Chemistry-Biology Interface Training Grant

描述（由申请人提供）：这个令人兴奋的博士前培训项目在化学-生物学界面进行，涉及来自明尼苏达大学化学，药物化学，生物化学，分子生物学和生物物理学（BMBB）三个部门的31名培训教师。明尼苏达大学化学与生物工程学院的使命是为多样化的学生提供必要的技能，以跨越传统界限，理解和开展化学和生物界面的科学研究。这一任务将通过实现以下目标来完成：(i)通过结合至少两个系的课程，以及由一名联合导师参与的交叉培训经验，以及在联合导师的实验室中进行三个月的研究经验，为学生提供化学和生物学界面的跨学科培训经验。（ii）通过以这类界面科学为重点的研讨会（化学生物学讨论会），让学生接触化学和生物学界面的前沿科学，并允许他们组织自己的以化学生物学界面为重点的研讨会。提高受训者的沟通技巧，为他们提供多种机会介绍他们的研究，包括在国家或国际会议上进行介绍。教育学生了解在这方面受过训练的科学家可获得的各种职业机会。(v)通过与在化学/生物学领域工作的受训人员、培训人员和杰出科学家进行面谈，激发他们对我们培训计划的兴趣。增加在联合国进行研究的科学家的多样性

DESCRIPTION (provided by applicant): This exciting pre-doctoral training program at the Chemistry-Biology Interface involves 31 training faculty from three departments at the University of Minnesota: Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). The mission of the CBITG at the University of Minnesota is to provide a diverse cadre of students with the skills necessary to cross traditional boundaries and understand and conduct scientific research at the interface of chemistry and biology. This mission will be accomplished by achieving the following objectives: (i) Provide students with an interdisciplinary training experience at the interface of chemistry and biology through a combination of coursework involving classes from at least two departments and by a cross-training experience involving a coadvisor and a research experience of three months in the coadvisor's laboratory. (ii) Expose students to cutting-edge science at the interface of chemistry and biology through seminars focused on this type of interfacial science (Chemical Biology Colloquium) and by allowing them to organize their own symposium focused on the chemical biology interface. (iii) Enhance the communication skills of trainees by providing them with multiple opportunities to present their research including a presentation at a national or international conference. (iv) Educate students about the range of career opportunities available for scientists with training in this area. (v) Stimulate interest in our training program through te use of interviews with trainees, trainers and prominent scientists working at the chemistry/biology interface. (vi) Increase the diversity of scientists carrying out research at the chemistry and biology interface in our program through a combination of different outreach activities. Trainees will be involved in research themes that include: Biocatalysis and Biomolecular Design (Distefano, Kazlauskas, Lipscomb, Ohlendorf, Schmidt-Dannert, Seelig Wackett, Wagner, Wilmot), Therapeutic Agents (Aldrich, Amin, Bernlohr, Distefano, Georg, Harki, Haskell-Luevano, Hoye, Mansky, Tretyakova, Wagner, Xing), Chemistry of Disease (Aldrich, Arriaga, Bernlohr, Distefano, Harki, Haskell-Luevano, Mansky, Murphy, Pomerantz, Tretyakova, Wagner, Xing), Metallobiochemistry (Amin, Lipscomb, Murphy, Ohlendorf, Pierre, Que, Wackett, Wilmot), and Bioanalytical/Biophysical (Arriaga, Bowser, Griffin, Haynes, Pierre, Pomerantz, Tretyakova, Thomas, Veglia). The research groups of the training faculty are all well supported and well equipped. This highly successful training program has been ongoing for 14 years. In this period, support is requested for 8 trainees each year of the program, each to be supported for a two-year period.