Multidisciplinary Training in Brain Disorders and Development

这一博士后培训计划的目标是培养年轻科学家，促进专注于 了解并开发治疗发育性大脑疾病的方法。多学科培训是 在与神经发育障碍研究相关的科学学科中进行规划。因此，31个培训 教师是从7个系中挑选出来的。包括：博士5人，博士6人，博士20人。那里 包括：教授16人，副教授9人，助理教授6人。目前有119个 博士后在教研室培训。该培训计划现在的基础是 简和丹·邓肯神经研究所(NRI)，已经成为 对大脑发育异常的研究，并分享了本培训计划的目标。约翰博士 斯旺将继续担任项目总监，负责日常运营 计划的一部分。胡达·佐格比博士将继续担任联席主任。主要培训领域包括 神经发育障碍的遗传和分子基础，包括但不限于：自闭症， 雷特综合征、安吉曼综合征和溶酶体储积症。另一个集中的地区 训练是在癫痫中，研究遗传性和获得性癫痫的分子基础。 这些实验室使用尖端生物技术来研究人类疾病并建立相关的动物模型。 以便不仅了解这些疾病的分子基础，而且筛选潜在的 可能导致临床试验并最终进入临床实践的新疗法。在过去14年中 经过多年的支持，已有38名博士后进入我们的培养计划。从第一个十年开始 在23名受训人员中，有18人(78%)成为主要大学的教员。26% 我们的受训人员中有一半来自多元化团体。其中四人现在是教职员工，两人是 在工业界工作的科学家。我们还培训了5名医学博士/博士儿童神经学家，他们已经 获得了K08奖学金，现在正在从事研究工作。提供三条培训赛道。一个是为了 通过晚餐接受神经发育障碍临床方面实质性培训的博士 讨论、临床会议和专科诊所。另一种是针对医学博士和医学博士的 有丰富的研究经验。研究经验较少的MDS接受更正规的培训， 包括实验室轮换和研究生课程。许多独特的共享培训机会包括 提供给我们的实习生，包括为博士后开设的新研讨会。通过培训优秀的研究人员 科学家们，我们对婴儿破坏性的神经系统疾病有了新的理解和治疗 幼小的孩子将会出现。

The goal of this postdoctoral training program is to train young scientists and promote careers focused on understanding and developing treatments for developmental brain disorders. Multidisciplinary training is planned in scientific disciplines relevant to the study of neurodevelopmental disorders. Thus, 31 training faculty have been selected from 7 departments. They include: 5 MDs, 6 MD/PhDs and 20 PhDs. There are: 16 Professors, 9 Associate Professors and 6 Assistant Professors. There are currently 119 postdoctoral students training in laboratories of the faculty. This training program is now based in the Jan and Dan Duncan Neurological Research Institute (The NRI) which has become a major center for the study of developmental brain abnormalities and shares the goals of this training program. Dr. John Swann will continue to serve as the Program Director and will be responsible for the day-to-day operation of the program. Dr. Huda Zoghbi will continue to serve as co-director. Major areas of training include the genetic and molecular basis of neurodevelopmental disorders including but not limited to: Autism, Rett syndrome, Angelman syndrome and Lysosomal Storage Diseases. Another concentrated area of training is in epilepsy where the molecular bases of the inherited as well as acquired epilepsies are studied. The labs employ cutting edge biotechnology to study human disorders and create relevant animals models of disease in order to not only understand the molecular basis for these disorders but to screen potential new therapies that could lead to clinical trials and eventually enter clinical practice. Over the past 14 years of support, 38 postdoctoral students have entered our training program. From the first 10 years of grant support, 18 of 23 trainees (78%) became faculty members at major universities. Twenty-six percent of our trainees have been from diversity groups. Four of them are now faculty members and 2 are scientists working in industry. We have also trained 5 MD/PhD child neurologists that have been awarded K08 grants and are now pursuing research careers. Three training tracks are offered. One is for PhDs who receive substantial training in clinical aspects of neurodevelopmental disorders through dinner discussions, clinical conferences and subspecialty clinics. Another is for MD/PhDs and MDs with substantial research experience. MDs with little research experience receive more formal training which includes laboratory rotations and graduate courses. A number of unique shared training opportunities are being offered to our trainees including the new Workshops for Postdocs. By training outstanding research scientists, we feel new understandings and treatments for the devastating neurological disorders of infants and young children will emerge.