Retail Meat Surveillance in the State of Kansas as a Part of the National Antimicrobial Resistance Monitoring System

堪萨斯州零售肉类监测作为国家抗菌素耐药性监测系统的一部分

• 批准号: 9336874
• 负责人: Brian V. Lubbers
• 金额: $ 12.5万
• 依托单位: KANSAS STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9336874
• 关键词: Retail; Meat; Surveillance; State; Kansas

Project Summary Retail Meat Surveillance in the State of Kansas as a Part of the National Antimicrobial Resistance Monitoring System As a key activity in combating antimicrobial resistance, the National Antimicrobial Resistance Monitoring System (NARMS) conducts surveillance of resistance in foodborne pathogens and other enteric bacteria of food animals at the time of animal processing, in meat and poultry in retail, and in human foodborne infections. The retail food surveillance is coordinated by the Food and Drug Administration (FDA) and in 2015 included 14 of the U.S. mainland states. The goal of this project is to extend the retail food surveillance activities to Kansas, one of the major food animal producing states of the nation. The enhanced retail food surveillance method used by the NARMS since 2015 will be implemented in Kansas. Eighty meat and poultry products from retail stores in the state will be sampled monthly. To accurately reflect exposure of the state's population to resistance in food, the sampling will be stratified to use randomly selected stores in most, moderately and least populated areas, with the sampling intensity in each area type proportional to percentage of the state's population residing there. Each of the meat and poultry samples will be analyzed for presence of Salmonella spp., Escherichia coli, and Enterococcus spp.; poultry samples also for Campylobacter spp. Epidemiological data about the production, origin, packaging, and retailing of the meat and poultry sampled will be collated and provided to the NARMS. The bacterial isolates will be subjected by the FDA to tests for antimicrobial resistance and other epidemiologically-relevant tests (e.g., Salmonella serotyping, Campylobacter speciation). The results will be used by the NARMS to enhance resistance surveillance and foodborne outbreak analysis at the national level. The results will also be returned to Kansas where they will be integrated with data on human foodborne infections, to support analysis of foodborne outbreaks by the state public health authorities, and guide public health action. The results will be delivered to clinicians to inform antimicrobial stewardship in treating foodborne infections. The results will further be innovatively used in the state to integrate data on resistance in the food animal populations, retail food, and humans. The integrated data will be analyzed to advance understanding of resistance dynamics between the animals, food, and humans. This project will strengthen surveillance and analysis of antimicrobial resistance, support foodborne outbreak analysis, and thus promote public health in Kansas and nation-wide.

项目概要 堪萨斯州的零售肉类监管作为国家监管的一部分 抗菌药物耐药性监测系统 作为对抗抗菌素耐药性的一项关键活动，国家抗菌素 耐药监测系统（NARMS）对以下地区的耐药情况进行监测 动物饲养时食用动物的食源性病原体和其他肠道细菌 加工、肉类和家禽零售以及人类食源性感染。零售业 食品监督由美国食品和药物管理局 (FDA) 负责协调 2015 年包括美国大陆 14 个州。该项目的目标是扩展 堪萨斯州（主要食用动物生产地之一）的零售食品监测活动 国家。 NARMS 使用的强化零售食品监测方法 自2015年起将在堪萨斯州实施。八十种零售肉类和家禽产品 该州的商店将每月进行一次抽样。准确反映国家暴露情况 人群对食物的抗药性，抽样将分层使用随机抽取 商店分布在大多数、中等和人口最少的地区，抽样强度为 每种区域类型与居住在那里的州人口百分比成正比。每个 将分析肉类和家禽样品中是否存在沙门氏菌， 大肠杆菌和肠球菌属；家禽样品也适用于弯曲杆菌属。 有关肉类生产、原产地、包装和零售的流行病学数据 家禽样本将进行整理并提供给 NARMS。细菌分离株 将接受 FDA 的抗菌素耐药性和其他测试 流行病学相关测试（例如沙门氏菌血清分型、弯曲杆菌 物种形成）。 NARMS 将使用结果来加强耐药性监测 以及国家层面的食源性疫情分析。结果也会返回 到堪萨斯州，在那里它们将与人类食源性感染的数据整合， 支持州公共卫生当局对食源性疫情的分析，并指导 公共卫生行动。结果将提供给临床医生以告知抗菌药物 治疗食源性感染的管理。成果将进一步创新利用 在该州整合食用动物种群、零售食品、 和人类。将分析综合数据以加深对 动物、食物和人类之间的阻力动态。该项目将 加强抗菌药物耐药性监测分析，支持食源性食品传播 疫情分析，从而促进堪萨斯州和全国范围内的公共卫生。