Technical

摘要Tech-1 技术部分1描述了现有定制软件的基本工作。这 这项工作将为Xenbase数据库添加新的功能，并允许我们表示 解剖学和基因表达表型从爪蟾实验使用EQ 语法以及GO注释。这些目标将通过软件实现 Xenbase系统的多个级别的开发，从构建数据库 对表型的支持一直到用户界面。为了建造这个，我们将使用 来自其他MOD的逻辑，比如Xenabse使用GMOD/Chado模式，我们将 调整我们已经为gene建立的web应用程序和接口代码 表情我们经验丰富的开发团队，沿着在此概述的新员工 该提案将在2年的时间内将表型表示构建到Xenbase中。我们 将增加表型的表示，作为基因表达水平的变化， 又是一年添加内容并与外部资源协作， 这些数据对理解人类疾病的分子基础的影响将需要一个 额外的2年。

Summary Tech-1 Technology Component 1 describes essential work on existing custom software. This work will add new functionality to the Xenbase database and allow us to represent both anatomical and gene expression phenotypes from Xenopus experiments using an EQ syntax as well as with GO annotations. These aims will be achieved though software development at multiple levels of the Xenbase system, from building the database support for phenotypes all the way through to user interfaces. To build this we will use logic from other MODs, that like Xenabse use a GMOD/Chado schema and we will adapt the web-application and interface code that we have already established for gene expression. Our experienced development team, along with the new hires outlined in this proposal, will build phenotype representation into Xenbase in a 2 year time frame. We will add representation of phenotypes as changes in gene expression levels within another year. Adding content and collaborating with external resources to maximize the impact of these data in understanding the molecular basis of human disease will take an additional 2 years.