Enabling advancement in 3D printing for dentistry through high-performance materials, new processing techniques and comprehensive metrics

通过高性能材料、新加工技术和综合指标，推动牙科 3D 打印的进步

基本信息

批准号：
9975164
负责人：
JEFFREY W. STANSBURY
金额：
$ 18.82万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-09 至 2022-06-30
项目状态：
已结题

项目摘要

The expansion in photocure-based additive manufacturing has been stunning and it represents a rare, truly disruptive technological advancement. The ability to rapidly produce customized models and functional parts to at least some degree, as well as enabling the transition toward digital rather than physical inventories is incredibly attractive. However, full realization of the potential promises of 3D printing is reliant on the sustained improvement in the materials and the processes used. There is a significant gap in the accessible performance spectrum of 3D printed parts where final material properties can be achieved that combine both high modulus/strength and high toughness. We are seeking to deliver a step-change in the performance potential of 3D printable materials in terms of robust, isotopic mechanical properties, greatly enhanced resolution and printing accuracy. Additional aspects deal with improved characterization of 3D printed materials that can apply to both existing formulations and particularly to highlight how the proposed lack of monomer migration into and within parts as they are being printed affects the final properties obtained. There are two specific Aims guiding this project. The first Aim involves the complementary coupling of two proven innovative approaches developed independently by the PI: 1) extremely high strength and high toughness photopolymers that match or even exceed the mechanical performance properties of engineering plastics that cannot be photo-processed in combination with 2) reactive nanogel additives that contribute significant network-like structure ahead of polymerization and the unique potential for continued post cure that remains spatially isolated only within the photo-exposed regions to yield extremely high resolution patterned structures. These features when combined, address several of the current limitations associated with 3D printing. The second Aim uses sophisticated analytical tools and models as well as printing and post-printing processes that will extend understanding of the complexities of photopolymer-based 3D printing. Our goal is to provide access to markedly higher performance and high resolution 3D printing materials that open opportunities for practical in-lab or even in-office production of fully functional printed crowns, bridges, dentures, and other intraoral prosthetics. These materials would also enhance the already growing dental market for orthodontic aligners, bite splints and even for higher resolution dental models while undoubtedly opening additional application areas not currently available due to an unmet need for higher performance materials. We can demonstrate that our baseline materials significantly outperform conventional dental materials and current 3D printed products. Providing a practical solution to the existing challenges that are impeding the logical transition of digital dentistry into printer-based clinical services, is the basis for this proposed project. The advances made here are also expected to resonate throughout the multitude of application areas that are becoming increasingly reliant on 3D printing as the performance of available materials improve.

基于光的添加剂制造的扩展令人惊叹，它代表了一种罕见的，真正的破坏性技术进步。迅速生产自定义模型和功能零件至少在某种程度上的能力，以及使向数字而非实体库存的过渡非常有吸引力。但是，满实现3D打印的潜在承诺取决于材料和过程的持续改进用过的。 3D打印零件的最终材料属性的可访问性能范围有很大的差距可以实现结合高模量/强度和高韧性的结合。我们正在寻求在从强大的同位素机械性能方面，3D可打印材料的性能潜力大大增强分辨率和打印精度。其他方面涉及改进的3D印刷材料的表征适用于现有的配方，特别是强调拟议中缺乏单体迁移到和在零件中打印的零件会影响获得的最终属性。指导这个项目有两个具体的目标。第一个目的涉及两种由两种经过验证的创新方法独立开发的互补耦合 PI：1）匹配甚至超过机械性能的极高强度和高韧性光聚合物无法与2）反应性纳米凝胶添加剂相结合的工程塑料的特性在聚合和持续后治愈的独特潜力之前，贡献重要的网络状结构仅在光照区域内仅在空间上孤立，以产生极高的分辨率图案结构。这些功能合并后，请解决与3D打印相关的当前限制。第二个目的使用复杂的分析工具和模型以及印刷和后印刷过程，这些过程将扩展对基于光聚合物的3D打印的复杂性。我们的目标是提供明显更高的性能和高分辨率3D打印材料，可以为实用的现场或办公室生产提供全面生产的机会功能印刷的冠，桥梁，假牙和其他口腔内假肢。这些材料也可以增强牙齿牙齿对准器，咬合夹板甚至更高分辨率牙科模型的牙齿市场不断发展由于对更高性能材料的需求未满足，打开其他应用区域。我们可以证明我们的基线材料的表现明显优于常规牙科材料和当前的3D印刷产品。为阻碍数字牙科逻辑过渡的现有挑战提供了实用的解决方案进入基于打印机的临床服务是该拟议项目的基础。预计这里取得的进步在越来越依赖3D打印的整个应用领域中引起共鸣可用材料的性能得到改善。