Angiogenesis and Vascular Disease

摘要 要求为题为“血管生成和血管疾病”的Keystone专题讨论会提供支助， 由Dr. M。作者：Luisa Iruela-Arispe，Timothy T.赫拉和考特尼·格里芬会议将于 2017年5月8日至12日，新墨西哥州圣达菲。血管生成对组织的生长和修复都至关重要 以及几种病理学的进展。血管内皮细胞的分子生物学研究进展 增长促进了已成功应用于疾病的治疗方法的发展， 视网膜病变和癌症。尽管取得了这些进展，但仍有许多工作要从基本的 控制血管生长的分子机制。这次会议将汇集研究的领导者 从基础科学，转化科学，生物技术和制药领域，讨论进展， 临床和转化研究领域。会议的目标是突出新的发现， 技术进步和治疗可能性。已建立和即将到来的调查人员都将 有充足的机会与初级调查员和学员进行非正式交流， 学院和轻松的气氛。通过促进跨学科的互动，会议将加强 血管生物学研究和临床医学应用。跨学科互动的机会 将进一步加强对线粒体，代谢和心脏，这将 与本次会议分享主旨演讲和全体会议。 与NHLBI的相关性：会议的中心主题侧重于调节血管的机制 疾病期间的生长和失调。专注于解决血管健康问题的研究是 NHLBI的主要使命，因此，我们认为，该研究所不仅支持，而且拥抱 讨论了这一领域的最新进展。

ABSTRACT Support is requested for a Keystone Symposia conference entitled Angiogenesis and Vascular Disease, organized by Drs. M. Luisa Iruela-Arispe, Timothy T. Hla and Courtney Griffin. The conference will be held in Santa Fe, New Mexico from May 8-12, 2017. Angiogenesis is critical to both the growth and repair of tissues as well as for the progression of several pathologies. Progress in our molecular understanding of vascular growth has facilitated the development of therapies that have been successfully applied in diseases such as retinopathy and cancer. Notwithstanding these advancements, much remains to be harnessed from the basic molecular mechanisms that control vascular growth. This conference will bring together leaders of research from basic science, translational science, biotechnology and pharmaceutical areas, to discuss progress in clinical and translational research areas. The goal of the conference is to highlight new discoveries, technological advances and therapeutic possibilities. Both established and up-and-coming investigators will have ample opportunities to interact informally and share views with junior investigators and trainees in a collegial and relaxed atmosphere. By promoting cross-disciplinary interactions, the conference will enhance vascular biology research and applications to clinical medicine. Opportunities for interdisciplinary interactions will be further enhanced by the concurrent conference on Mitochondria, Metabolism and Heart, which will share a keynote address and plenary session with this conference. Relevance to NHLBI: The central theme of the conference focuses on mechanisms that regulate vascular growth and their deregulation during disease. Research that focuses in addressing vascular health is one of the main missions of NHLBI, therefore we consider that the institute would not only support but embrace discussions related to recent advancements in this area.