Leadership Administrative Core - LAC

领导行政核心 - LAC

• 批准号: 10213169
• 负责人: SABRA L. KLEIN
• 金额: $ 20.88万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10213169
• 关键词: Age; Biological; Communities; Development; Educational Curriculum; Educational process of instructing; Ensure; Evaluation; Faculty; Gender; Genes; Goals; Government; Growth; Hormones; Immune response; Immunity; Immunology; Influenza; Information Dissemination; International; Leadership; Life Cycle Stages; Link; Mediating; Mentors; Microbiology; Molecular; Play; Principal Investigator; Professional Organizations; Protocols documentation; Public Health Schools; Publications; Research; Research Personnel; Research Project Grants; Role; Sex Differences; Societies; Structure; Universities; Vaccines; Women' s Health; age difference; career; data dissemination; frailty; influenza virus vaccine; medical schools; meetings; programs; sex; skills; social media; symposium; web site

SEX AND AGE DIFFERENCES IN IMMUNITY TO INFLUENZA (SADII) LEADERSHIP ADMINISTRATIVE CORE SUMMARY The primary goal of the SCORE on Sex and Age Differences in Immunity to Influenza (SADII) is to systematically evaluate sex differences in vaccine-induced immune responses across the life course, with consideration of the role that hormones, genes, age, and frailty play as independent and combined mediating factors. The primary objective of the SADII Leadership Administrative Core (LAC) is to provide centralized management, leadership, rigor, sharing, and dissemination of the data from the proposed Research Projects and Cores in the SADII SCORE. This objective will be met by accomplishing three specific aims. Aim 1 will be to provide a centralized, structured administration for all SADII SCORE investigators. The SADII SCORE will be physically housed within the Department of Molecular Microbiology and Immunology (MMI) at the Johns Hopkins Bloomberg School of Public Health and through the SADII Career Enhancement Core, will be integrated with the Johns Hopkins BIRCWH program and the Johns Hopkins Center for Women’s Health, Sex, and Gender Research (JH-CWHSGR). Aim 2 will be to provide scientific leadership for the SADII SCORE program. The SADII LAC will ensure rigor in the research conducted, dissemination of the research results to the greater scientific community, mentoring of junior faculty new to the study of sex as a biological variable, and integration of the SADII SCORE into the conceptual framework and teachings at Johns Hopkins University. Aim 3 of the SADII LAC will seek to enhance dissemination of research findings from the SADII SCORE to the Johns Hopkins research community, broader scientific community, and governmental decision bodies determining influenza vaccine strains and platforms. Dissemination of research findings from the SADII SCORE will involve diverse platforms, including, but not limited to: 1) presentation and dissemination of results at the annual JH-CWHSGR symposium, national and international meetings of professional societies, and the annual meeting of the Organization for the Study of Sex Differences, which is an international research society, for which Dr. Sabra Klein is President (2018-2020); 2) embedding the concept of sex as a biological variable into the Johns Hopkins graduate and medical school curriculum; 3) establishment of a rigorous publication plan that will ensure that publications of research, ideas, and information derived from the SADII SCORE will appropriately acknowledge SADII for its contribution; 4) development of an informational website for the SADII SCORE that links to other related websites both within and outside of Johns Hopkins; and 5) social media engagement for immediate dissemination of SADII research, presentations, and activities. The Program Director (Dr. Sabra Klein) and Co-Director (Dr. Patricia Gearhart) have the research expertise and leadership skills to ensure that the overarching goals of the SADII SCORE are met and exceeded.

流感免疫力(SADII)领导层的性别和年龄差异 行政核心总结 流感免疫力性别和年龄差异评分(SADII)的主要目标是 系统地评估生命过程中疫苗诱导的免疫反应的性别差异， 关于荷尔蒙、基因、年龄和脆弱作为独立和联合中介作用的思考 各种因素。SADII领导行政核心(LAC)的主要目标是提供集中的 管理、领导、严谨、共享和传播来自拟议研究项目的数据 以及SADII分数中的核心。这一目标将通过实现三个具体目标来实现。目标1将是 为所有SADII成绩调查人员提供集中、结构化的管理。SADII分数将 实际安置在约翰斯的分子微生物学和免疫学系(MMI)内 霍普金斯大学彭博公共卫生学院并通过SADII职业提升核心，将 与约翰霍普金斯BIRCWH计划和约翰霍普金斯妇女健康中心整合， 和性别研究(JH-CWHSGR)。目标2将是为SADII评分提供科学领导 程序。SADII LAC将确保所进行的研究的严谨性，将研究结果传播到 更大的科学界，对新近将性别作为生物变量研究的初级教职员工的指导， 将SADII分数整合到约翰霍普金斯大学的概念框架和教学中 大学。SADII LAC的目标3将寻求加强SADII研究成果的传播 为约翰·霍普金斯大学研究界、更广泛的科学界和政府决策打分 确定流感疫苗毒株和平台的机构。传播SADII的研究成果 SCORE将涉及不同平台，包括但不限于：1)成果的介绍和传播 在JH-CWHSGR年度研讨会、国内和国际专业学会会议上，以及 性别差异研究组织年度会议，这是一个国际研究学会， Sabra Klein博士担任主席(2018-2020年)；2)嵌入性概念作为生物变量 纳入约翰霍普金斯大学研究生和医学院的课程；3)建立严格的出版计划 这将确保从SADII评分中得出的研究、想法和信息的出版物将 适当承认SADII的贡献；4)为SADII开发一个信息网站 链接到约翰·霍普金斯大学内外的其他相关网站的分数；以及5)社交媒体 参与SADII研究、演示和活动的即时传播。该计划 主任(Sabra Klein博士)和联席主任(Patricia Gearhart博士)拥有研究专长和领导力 确保达到和超过SADII评分的首要目标的技能。