Retail Meat Surveillance in the State of Kansas as a Part of the National Antimicrobial Resistance Monitoring System

堪萨斯州零售肉类监测作为国家抗菌素耐药性监测系统的一部分

• 批准号: 9768178
• 负责人: Tiruvoor G Nagaraja
• 金额: $ 15.5万
• 依托单位: KANSAS STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9768178
• 关键词: Retail; Meat; Surveillance; State; Kansas

Project Summary Retail Meat Surveillance in the State of Kansas as a Part of the National Antimicrobial Resistance Monitoring System As a key activity in combating antimicrobial resistance, the National Antimicrobial Resistance Monitoring System (NARMS) conducts surveillance of resistance in foodborne pathogens and other enteric bacteria of food animals at the time of animal processing, in meat and poultry in retail, and in human foodborne infections. The retail food surveillance is coordinated by the Food and Drug Administration (FDA) and in 2015 included 14 of the U.S. mainland states. The goal of this project is to extend the retail food surveillance activities to Kansas, one of the major food animal producing states of the nation. The enhanced retail food surveillance method used by the NARMS since 2015 will be implemented in Kansas. Eighty meat and poultry products from retail stores in the state will be sampled monthly. To accurately reflect exposure of the state's population to resistance in food, the sampling will be stratified to use randomly selected stores in most, moderately and least populated areas, with the sampling intensity in each area type proportional to percentage of the state's population residing there. Each of the meat and poultry samples will be analyzed for presence of Salmonella spp., Escherichia coli, and Enterococcus spp.; poultry samples also for Campylobacter spp. Epidemiological data about the production, origin, packaging, and retailing of the meat and poultry sampled will be collated and provided to the NARMS. The bacterial isolates will be subjected by the FDA to tests for antimicrobial resistance and other epidemiologically-relevant tests (e.g., Salmonella serotyping, Campylobacter speciation). The results will be used by the NARMS to enhance resistance surveillance and foodborne outbreak analysis at the national level. The results will also be returned to Kansas where they will be integrated with data on human foodborne infections, to support analysis of foodborne outbreaks by the state public health authorities, and guide public health action. The results will be delivered to clinicians to inform antimicrobial stewardship in treating foodborne infections. The results will further be innovatively used in the state to integrate data on resistance in the food animal populations, retail food, and humans. The integrated data will be analyzed to advance understanding of resistance dynamics between the animals, food, and humans. This project will strengthen surveillance and analysis of antimicrobial resistance, support foodborne outbreak analysis, and thus promote public health in Kansas and nation-wide.

项目摘要 堪萨斯州作为国家肉类零售监测的一部分 抗菌药物耐药性监测系统 作为抗菌素耐药性的一项关键活动，国家抗菌素 耐药性监测系统(NARMS)在 食用动物出栏时的食源性致病菌和其他肠道细菌 在肉类和家禽零售中，以及在人类食源性感染中。零售业 食品监测由食品和药物管理局(FDA)和 2015年包括美国大陆的14个州。该项目的目标是扩展 对主要食用动物生产州之一堪萨斯州的零售食品监测活动 国家的国家。NARMS使用的强化零售食品监测方法 自2015年起将在堪萨斯州实施。零售的80种肉类和家禽产品 该州的商店将每月进行抽样。以准确反映该州的 对于对食物产生抗性的人群，将采用分层抽样的方法随机抽取 商店位于人口最多、中等和最少的地区，抽样强度为 每个区域类型与该州居住在那里的人口的百分比成比例。每个人 的肉类和家禽样本将进行沙门氏菌检测， 大肠埃希氏菌和肠球菌；家禽样本也用于弯曲杆菌。 有关肉类生产、来源、包装和零售的流行病学数据 并将对采样的家禽进行整理并提供给NARMS。细菌分离株 将接受FDA的抗菌素耐药性测试和其他 流行病学相关检测(例如，沙门氏菌血清分型、弯曲杆菌 物种形成)。结果将被NARMS用来加强耐药性监测 以及国家一级的食源性暴发分析。结果也将被返回 到堪萨斯州，在那里他们将与人类食源性感染的数据相结合， 支持国家公共卫生当局对食源性疫情的分析，并指导 公共卫生行动。结果将被提供给临床医生，以告知抗菌药物 在治疗食源性感染方面的管理。研究成果将进一步创新应用 在该州整合食用动物种群、零售食品、 和人类。将对综合数据进行分析，以增进对 动物、食物和人类之间的抗性动态。这个项目将 加强抗菌素耐药性监测分析，支持食源性疾病 疫情分析，从而促进堪萨斯州和全国的公共卫生。