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Research Education Component (REC)

Research Education Component (REC)
研究教育部分(REC)
批准号:
9922634
负责人:
Hussein N Yassine
金额:
$10.26万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-09-01 至 2025-02-28

项目摘要

项目成果

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中文摘要
翻译
摘要:研究教育组成部分(REC) 南加州大学阿尔茨海默病研究中心的使命 (ADRC)研究教育核心(REC)是从 从事阿尔茨海默病和相关痴呆症(ADRD)研究的不同学科 总的来说,强调影响ADRD的与年龄相关的血管/代谢过程 洛杉矶县拉丁裔人口的风险。肥胖、糖尿病、血脂异常和 在拉丁裔社区中,高血压的发病率高得不成比例。这些 代谢和血管危险因素也与AD发病率的增加有关 以及与年龄相关的认知能力下降。然而,很少有干预措施被设计成针对 这些人群特有的风险因素。我们建议将REC培训计划的重点放在 通过利用现有研究计划来关注Latinx老年人大脑健康的领域,请访问 南加州大学专注于少数民族中的AD风险。为了实现我们的目标,我们已经与几家 ADRD和老龄化培训计划,积极吸引来自代表性不足民族的科学家 我们的目标是将这些团体整合到我们的计划中。我们有三个具体目标。第一,支持 ADRC科学家通过多学科培训计划、试点资金和年度 研讨会。第二,支持最多三名博士后研究人员的职业发展 来自代表不足的少数族裔研究人员,他们表现出了非凡的职业前景 南加州大学教务处赞助的为期两年的博士后奖学金。第三,监督 ADRC科学家在获奖期间以及在其早期职业生涯中的进展 里程碑(例如,收到独立赠款)。亚洲发展研究中心的科学家校友将在 继续参与支持和改善他们的职业选择和 下一批试点受赠人的经验。
英文摘要
Abstract: Research Education Component (REC) The mission of the University of Southern California (USC) Alzheimer’s disease research center (ADRC) Research Education Core (REC) is to direct the scientific careers of scientists from diverse disciplines into a career in Alzheimer’s disease and related dementias (ADRD) research in general, and an emphasis on age-associated vascular/metabolic processes that affects ADRD risk in the Latinx population in Los Angeles County. Obesity, diabetes, dyslipidemia and hypertension have been found at disproportionally high rates in Latinx communities. These metabolic and vascular risk factors have also been associated with an increased AD incidence and age-related cognitive decline. However, very few interventions have been designed to target the risk factors specific to these populations. We propose to center our REC training program on areas that are focused on Latinx elderly brain health by leveraging existing research programs at USC focused on AD risk in ethnic minorities. To achieve our aims, we have partnered with several ADRD and Aging training programs that actively engage scientists from under-represented ethnic groups that we aim to integrate into our program. We have three Specific Aims. First, support ADRC scientists through multidisciplinary training program, pilot funding and an annual symposium. Second, support the career development of up to three post-doctoral investigators from under-represented minority researchers who have shown remarkable professional promise for a 2-year post-doctoral fellowship sponsored by the USC provost office. Third, monitor the progress of ADRC scientists during the period of the award as well as through their early career milestones (e.g., receipt of an independent grant). ADRC scientist alumni will be supported in continued involvement in activities that support and improve both their career options and the experience of the next cohort of pilot grantees.
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会议论文
The delivery of essential fatty acids to the Brain in Alzheimer's disease
  • 批准号:
    10425137
  • 项目类别:
  • 资助金额:
    $112.98万
  • 财政年份:
    2021
  • 负责人:
    Hussein N Yassine
  • 依托单位:
Research Education Component (REC)
  • 批准号:
    10247462
  • 项目类别:
  • 资助金额:
    $15.42万
  • 财政年份:
    2020
  • 负责人:
    Hussein N Yassine
  • 依托单位:
ApoE, ABCA1 and endosomal dysregulation in AD
  • 批准号:
    10565880
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2020
  • 负责人:
    Hussein N Yassine
  • 依托单位:
ApoE, ABCA1 and endosomal dysregulation in AD
  • 批准号:
    10164697
  • 项目类别:
  • 资助金额:
    $75.18万
  • 财政年份:
    2020
  • 负责人:
    Hussein N Yassine
  • 依托单位:
国内基金
海外基金
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  • 项目类别:
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对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
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  • 项目类别:
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AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
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  • 项目类别:
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  • 负责人:
    万荣
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