Research Education Component (REC)

研究教育部分（REC）

• 批准号: 10655671
• 负责人: Hussein N Yassine
• 金额: $ 19.98万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655671
• 关键词: Affect; Age; Age-associated memory impairment; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease therapeutic; Area; Award; Biometry; Blood Vessels; Body Weight decreased; California; Clinical Trials; Collaborations; Communities; County; Data; Decision Making; Demography; Diabetes Mellitus; Discipline; Dyslipidemias; Economics; Education; Elderly; Environment; Ethnic Population; Exercise; Exposure to; Faculty; Family; Fellowship; Funding; Gerontology; Goals; Grant; Health; Health Policy; Healthcare; Hypertension; Image; Incidence; Interdisciplinary Study; Intervention; Investigator-Initiated Research; Latinx; Latinx population; Life Style; Los Angeles; Medicine; Mentors; Mentorship; Metabolic; Metabolism; Minority Health Research; Mission; Monitor; Multimodal Imaging; Neuropsychology; Obesity; Population; Population Research; Postdoctoral Fellow; Psychometrics; Publishing; Research; Research Institute; Research Personnel; Research Project Grants; Resources; Risk; Risk Factors; Scientist; Secure; Social Work; Sociology; Targeted Research; Testing; Tissue Sample; Training; Training Programs; Underrepresented Minority; Universities; academic program; brain health; career; career development; clinical center; cohort; computer science; dementia risk; design; education research; ethnic minority; experience; human old age (65+); improved; medical schools; minority investigator; multidisciplinary; postdoctoral investigator; programs; recruit; simulation; social; success; symposium; translational genomics; vascular risk factor

Abstract: Research Education Component (REC) The mission of the University of Southern California (USC) Alzheimer’s disease research center (ADRC) Research Education Core (REC) is to direct the scientific careers of scientists from diverse disciplines into a career in Alzheimer’s disease and related dementias (ADRD) research in general, and an emphasis on age-associated vascular/metabolic processes that affects ADRD risk in the Latinx population in Los Angeles County. Obesity, diabetes, dyslipidemia and hypertension have been found at disproportionally high rates in Latinx communities. These metabolic and vascular risk factors have also been associated with an increased AD incidence and age-related cognitive decline. However, very few interventions have been designed to target the risk factors specific to these populations. We propose to center our REC training program on areas that are focused on Latinx elderly brain health by leveraging existing research programs at USC focused on AD risk in ethnic minorities. To achieve our aims, we have partnered with several ADRD and Aging training programs that actively engage scientists from under-represented ethnic groups that we aim to integrate into our program. We have three Specific Aims. First, support ADRC scientists through multidisciplinary training program, pilot funding and an annual symposium. Second, support the career development of up to three post-doctoral investigators from under-represented minority researchers who have shown remarkable professional promise for a 2-year post-doctoral fellowship sponsored by the USC provost office. Third, monitor the progress of ADRC scientists during the period of the award as well as through their early career milestones (e.g., receipt of an independent grant). ADRC scientist alumni will be supported in continued involvement in activities that support and improve both their career options and the experience of the next cohort of pilot grantees.

翻译后摘要：研究教育组件（REC） 南加州大学阿尔茨海默病研究中心的使命 （ADRC）研究教育核心（REC）是指导科学家的科学生涯， 阿尔茨海默病和相关痴呆症（ADRD）研究的职业生涯 一般而言，强调与年龄相关的影响ADRD的血管/代谢过程 洛杉矶县拉丁裔人群的风险。肥胖、糖尿病、血脂异常和 高血压在拉丁裔社区发病率高得惊人。这些 代谢和血管危险因素也与AD发病率增加有关 以及与年龄相关的认知能力下降然而，很少有干预措施是针对 这些人群特有的风险因素。我们建议将我们的REC培训计划集中在 这些领域通过利用现有的研究项目，专注于拉丁裔老年人的大脑健康， 南加州大学的重点是少数民族的AD风险。为了实现我们的目标，我们与几个 ADRD和老龄化培训计划，积极吸引来自代表性不足的种族的科学家 我们的目标是将其纳入我们的计划。我们有三个具体目标。一是支持 ADRC科学家通过多学科培训计划，试点资金和年度 研讨会第二，支持最多3名博士后研究人员的职业发展 来自少数族裔研究人员，他们表现出非凡的专业前景， 南加州大学教务长办公室赞助的为期两年的博士后研究金。第三，监督 ADRC科学家在获奖期间以及他们早期职业生涯中的进步 里程碑（例如，获得独立资助）。ADRC科学家校友将得到支持， 继续参与支持和改善他们的职业选择和就业机会的活动， 下一批试点受赠方的经验。