Zoonotic Swine Influenza Virus Transmission in Confined Animal Feeding Operations
人畜共患猪流感病毒在封闭式动物饲养作业中的传播
基本信息
- 批准号:9110835
- 负责人:
- 金额:$ 42.71万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-08-15 至 2019-07-31
- 项目状态:已结题
- 来源:
- 关键词:AdultAerosolsAgeAnimal FeedAnimalsAntibodiesAreaAvian InfluenzaBiological AssayBiological MarkersBirthCambodiaChinaChinese PeopleCitiesCollaborationsCommunicable DiseasesCrowdingDiseaseDomestic FowlsEcologyEconomicsEnvironmentEpidemiologic StudiesEpidemiologyFamily suidaeFarming environmentFutureGeneral PopulationGenerationsGeneticGeographic Information SystemsGoalsHealthHigh PrevalenceHome environmentHousingHumanImmuneImmune responseIncubatorsIndustryInfectionInfluenzaInfluenza A Virus, H1N1 SubtypeInfluenza A virusInterventionLeadLifeMapsMucosal ImmunityNigeriaNorth AmericaOccupationalPeruPhylogenetic AnalysisPolymerase Chain ReactionPopulationPorcine Influenza A VirusPrevalenceProductionProspective StudiesPublic HealthReportingResearchResearch PersonnelReverse TranscriptionRiskRisk FactorsRomaniaSamplingSerologicalSiteSourceSwabThailandTimeUnited StatesVirusVirus DiseasesWeaningWorkage groupdensityenzooticexperienceinfluenza virus straininfluenza virus vaccineinfluenzavirusneutralizing antibodynovelnovel virusoperationpandemic diseasepandemic influenzaprospectiveswine influenzatransmission processviral transmissionwater sampling
项目摘要
DESCRIPTION (provided by applicant): With its dense interacting populations of people, pigs, and poultry, China has been implicated as the source of the 1957 and 1968 pandemic influenza viruses and considered an epicenter for generating novel influenza virus strains. As industrialized farming has increased in China, the prevalence and variety of swine influenza viruses (SIVs) have increased. In this controlled, 5-yr project, we will collaborate with leading Chinese infectious disease researchers and employ a One Health approach (human, animal, and environment) to study SIV transmission in Confined Animal Feeding Operations (CAFOs) in mainland China. We will select CAFOs with a high prevalence of SIVs and prospectively follow the swine workers and their pigs, as well as examine the CAFO environment as a source for SIV persistence and transmission. In this collaboration, our aims are: 1) to identify and characterize enzootic and emergent SIVs, 2) to employ aerosol, fecal, environmental swabs, and water sampling to identify environmental areas with a high prevalence of SIVs, 3) to identify occupational risk factors for SIV infection, and 4) to identify serological and mucosal immunity biomarkers of protection against prevalent and emergent SIVs. This One Health approach to zoonotic influenza virus research is unique and made possible by our Chinese collaborators who have unique access to their swine production industry.
描述(由申请方提供):由于其密集的人、猪和家禽相互作用的种群,中国被认为是1957年和1968年大流行性流感病毒的来源,并被认为是产生新型流感病毒株的中心。随着中国工业化养殖的增加,猪流感病毒(SIV)的流行和种类也有所增加。在这个为期5年的受控项目中,我们将与中国领先的传染病研究人员合作,采用一种健康方法(人,动物和环境)来研究中国大陆限制动物饲养操作(CAFO)中的SIV传播。我们将选择SIV高流行率的CAFO,并前瞻性地跟踪养猪工人和他们的猪,以及检查CAFO环境作为SIV持续存在和传播的来源。在这项合作中,我们的目标是:1)识别和表征地方性和突发性SIV,2)采用气溶胶,粪便,环境拭子和水采样来识别SIV高发的环境区域,3)识别SIV感染的职业危险因素,和4)识别针对流行和突发性SIV的血清学和粘膜免疫生物标志物。这种“同一健康”的人畜共患流感病毒研究方法是独一无二的,我们的中国合作者对他们的养猪业有独特的了解。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Gregory Charles Gray其他文献
“One Health”——解决食品安全问题的有效途径
- DOI:
- 发表时间:
2015 - 期刊:
- 影响因子:0
- 作者:
王安娜;黄琼;张永慧;Gregory Charles Gray;陆家海 - 通讯作者:
陆家海
Integrating One Health research in Sarawak, Malaysia: Addressing emerging and emre/em-emerging infectious disease through international collaboration
在马来西亚砂拉越整合“同一健康”研究:通过国际合作应对新出现及正在出现/即将出现的传染病
- DOI:
10.1016/j.onehlt.2025.101027 - 发表时间:
2025-06-01 - 期刊:
- 影响因子:4.500
- 作者:
Teck-Hock Toh;Jeffrey Soon-Yit Lee;Kamilah Dahian;Aw-Zien Toh;Jo-Hun Teh;Mohd Raili Suhaili;Gregory Charles Gray - 通讯作者:
Gregory Charles Gray
Gregory Charles Gray的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Gregory Charles Gray', 18)}}的其他基金
Zoonotic Swine Influenza Virus Transmission in Confined Animal Feeding Operations
人畜共患猪流感病毒在封闭式动物饲养作业中的传播
- 批准号:
8761305 - 财政年份:2014
- 资助金额:
$ 42.71万 - 项目类别:
Zoonotic Swine Influenza Virus Transmission in Confined Animal Feeding Operations
人畜共患猪流感病毒在封闭式动物饲养作业中的传播
- 批准号:
9323281 - 财政年份:2014
- 资助金额:
$ 42.71万 - 项目类别:
One Health Center for Environmental and Occupational Research-Romania/USA
罗马尼亚/美国环境和职业研究健康中心
- 批准号:
8865811 - 财政年份:2014
- 资助金额:
$ 42.71万 - 项目类别:
One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia
蒙古人畜共患疾病研究健康创新奖学金
- 批准号:
9114184 - 财政年份:2013
- 资助金额:
$ 42.71万 - 项目类别:
One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia
蒙古人畜共患疾病研究健康创新奖学金
- 批准号:
8598747 - 财政年份:2013
- 资助金额:
$ 42.71万 - 项目类别:
One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia
蒙古人畜共患疾病研究健康创新奖学金
- 批准号:
9320856 - 财政年份:2013
- 资助金额:
$ 42.71万 - 项目类别:
One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia
蒙古人畜共患疾病研究健康创新奖学金
- 批准号:
8743364 - 财政年份:2013
- 资助金额:
$ 42.71万 - 项目类别:
One Health Center for Environmental and Occupational Research - United States
环境与职业研究健康中心 - 美国
- 批准号:
9028016 - 财政年份:2012
- 资助金额:
$ 42.71万 - 项目类别:
One Health Center for Environmental and Occupational Research - United States
环境与职业研究健康中心 - 美国
- 批准号:
8441734 - 财政年份:2012
- 资助金额:
$ 42.71万 - 项目类别:
One Health Center for Environmental and Occupational Research - United States
环境与职业研究健康中心 - 美国
- 批准号:
8549865 - 财政年份:2012
- 资助金额:
$ 42.71万 - 项目类别:
相似海外基金
AEROSOLS - AIR QUALITY AND HEALTH IMPACT OF PRIMARY SEMI-VOLATILE AND SECONDARY PARTICLES AND THEIR ABATEMENT
气溶胶 - 一次半挥发性颗粒和二次颗粒对空气质量和健康的影响及其消除
- 批准号:
10092043 - 财政年份:2024
- 资助金额:
$ 42.71万 - 项目类别:
EU-Funded
Molecular-level Understanding Of Atmospheric Aerosols (MUOAA 2024); Corsica, France; April 1-5, 2024
对大气气溶胶的分子水平理解(MUOAA 2024);
- 批准号:
2332007 - 财政年份:2024
- 资助金额:
$ 42.71万 - 项目类别:
Standard Grant
TWISTA (The Wide-ranging Impacts of STratospheric smoke Aerosols)
TWISTA(平流层烟雾气溶胶的广泛影响)
- 批准号:
NE/Y000021/1 - 财政年份:2024
- 资助金额:
$ 42.71万 - 项目类别:
Research Grant
TWISTA (The Wide-ranging Impacts of STratospheric smoke Aerosols)
TWISTA(平流层烟雾气溶胶的广泛影响)
- 批准号:
NE/Y000358/1 - 财政年份:2024
- 资助金额:
$ 42.71万 - 项目类别:
Research Grant
Southern Ocean aerosols: sources, sinks and impact on cloud properties
南大洋气溶胶:来源、汇以及对云特性的影响
- 批准号:
DP240100389 - 财政年份:2024
- 资助金额:
$ 42.71万 - 项目类别:
Discovery Projects
INvestigating Home water and Aerosols' Links to opportunistic pathogen Exposure (INHALE): do consumer decisions impact pathogen exposure and virulence?
调查家庭用水和气溶胶与机会性病原体暴露(吸入)的联系:消费者的决定是否会影响病原体暴露和毒力?
- 批准号:
2326096 - 财政年份:2023
- 资助金额:
$ 42.71万 - 项目类别:
Standard Grant
An AI-driven clinical washbasin unit that automatically disinfects pathogens, reduces aerosols and decreases healthcare-acquired infections by 70%
%20人工智能驱动%20临床%20洗脸盆%20单位%20%20自动%20消毒%20病原体,%20减少%20气溶胶%20和%20减少%20医疗保健获得性%20感染%20by%2070%
- 批准号:
83001507 - 财政年份:2023
- 资助金额:
$ 42.71万 - 项目类别:
Innovation Loans
Cloudbusting with JWST: characterising aerosols, aurorae and chemistry in substellar atmospheresto the water cloud regime
使用 JWST 进行云消除:描述水云状态下恒星大气中的气溶胶、极光和化学成分
- 批准号:
ST/X001091/1 - 财政年份:2023
- 资助金额:
$ 42.71万 - 项目类别:
Research Grant
Bioactivated Aerosols for Combustion Product Capture
用于燃烧产物捕获的生物活性气溶胶
- 批准号:
10080253 - 财政年份:2023
- 资助金额:
$ 42.71万 - 项目类别:
Small Business Research Initiative