Vectors, Pathogens and Diseases: Current Trends and Emerging Challenges

摘要 请求支持题为《病原体和疾病：当前》的Keystone专题讨论会 趋势和新兴挑战，由Maureen Coetzee博士、Josiane Etang博士、Stephen Torr博士和 斯科特·L·奥尼尔。大会将于2017年9月10日至14日在南非德班举行。这个 消除或根除几种媒介传播的疾病是世界卫生议程上的优先事项 这些疾病包括疟疾、淋巴丝虫病、盘尾丝虫病和锥虫病。可持续向量 控制是目前唯一的群众性预防战略。然而，成功受到许多挑战的阻碍。 由病媒和病原体构成。这些挑战包括蚊子对杀虫剂的耐药性。 以及寄生虫的抗药性，近期几乎没有缓解这些问题的能力。杀虫剂 在病媒和寄生虫中，耐药性是两个平行的现象。虽然联合用药一直是 为克服寄生虫对单一疗法的抗药性而开发的杀虫剂，只有四类杀虫剂可用于 病媒控制。巴西和东南亚意外出现寨卡病毒等虫媒病毒黄色 南部非洲的热病、登革热和基孔肯雅热等构成了各自独特的挑战。的主要目标 这次会议将回顾有关病媒和病原体的最新科学知识，这些病原体与 新出现或再次出现的疾病，以突出世界各地面临的问题，以解决 控制或消除病媒传播疾病的创新方法，并提高对 媒介传播疾病的概况和相关的新科学知识，旨在改善人类健康 脆弱的人类群体。此外，在实现淘汰赛的过程中，“走完最后一英里”所面临的困难。 将讨论监督、能力和资金等方面的问题。这次会议还旨在打破 病媒传播疾病研究界太过普遍运作的“昆虫筒仓”，提供了一个论坛 供研究人员互动、建立网络和合作伙伴关系、交流思想和进行创造性思考 纪律。

ABSTRACT Support is requested for a Keystone Symposia conference entitled Vectors, Pathogens and Diseases: Current Trends and Emerging Challenges, organized by Drs. Maureen Coetzee, Josiane Etang, Stephen Torr, and Scott L. O'Neill. The conference will be held in Durban, South Africa from September 10-14, 2017. The elimination or eradication of several vector-borne diseases is high on the agenda of the World Health Organization, including malaria, lymphatic filariasis, onchocerciasis and trypanosomiasis. Sustainable vector control is currently the only mass prevention strategy. Success, however, is hampered by many challenges posed by both the vectors and the pathogens. These challenges include insecticide resistance in mosquitoes and drug resistance in parasites with little on the immediate horizon to alleviate these problems. Insecticide and drug resistance are two parallel phenomena in vectors and parasites. While combination drugs have been developed to overcome parasite resistance to monotherapies, only four classes of insecticides are available for vector control. The unexpected emergence of arboviruses such as Zika in Brazil and south-east Asia, yellow fever in southern Africa, Dengue and Chikungunya, etc. pose their own unique challenges. The key goals of this conference are to review the latest scientific knowledge on vectors and pathogens that are responsible for emerging or re-emerging diseases, to highlight the problems facing various parts of the world, to address innovative methods for the control or elimination of vector-borne diseases and to enhance awareness of the landscape of vector-borne diseases and related new scientific knowledge aiming at improving the health of vulnerable human populations. In addition, the difficulties in “going the final mile” to achieve elimination, in terms of surveillance, capacity and funding, will be addressed. The conference also aims to break down the “insect silos” in which the vector-borne disease research community too commonly operates, providing a forum for researchers to interact, create networks and partnerships, exchange ideas, and think creatively across disciplines.