2019 CSHL Conference on Biology of Cancer: Microenvironment and Metastasis

2019 CSHL癌症生物学会议：微环境与转移

• 批准号: 9763232
• 负责人: DAVID J. STEWART
• 金额: $ 0.7万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9763232
• 关键词: Archives; Area; Atmosphere; Biochemistry; Biological Models; Biophysics; Biotechnology; Cancer Biology; Cell Communication; Cells; Cellular Metabolic Process; Cellular biology; Child; Clinic; Collaborations; Communities; Consultations; Data; Development; Diagnostic; Disease; Disease Progression; Disease Resistance; Drug Industry; Ensure; Environment; Epigenetic Process; Europe; Faculty; Fostering; Funding; Genetic; Goals; Heterogeneity; Hypoxia; Image; Immune; Immune system; Immunology; International; Investigation; Japan; Laboratories; Malignant Neoplasms; Medicine; Metabolic; Metabolism; Neighborhoods; Neoplasm Metastasis; New York; Non-Malignant; Oral; Organ; Participant; Peer Review; Physiology; Play; Postdoctoral Fellow; Process; Research; Research Institute; Research Personnel; Role; Scientist; Senior Scientist; Signal Transduction; Stromal Cells; Systems Biology; Therapeutic; Thinking; Tumor Biology; Tumor Cell Biology; Woman; Work; base; cancer cell; cancer initiation; cancer therapy; care systems; cell type; drug development; exosome; graduate student; imaging modality; improved; interest; lectures; meetings; member; minority scientist; mouse model; neoplastic cell; next generation; novel therapeutics; personalized cancer therapy; posters; prevent; response; role model; skills; social; success; symposium; therapy resistant; tumor; tumor heterogeneity; tumor microenvironment; tumorigenesis

Biology of Cancer: Microenvironment & Metastasis Cold Spring Harbor, New York September 24 – 28, 2019 ABSTRACT Cancer is now recognized as an abnormal organ where multiple cell types cooperate during cancer initiation and metastatic progression. Enormous progress has been made on identifying genetic, epigenetic and metabolic alterations in tumor cells and characterizing the different cell types composing a tumor, understanding the mechanisms by which these cell types interact with each other, developing ways to image the changes in a tumor and exploring therapeutic opportunities that take into account the non-malignant cells. Thus, there is an emergence of a need for an integrative approach for controlling cancer. However, most cancer meetings are organized to focus on one or two aspects of the many aspects of the biology of tumor. The proposed meeting takes an integrative approach to create a platform and bring together world leaders in different aspects of cancer biology, genetics, epigenetics, metabolism, signaling, immunology, diagnostics, and therapeutics to discuss the latest findings and promote dialogue aimed at solving the chief problems that prevent durable responses in the clinic. We believe that such an integrative approach will certainly trigger discussions and interactions that cross the disciplinary borders and find new ways to develop and deliver novel therapeutic strategies for controlling cancer. The fifth rendition of this biennial conference will draw participants from academic labs, research institutes and biotech/pharmaceutical industries, and will include leaders in the field, established investigators, junior faculty, postdoctoral fellows, graduate students and corporate scientists. To ensure the presentation of the most cutting edge results many speakers will be chosen based on the quality of abstracts submitted to the meeting coordinators and session chairs several months prior to the meeting. To maximize broad participation, efforts have been made to include outstanding women scientists and scientists from abroad as session chairs and invited speakers. Each session will be chaired by two leading scientists in the field selected by the organizers. Oral presentations will be selected from submitted abstracts by the session chairs in consultation with the organizers. Selected speakers will include graduate students, postdoctoral fellows and junior faculty aiming for maximal inclusion of young investigators. Of special importance are the two poster sessions and panel discussion. The poster session provide an opportunity for many participants to present their work in an atmosphere conducive to informal discussion and the panel discussion engages thought leaders and the participants on one highly debated topic on the role played by personalized cancer medicine in improving cancer treatment. The meeting will be of moderate size and we expect about 300 people to attend, the vast majority of whom will be presenting a poster or talk.

癌症生物学：微环境与转移 纽约冷泉港 2019年9月24日至28日 摘要 癌症现在被认为是一种异常的器官，其中多种细胞类型在肿瘤发生时相互作用。 癌症起始和转移进展。在确定 肿瘤细胞中的遗传、表观遗传和代谢改变，并表征不同细胞 组成肿瘤的细胞类型，了解这些细胞类型相互作用的机制 相互合作，开发肿瘤变化的成像方法，探索治疗方法， 考虑到非恶性细胞的机会。因此，出现了一个 需要一种综合的方法来控制癌症。然而，大多数癌症会议 有组织地集中在肿瘤生物学的许多方面中的一个或两个方面。的 拟议的会议采取综合办法，建立一个平台， 癌症生物学、遗传学、表观遗传学、代谢、信号传导、 免疫学，诊断学和治疗学，讨论最新发现并促进对话 旨在解决临床上阻止持久反应的主要问题。我们认为 这种综合办法肯定会引发跨区域的讨论和互动， 学科边界，并找到新的方法来开发和提供新的治疗策略， 控制癌症 这个两年一度的会议的第五次演出将吸引来自学术实验室，研究 研究所和生物技术/制药行业，并将包括在该领域的领导者，建立 研究人员、初级教员、博士后研究员、研究生和企业科学家。到 确保最前沿的结果，许多发言者将被选择的基础上介绍 关于提交给会议协调员和会议主席的摘要的质量， 会议前几个月。为了最大限度地扩大参与，已作出努力， 杰出女科学家和国外科学家担任会议主席，并邀请 扬声器.每次会议将由该领域的两名顶尖科学家主持， 组织者.口头报告将从会议主席提交的摘要中选出 与组织者协商。选定的演讲者将包括研究生， 博士后研究员和初级教师，旨在最大限度地纳入年轻的研究人员。的 特别重要的是两个海报会议和小组讨论。论文展讲会 为许多与会者提供了一个机会，使他们能够在一个有利的气氛中介绍自己的工作， 非正式讨论和小组讨论吸引思想领袖和参与者 关于个性化癌症药物在改善癌症患者的 癌症治疗会议将是中等规模，我们预计约300人， 参加，其中绝大多数将提交海报或演讲。