2017 Malaria Gordon Research Conference & Gordon Research Seminar

项目摘要/摘要 2017疟疾戈登研究会议暨戈登研究研讨会 蚊子传播的疟疾寄生虫导致了大约2亿例 疟疾和全世界每年40万人死亡，其中绝大多数是由疟疾引起的 恶性疟原虫。令人鼓舞的是，加强蚊子控制措施和增加分发防蚊药物 疟疾药物，如以青蒿素为基础的联合疗法，与减轻负担有关 疟疾在世界许多地区的流行。然而，这些抗击疟疾的微不足道的成果一直在 受抗药性蚊子的出现和青蒿素抗药性的传播的威胁。 恶性寄生虫。因此，人们普遍认为，加快疟疾控制和实现 根除疟疾的最终目标将需要新的工具，包括一种高效的疟疾疫苗、新的 抗疟疾药物和改进的蚊媒控制战略。为了成功应对这些挑战，a 更清楚地了解疟原虫、其蚊媒和疟疾之间的复杂相互作用 它感染的脊椎动物宿主是必要的。2017年戈登疟疾研究会议(GRC)将重点关注 疟原虫生命周期各阶段感染的基础生物学研究进展。要设置 为一次发人深省的会议做准备，该项目由疟疾和非疟疾科学家组成，网址为 走在他们领域的前沿。该计划的目的是通过以下方式刺激创新想法和合作 提供一个论坛，讨论前沿的疟疾基础研究以及非疟疾领域的最新进展 可能与疟疾相关的油田。在会议之前，疟疾戈登研究中心将 2017年7月1日至2日举行的研讨会(GRS)，面向研究生、博士后和初级科学家。

Project Summary/Abstract 2017 Malaria Gordon Research Conference & Gordon Research Seminar The mosquito-transmitted Plasmodium parasites are responsible for approximately 200 million cases of malaria and 400,000 deaths annually worldwide, the vast majority of which are caused by Plasmodium falciparum. Encouragingly, the scale up of mosquito control measures and increased distribution of anti- malarial drugs, such as artemisinin-based combination therapy, have been associated with a reduced burden of malaria in many regions of the world. However, these tenuous gains against malaria are constantly threatened by the emergence of insecticide-resistant mosquitoes and the spread of artemisinin-resistant P. falciparum parasites. Consequently, there is broad consensus that accelerating malaria control and achieving the ultimate goal of malaria eradication will require new tools, including a highly effective malaria vaccine, new anti-malarial drugs and improved mosquito vector control strategies. To successfully meet these challenges, a clearer understanding of the complex interplay between the Plasmodium parasite, its mosquito vector and the vertebrate host it infects is needed. The 2017 Gordon Research Conference (GRC) on Malaria will focus on advances in the basic biology of Plasmodium infection at each stage of the parasite's life cycle. To set the stage for a thought-provoking meeting, the program is composed of both malaria and non-malaria scientists at the forefront of their fields. The aim of this program is to stimulate innovative ideas and collaborations by providing a forum to discuss cutting edge basic malaria research as well as recent advances in non-malaria fields with potential relevance to malaria. The conference will be preceded by the Malaria Gordon Research Seminar (GRS) from July 1-2, 2017 targeted at graduate students, post-docs and junior scientists.