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中文摘要
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描述(由申请人提供):哈佛肾脏医学夏季研究计划旨在向有才华的本科生介绍丰富而令人兴奋的肾脏研究世界。该项目的核心特点是在哈佛医学院教职人员经验丰富且忠诚的研究人员的指导下进行深入的研究经验。研究活动可以是实验室科学或临床研究。项目将在哈佛大学附属的四个主要研究机构之一进行:布莱根妇女医院、贝斯以色列女执事医疗中心、马萨诸塞州总医院和波士顿儿童医院。每个站点的参与将由“站点矿工”(该机构的主要研究人员)提供便利,他们将帮助学生找到研究机会。肾脏病科负责人将确保机构承诺和支持。每个站点都承诺每年暑期至少招收 4 名学生。 学生还将参加核心课程,该课程包括两个核心组成部分:1)介绍肾脏生理学原理和疾病的基本机制以及疾病如何影响真实患者; 2) 评估个人慢性肾脏病的培训,并有机会参与由我们的肾脏病筛查和意识计划赞助的社区筛查工作。核心课程的另一个目标是提高学生从事科学事业的兴趣和信心。学生将接受实验设计和实施的基本方面的培训。社交活动将补充该计划的正式方面,以增强学生对研究社区的理解和发现的乐趣。每个机构的个别导师将帮助学生准备在当地展示他们的研究成果。学生还将参加 NIDDK 在马里兰州贝塞斯达筹划的标志性科学研讨会,以丰富这一密集体验。 该项目领导层将由一名主任和两名副主任组成,他们每个人都在指导许多处于不同发展阶段的学员(包括大学本科生)的职业生涯方面拥有丰富的经验。内部和外部监督委员会的成立是为了优化该计划的有效性,优化学生与研究导师的匹配,并为学生的职业选择提供建议和指导。此外,还设计了一个评估部分,以确定该计划对参与者职业生涯的直接和后续影响,并促进每年该计划的改进。通过一系列的活动,我们希望向学生们灌输 一生专注于学术活动和对肾脏的兴趣。
英文摘要
DESCRIPTION (provided by applicant): The Harvard Summer Research Program in Kidney Medicine is designed to introduce talented undergraduate students to the rich and exciting world of kidney research. The core feature of the proposed program is an intensive research experience under the guidance of experienced and committed investigators from the Harvard Medical School faculty. The research activities may be bench science or clinical research. Projects will be based at one of four major Harvard affiliated research institutions: Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Massachusetts General Hospital and Boston's Children's Hospital. Participation of each site will be facilitated by "site miners", key research faculty at that institution who will help match students with research opportunities. The Nephrology Division chiefs will ensure institutional commitment and support. Each site has committed to taking at least 4 students per summer. Students will also participate in a core curriculum that will include two central components: 1) an introduction to the principles of renal physiology and basic mechanisms of disease and how disease affects real patients; 2) training in evaluation of individuals for chronic kidney disease and an opportunity to participate in a community screening effort, sponsored by our Kidney Disease Screening and Awareness Program. An additional goal of the core curriculum is to promote student interest and confidence to pursue a career in the sciences. Students will receive training in fundamental aspects of experimental design and implementation. Social activities will complement formal aspects of the Program to enhance students' understanding of the community of research and the joy of discovery. Individual preceptors at each institution will help students to prepare for local presentations of their research. Students will also participate in the signature science symposium that is planned by the NIDDK in Bethesda, MD, to culminate this intensive experience. The program leadership will consist of a Director and two Associate Directors, each of whom has had significant experience in guiding the careers of many trainees at various stages of development, including college undergraduate students. Both internal and external oversight committees have been constructed to optimize the effectiveness of the Program, optimize matching of students to research mentor and advise and mentor students on career choices. In addition, an assessment component has been devised to determine the Program's immediate and subsequent impact on the participants' careers and to facilitate improvement of the Program each year. With this range of activities in place, we hope to instill in the students a lifetime focus on scholarly activities and an interest in the kidney.
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Engineering RNA editing tools for the generation of functional tRNA-derived small RNAs in the kidney
  • 批准号:
    10751516
  • 项目类别:
  • 资助金额:
    $33.18万
  • 财政年份:
    2023
  • 负责人:
    JOSEPH VINCENT BONVENTRE
  • 依托单位:
Kidney Microphysiological Analysis Platforms (MAP) to Optimize Function and Model Disease
  • 批准号:
    10018126
  • 项目类别:
  • 资助金额:
    $100.61万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH VINCENT BONVENTRE
  • 依托单位:
Kidney Microphysiological Analysis Platforms (MAP) to Optimize Function and Model Disease
  • 批准号:
    10226203
  • 项目类别:
  • 资助金额:
    $100.61万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH VINCENT BONVENTRE
  • 依托单位:
海外基金