Research Education Component (REC)

研究教育部分（REC）

基本信息

批准号：
10247462
负责人：
Hussein N Yassine
金额：
$ 15.42万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-01 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10247462
关键词：
Affect Age Age-associated memory impairment Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Alzheimer&apos s disease therapeutic Area Award Biometry Blood Vessels Body Weight decreased California Clinical Trials Cognitive Collaborations Communities County Data Decision Making Demography Diabetes Mellitus Discipline Dyslipidemias Economics Education Elderly Environment Ethnic group Exercise Exposure to Faculty Family Fellowship Funding Gerontology Goals Grant Health Health Policy Healthcare Hypertension Image Incidence Institutes Interdisciplinary Study Intervention Investigator-Initiated Research Latinx Life Style Los Angeles Medicine Mentors Mentorship Metabolic Metabolism Minority Mission Monitor Multimodal Imaging Neuropsychology Obesity Population Population Research Postdoctoral Fellow Psychometrics Publishing Research Research Institute Research Personnel Research Project Grants Resources Risk Risk Factors Scientist Secure Social Work Sociology Targeted Research Testing Tissue Sample Training Training Programs Underrepresented Minority Universities academic program age related base brain health career career development clinical center cohort computer science dementia risk design education research ethnic minority population experience health care economics human old age (65+)improved medical schools multidisciplinary programs recruit simulation social success symposium translational genomics vascular risk factor

项目摘要

Abstract: Research Education Component (REC) The mission of the University of Southern California (USC) Alzheimer’s disease research center (ADRC) Research Education Core (REC) is to direct the scientific careers of scientists from diverse disciplines into a career in Alzheimer’s disease and related dementias (ADRD) research in general, and an emphasis on age-associated vascular/metabolic processes that affects ADRD risk in the Latinx population in Los Angeles County. Obesity, diabetes, dyslipidemia and hypertension have been found at disproportionally high rates in Latinx communities. These metabolic and vascular risk factors have also been associated with an increased AD incidence and age-related cognitive decline. However, very few interventions have been designed to target the risk factors specific to these populations. We propose to center our REC training program on areas that are focused on Latinx elderly brain health by leveraging existing research programs at USC focused on AD risk in ethnic minorities. To achieve our aims, we have partnered with several ADRD and Aging training programs that actively engage scientists from under-represented ethnic groups that we aim to integrate into our program. We have three Specific Aims. First, support ADRC scientists through multidisciplinary training program, pilot funding and an annual symposium. Second, support the career development of up to three post-doctoral investigators from under-represented minority researchers who have shown remarkable professional promise for a 2-year post-doctoral fellowship sponsored by the USC provost office. Third, monitor the progress of ADRC scientists during the period of the award as well as through their early career milestones (e.g., receipt of an independent grant). ADRC scientist alumni will be supported in continued involvement in activities that support and improve both their career options and the experience of the next cohort of pilot grantees.

摘要：研究教育部分（REC）南加州大学（USC）阿尔茨海默氏病研究中心的任务（ADRC）研究教育核心（REC）是指导科学家的科学职业潜水员学科进入阿尔茨海默氏病和相关痴呆症（ADRD）研究的职业通常，强调影响ADRD的年龄相关的血管/代谢过程洛杉矶县拉丁裔人口的风险。肥胖，糖尿病，血脂异常和在拉丁裔社区中，已经发现高血压的比例高。这些代谢和血管危险因素也与广告发病率增加有关和与年龄有关的认知下降。但是，很少有人设计干预措施来针对目标这些人群的风险因素。我们建议将我们的Rec培训计划集中通过利用现有的研究计划，专注于拉丁裔的领域 USC专注于少数民族的AD风险。为了实现我们的目标，我们与几个 ADRD和老化的培训计划，积极吸引人物不足的种族的科学家我们旨在融入计划的小组。我们有三个具体的目标。首先，支持 ADRC科学家通过多学科培训计划，试点资金和年度座谈会。其次，支持多达三位博士后调查人员的职业发展来自代表性不足的少数族裔研究人员，他们表现出了非凡的专业诺言由USC Provost办公室赞助的2年后奖学金。第三，监视 ADRC科学家在奖项期间以及他们的早期职业生涯中的进步里程碑（例如，收到独立赠款）。 ADRC科学家校友将得到支持继续参与支持和改善其职业选择和改善其职业选择的活动和下一个飞行员格兰德斯队的经验。