CSHL 2019 Microbial Pathogenesis and Host Response Conference

微生物致病机理和宿主反应 2019年9月10日至14日 第十二届微生物发病机制和宿主反应国际会议将重点讨论 跨学科的方法来研究传染病，整合分子微生物学学科， 真核细胞生物学、免疫学和基因组学。微生物疾病再次成为重要的 由于新的病原体的出现，常见病毒的重新上升， 病原体和广泛的耐药性。在人类健康之外，毁灭性的流行病正在破坏稳定 生态系统，棕色蝙蝠和两栖动物目前处于极端威胁之下。会议将提供一个在- 深入关注正在被用来阐明细菌和真菌的机制的方法， 发病机制，并促进这些概念的应用，以控制和 传染病的干预。口头和海报会议将侧重于微生物的主要新兴主题 致病机理和宿主反应，包括：微生物疾病的发病机理和演变; 发病机制的调节，病原体的异质性作为适应机制，宿主细胞/病原体 相互作用，以及病原体逃避先天免疫的策略的多样性。会议将整合 细菌和真菌病原体的研究。口头会议将开始与2-3邀请会谈，由建立 在该领域的领导人，其次是几个较短的会谈选择提交的摘要。广泛的主题， 个别会议包括：1）病原体合并感染; 2）感染的细胞生物学; 3）病原体的异质性 和疾病结果; 4）先天免疫的病原体逃避策略的多样性; 5）微生物 进化和毒力; 6）胃肠道生态学和微生物致病性。纳入两 海报会议以及分配充足的时间为问题后，每个讲座将鼓励 与会者进行了广泛的讨论。会议规模将足够小（300 - 400名科学家）， 促进这些互动，但足够大，以允许口头介绍，不仅从建立 调查人员，但也从初级调查人员和那些具有新颖的观点。一个广泛的整合 细菌和真菌致病机理的各个方面与宿主对病原体的反应有关， 新的跨学科的相互作用，很少实现在其他会议上的微生物发病机制， 要么关注范围更窄，要么过于多样化，以至于难以整合主题。所得 跨学科的互动将促进概念和实验方法的发展， 否则是不可能的

Microbial Pathogenesis and Host Response September 10 - 14, 2019 The twelfth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis & evolution of microbial diseases; the regulation of pathogenesis, heterogeneity of pathogens as an adaptive mechanism, host cell/pathogen interactions, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: 1) pathogen coinfections; 2) cell biology of infections; 3) heterogeneity in pathogen and disease outcomes; 4) the diversity of pathogen evasion strategies of innate immunity; 5) microbial evolution and virulence; and 6) gastrointestinal ecology and microbial pathogenesis. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (300 - 400 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.