Emory-Nigeria HIV Research Training Program (EN-RTP)

在全世界和许多撒哈拉以南非洲国家的3670万艾滋病毒感染者中， 在包括尼日利亚在内的非洲国家，每3名感染艾滋病毒的成年人中就有2名是妇女。更令人担忧的是， 观察到尼日利亚绝大多数新感染者是年轻育龄妇女 因此，全球三分之一的母婴传播艾滋病毒病例发生在该国。不 尽管妇女的艾滋病毒负担更重，但其祸害的影响要深远得多。艾滋病毒是主要的 这是尼日利亚育龄妇女发病率和死亡率的主要原因。艾滋病毒使各个方面都变得复杂 妇女一生中的健康状况，包括生殖健康，因为它影响到伴侣的血清分类， 性习惯、生育欲望和避孕选择、怀孕和分娩、更年期和衰老。 应对感染艾滋病毒的妇女所面临的无数健康挑战是实现以下目标的必要步骤： 卫生组织妇女、儿童和青少年健康全球战略。这需要培养一批 当地卫生科学家，并使他们具备进行有效研究的技能， 妇女艾滋病毒感染者的健康需求。 为了开始满足这些需求，我们将利用埃默里大学的研究教育基础设施， 尼日利亚合作机构（尼日利亚医学研究所;拉各斯大学 （UNILAG）和尼日利亚艾滋病预防倡议（APIN））提供最先进的国内研究 培训重点是方法、严格的指导和赠款管理能力建设。等 培训将应用于艾滋病毒/妇女健康研究的三个主要领域：a）艾滋病毒预防和 生殖健康; B）感染艾滋病毒的妇女在艾滋病毒治疗方面面临的独特挑战;以及c） 与WLWH相关的慢性HIV感染并发症。根据他们在以下方面的专业知识来选择辅导员： 这些领域和他们的指导经验。

Women comprise about 50% of the 36.7 million people living with HIV worldwide and in many sub-Saharan African countries including Nigeria, ~2 out of 3 HIV infected adults are women. Even more worrisome is the observation that overwhelming number of new infections in Nigeria occur among young women of childbearing age, and as such, one-third of all global cases of mother-to-child transmission of HIV occurs in the country. Not only is the burden of HIV higher in women, the impact of its scourge is far more reaching. HIV is the leading cause of morbidity and mortality among women of reproductive age in Nigeria. HIV complicates every aspect of health across a woman’s lifespan, including reproductive health where it impacts partner sero-sorting and sexual habits, fertility desires and contraceptive choices, pregnancy and delivery, menopause and aging. Tackling the myriads of health challenges confronting women living with HIV is a necessary step to achieving the WHO global strategy for women’s, children’s and adolescent health. It will require nurturing a critical mass of local health scientists and equipping them with the skills to conduct valid research that addresses the local health needs of women living with HIV. To begin to meet these needs, we will leverage the research education infrastructure at Emory University and the partnering Nigerian institutions (Nigerian Institute of Medical Research (NIMR); University of Lagos (UNILAG); and AIDS Prevention Initiative Nigeria (APIN)) to provide state-of-the-art in-country research training with focus on methodologies, rigorous mentorship, and grant management capacity building. Such training will be applied to three main domains of HIV/women’s health research: a) HIV prevention and reproductive health; b) Challenges in HIV therapeutics unique to women living with HIV (WLWH); and c) Complications of chronic HIV infection relevant to WLWH. Preceptors are selected based on their expertise in these areas and their mentoring experience.