One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia

蒙古人畜共患疾病研究健康创新奖学金

• 批准号: 9114184
• 负责人: Gregory Charles Gray
• 金额: $ 31.5万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-27 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9114184
• 关键词: Address; Advisory Committees; American; Animal Experimentation; Animals; Anthrax disease; Brucellosis; Budgets; Cattle; Collaborations; Complex; Country; Diagnostic; Diagnostics Research; Disease; Economics; Environmental Engineering technology; Environmental Health; Epidemic; Ethics; Fellowship; Florida; Food Safety; Fostering; Funding; Goals; Goat; Government; Health; Health Professional; Health education; Hour; Human; Income; Influenza; Institution; Intervention; Marketing; Mentors; Mining; Modeling; Mongolia; Morbidity - disease rate; Persons; Phase; Pilot Projects; Policies; Population; Postdoctoral Fellow; Prevention; Problem Solving; Process; Production; Public Health; Rabies; Research; Research Project Grants; Research Training; Resources; Rickettsia; Risk; Science; Sheep; Techniques; Technology; Trainers Training; Training; Training Programs; Translating; Travel; Universities; burden of illness; disorder control; disorder prevention; environmental change; experience; global health; health economics; health training; improved; infrastructure development; innovation; institutional capacity; laboratory facility; low and middle-income countries; meetings; member; multidisciplinary; novel; operation; post-doctoral training; programs; surveillance network; urban area

DESCRIPTION (provided by applicant): Responding to the Framework Programs for Global Health Innovation, this proposal builds upon an established US-Mongolia multidisciplinary partnership to address zoonotic disease burdens in Mongolia. In recent decades, Mongolia has experienced major economic and environmental changes, and suffered many large epidemics of zoonotic diseases. The long term goal of this submission is to develop a global health training program that elicits innovative, multidisciplinary team problem-solving solutions to develop products, alter disease processes, and guide policies in controlling zoonotic diseases in low- or middle- income countries. In this effort, we will employ One Health cross-disciplinary training and foster collaborations in public, veterinary, and environmental health sectors for one American and two Mongolian postdoctoral trainees per year (2-yr training period). These professionals will comprise a 3-person 'One Health' team that represents each of the three health sectors. Over the 5-yr period 4 such teams (12 postdoctoral fellows) will be engaged in zoonotic disease problem solving. In Phase I of the 2-yr period, teams will convene at the University of Florida (UF) for 2 months of training. They will receive 9 credit hours of One Health didactic training (Certificate in One Health) as well as training in ethical conduct of human and animal research. While in Florida, the postdoctoral teams will meet each week with a six- member Internal Advisory Committee (IAC, 4 US and 3 Mongolian members) who will pose zoonotic disease problems and guide them in engaging diverse expert groups at UF in developing a pilot research project and budget. While in Florida, the postdoctoral team will pitch their zoonotic disease problems and their ideas for projects to various professional groups at UF (e.g. animal science, food safety, environmental engineers, ecologists, geographers, as well as emerging disease, public health, and veterinary health professionals) with a goal of identifying innovative solutions to the problem and identifying UF and later Mongolian research mentors. During the last week of Phase I training, the postdoctoral team will present their project to the IAC for final approval and research fund release. The postdoctoral team will then travel to Mongolia and set up a research headquarters in the most appropriate Mongolian government collaborating institution, and move forward with pilot study execution. While the postdoctoral team will have at least weekly contact with their mentors and monthly contact with the IAC, this program will emphasize independent team problem solving by the postdoctoral fellows. Mongolia will greatly benefit from the implementation of a One Health research framework for global health innovation. Since moving to a market economy in 1992, Mongolia has undergone rapid change with increases in mining operations and animal production of sheep, goats, and cattle. Large segments of the normally nomadic pastoral populations have begun migrating to urban areas and introducing previously unconnected human and animal populations to new environmental terrains. For complex reasons, both humans and animals have suffered from increased zoonotic diseases, including brucellosis, anthrax, zoonotic influenza, rabies, and rickettsia diseases. Zoonotic diseases are both economic and health threats, as a large portion of the country's economy continue to rely upon animal production. Yet due to limited resources, Mongolia's health professionals have limited research and diagnostic capacity. There is a tremendous need for infrastructure development in the public, veterinary, and environmental health sectors, improved diagnostic laboratory facilities, stronger surveillance networks, and advanced One Health education to address complex zoonotic disease prevention and control strategies. This program will strengthen institutional capacity for innovative zoonotic disease training and research at both the University of Florida and at the multiple collaborating health institutions in Mongolia. It will also serve as a model program for similar interventions in other LMIC countries with zoonotic disease burdens. The specific aims of this project are to 1) identify the risks and conditions associated with zoonotic disease morbidity in Mongolia; 2) by employing modern technologies available at a large multidisciplinary US university and following a cross-disciplinary team approach, develop innovative One Health strategies to solve zoonotic disease problems in Mongolia; 3) following a train-the-trainer approach, transfer novel prevention and control techniques to regional public, animal, and environmental health professionals throughout Mongolia; and 4) translate scientific findings into prevention practices or products that will help to reduce the burden of zoonotic diseases among pastoral people worldwide.

描述（由申请人提供）：响应全球卫生创新框架项目，该提案建立在已建立的美国-蒙古多学科伙伴关系的基础上，以解决蒙古人畜共患病负担。近几十年来，蒙古经历了重大的经济和环境变化，并遭受了多次人畜共患疾病的大规模流行。本次提交的长期目标是制定一项全球卫生培训计划，为中低收入国家开发产品、改变疾病进程和指导控制人畜共患疾病的政策提供创新的、多学科团队解决问题的解决方案。在这项工作中，我们将每年为一名美国和两名蒙古博士后培训生（2年培训期）提供“壹健康”跨学科培训，并促进公共、兽医和环境卫生部门的合作。这些专业人员将组成一个3人的“一个健康”小组，代表三个卫生部门中的每一个部门。在5年的时间里，将有4个这样的团队（12名博士后）从事人畜共患病问题的解决。在为期两年的第一阶段，团队将在佛罗里达大学（UF）进行为期两个月的培训。他们将获得9学时的One Health课程