and bioinformatic analysis plans are provided for each specific aim/sub-aim within each project. Sample size for each primary experiment is computed to provide high power to detect clinically or biologically relevant effects. For projects with high-dimensional data analyses, the methods described in the Research Strategy will be applied to assess data quality and then perform statistical analysis only after preprocessing to address quality issues. BBSRC support is required for all MVTCP studies, with biostatisticians and bioinformaticians from this core assigned to each project. BBSRC personnel have worked and will continue to work closely with project leaders to ensure the Biostatistics and Bioinformatics Shared Resource Core provides state-of-the-art statistical/bioinformatic support to the MVTCP.

项目概述：生物统计学与生物信息学共享资源核心