Enhancing Recruitment and Retention of Underrepresented Pregnant Hispanic Women in a Phase III Randomized Clinical Trial

目前的提案没有改变我们正在进行的RCT（R 01）的原始范围、目标或研究设计 HD 083292; ClinicalTrials.gov ID：NCT 02626299），其试图确定高DHA与低DHA相比 在怀孕期间摄入可以成功地减少早期早产。相反，该提案要求增加 资源，以评估基于社区的参与性研究战略的招聘和保留 少数族裔，尤其是西班牙裔孕妇。我们寻求1）识别怀孕的障碍 西班牙裔妇女在获得临床护理时面临的问题，2）确定他们对临床研究参与的看法 因为这关系到她们怀孕和未出生的孩子的健康，3）增加入学率和保留率， 西班牙裔妇女在我们的临床试验，以实现全国代表性的抽样。一个新成立 跨学科合作与多语言，文化上适当的中心，成功的跟踪记录， 西班牙裔社区的参与将指导我们的努力。结果数据将包括西班牙裔人数 参加并完成我们的临床试验的参与者以及描述性方法， 代表性不足的少数群体对未来研究的承诺。

The current proposal does not change the original scope, aims or research design of our ongoing RCT (R01 HD083292; ClinicalTrials.gov ID: NCT02626299) which seeks to determine whether high versus low DHA intake during pregnancy can successfully reduce early preterm birth. Instead this proposal directs additional resources to evaluate community based participatory research strategies for the recruitment and retention of underrepresented minorities, specifically pregnant Hispanic women. We seek to 1) identify barriers pregnant Hispanic women face when accessing clinical care, 2) identify their perception of clinical research participation as it relates to the health of their pregnancy and unborn child and 3) increase enrollment and retention of Hispanic women in our clinical trial to achieve a nationally representative sampling. A newly formed interdisciplinary collaboration with a multilingual, culturally appropriate center with a successful track record of Hispanic community engagement will guide our efforts. Outcome data will include the number of Hispanic participants who enroll into and complete our clinical trial as well as descriptive methods to improve commitment of underrepresented minorities for future studies.