Cancer Immunology Training Grant

癌症免疫学培训补助金

• 批准号: 9404561
• 负责人: Kai W Wucherpfennig
• 金额: $ 1.02万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-13 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9404561
• 关键词: Cancer Immunology Science; Grant; Training

Project Summary This training program is designed to train the next generation of scientists in Cancer Immunology at the Dana- Farber/Harvard Cancer Center, a Harvard-wide, NCI-designated Comprehensive Cancer Center. Recent clinical trials have demonstrated that cancer immunotherapy can induce durable responses in patients with diverse types of advanced cancer. The discovery that targeting of a single inhibitory receptor on immune cells can unleash durable anti-tumor immunity has far-reaching implications for oncology and raises many fascinating questions about the biological mechanisms that regulate anti-tumor immunity. The resulting rapid growth in the field of cancer immunology has created a significant need for scientists with in depth expertise at the interface of immunology and tumor biology. To address this need, we have built a comprehensive program supported by faculty who bring a wide spectrum of expertise in basic and translational cancer immunology. The preceptors of this grant have made a series of important contributions to cancer immunology and immunotherapy. We propose to appoint 2 predoctoral and 6 postdoctoral scientists per year. Our predoctoral trainees will be selected from a pool of students who have enrolled in the Immunology and Basic Biomedical Sciences Graduate Programs at Harvard Medical School. These students will be appointed after their second year of study once they have chosen one of our mentors as their thesis advisor and committed to a research topic in cancer immunology. The postdoctoral positions will be awarded to a select group of recent recipients of PhD and MD/PhD degrees and support their training in cancer immunology. Laboratory training in cancer immunology will be complemented by a didactic program that gives students the required background in cancer immunology and prepares them for independent careers in academic research, biotechnology or a broad range of other job opportunities. The program directors are highly committed to teaching and mentoring and have the required expertise to lead this effort. The Postdoctoral and Graduate Student Affairs Offices at Dana-Farber and Harvard Medical School provide a wide range of programs to all of our trainees designed to enhance their training experience and address individual needs. Retreats organized by the Harvard Immunology Program and the Department of Cancer Immunology and Virology at Dana-Farber will help to create a sense of community and give our trainees the opportunity to learn from other trainees and faculty.

项目摘要 该培训计划旨在培养下一代癌症免疫学科学家， 法伯/哈佛癌症中心，一个哈佛范围内的，NCI指定的综合癌症中心。最近 临床试验已经证明，癌症免疫疗法可以在患有癌症的患者中诱导持久的应答。 不同类型的晚期癌症。发现免疫细胞上的单一抑制性受体的靶向 可以释放持久的抗肿瘤免疫力，对肿瘤学具有深远的影响，并提出了许多 关于调节抗肿瘤免疫的生物学机制的有趣问题。由此产生的快速 癌症免疫学领域的发展对具有深入专业知识的科学家产生了重大需求， 免疫学和肿瘤生物学的界面。为了满足这一需求，我们建立了一个全面的计划， 由教师谁带来了基础和转化癌症免疫学的广泛专业知识的支持。的 该基金的导师们对癌症免疫学做出了一系列重要贡献， 免疫疗法我们建议每年任命2名博士前和6名博士后科学家。我们的博士预科生 受训人员将从参加免疫学和基础生物医学的学生中挑选。 哈佛医学院科学研究生课程。这些学生将在他们的第二次 一年的学习，一旦他们选择了我们的导师之一作为他们的论文导师，并致力于研究 癌症免疫学的主题。博士后职位将授予一组精选的最近获奖者， 博士和医学博士/博士学位，并支持他们在癌症免疫学的培训。癌症实验室培训 免疫学将由一个教学计划，为学生提供所需的背景， 癌症免疫学，并准备他们在学术研究，生物技术或 广泛的其他工作机会。项目主任高度致力于教学和指导 并拥有领导这项工作所需的专业知识。博士后及研究生事务处 丹娜法伯和哈佛医学院提供了广泛的计划，以我们所有的学员，旨在 提高他们的培训经验，满足个人需求。哈佛大学组织的静修会 丹娜-法伯大学的免疫学项目和癌症免疫学和病毒学系将帮助 创造一种社区意识，让我们的学员有机会向其他学员和教师学习。