Translational Science Training to Reduce the Impact of Alcohol on HIV Infection

减少酒精对艾滋病毒感染影响的转化科学培训

• 批准号: 10223171
• 负责人: Robert L Cook
• 金额: $ 29.35万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10223171
• 关键词: Alcohols; HIV Infections; Training; Translational Research

Creation of a new T32 program in Florida, focused on alcohol and HIV infection, will fulfill a significant need. The state of Florida currently ranks first in new HIV infections per year, second in total HIV/AIDS cases, and third in total US population. Alcohol consumption contributes to poor HIV outcomes and to ongoing HIV transmission, and the relationships between alcohol consumption and HIV can vary by age, gender, ethnicity, and sexual orientation. The University of Florida is an ideal location to host the proposed T32, not only due to its geographic location and access to diverse populations, but also due to our growing NIH-supported alcohol research and infrastructure. The overall objective of this T32 grant is to train and mentor the next generation of researchers who have the skills, knowledge and experience to improve health outcomes in those affected by alcohol and HIV. We need a research task force that is capable of developing and implementing alcohol intervention across diverse populations, who can use novel data systems and sources, and who seek to reduce comorbidities associated with aging. Thus, the specific aims of our training program are to a) deliver an academic curriculum, b) provide outstanding mentoring, c) ensure skills in communication of science, d) provide experience in team science, and e) maximize professionalism and ethical conduct of research. The training program will support up to four pre-doctoral and two post-doctoral trainees at any given time, and several potential candidates have already expressed interest. Trainees will be based in the following academic programs: Epidemiology, Biostatistics, Clinical and Health Psychology, Nursing Science, Health Education and Behavior, and/or the Interdisciplinary Program in Medicine. These programs represent a broad range of health- related disciplines, ensuring trainees will have state of the art training in team science. Our 18 faculty mentors span four colleges and eight departments at UF. Each bring unique skills and expertise related to alcohol and HIV. The training program will ensure appropriate depth in knowledge regarding alcohol, HIV, and three additional focus areas that represent areas of strength in ongoing research at UF: a) health behavior intervention science; b) epidemiology and data science; and c) cognitive science related to aging. The training program will be closely integrated with Southern HIV Alcohol Research Consortium (SHARC), which is supported by over $10 million in ongoing NIAAA funding through 2021. The T32 will be led by three MPIs who each have specific administrative roles, and who will obtain input from an Internal Steering Committee, an Advisory Council, and ongoing program evaluations. UF is an outstanding training environment with many supporting resources, including a pledge to provide an additional $500,000 in overall support to our specific training program. Ultimately, the impact of the training program will be judged by the long-term track record of trainees who complete the training program, which we will monitor over time.

在佛罗里达州创建一个新的T32计划，重点是酒精和艾滋病毒感染，将满足一个重要的需求。 佛罗里达州目前每年新增艾滋病毒感染人数排名第一，艾滋病毒/艾滋病病例总数排名第二， 在美国总人口中排名第三。饮酒会导致不良的艾滋病毒结局和持续的艾滋病毒 传播，饮酒和艾滋病毒之间的关系可能会因年龄、性别、种族、 和性取向。佛罗里达大学是举办拟议中的T32的理想地点，不仅是因为 它的地理位置和接触不同人群的机会，但也要归功于我们日益增长的NIH支持的酒精 研究和基础设施。这项T32基金的总体目标是培训和指导下一代 有技能、知识和经验来改善受影响人群的健康结果的研究人员 酒精和艾滋病毒。我们需要一支能够开发和实施酒精的研究工作组 对不同人群的干预，他们可以使用新的数据系统和来源，并寻求 减少与衰老相关的并发症。因此，我们培训计划的具体目标是：a)提供 学术课程，b)提供出色的指导，c)确保科学交流技能，d) 提供团队科学方面的经验，以及e)最大限度地提高研究的专业性和道德性。这个 培训计划将在任何给定时间支持最多四名博士前和两名博士后实习生，以及 几个潜在的候选人已经表达了兴趣。受训者将以下列学术领域为基础 课程：流行病学、生物统计学、临床和健康心理学、护理学、健康教育和 行为，和/或医学跨学科计划。这些计划代表了广泛的健康- 相关学科，确保学员在团队科学方面接受最先进的培训。我们的18位教职员工导师 横跨加州大学的四个学院和八个系。每一个都带来了与酒精有关的独特技能和专业知识 爱滋病毒。培训计划将确保对酒精、艾滋病毒和三种疾病的知识有适当的深度 代表UF正在进行的研究的优势领域的其他重点领域：a)健康行为 干预科学；b)流行病学和数据科学；以及c)与老龄化有关的认知科学。培训 该计划将与南方艾滋病毒酒精研究联盟(SHARC)密切结合，SHARC是 到2021年，NIAAA正在提供1000多万美元的资金支持。T32将由三名MPI领导，他们 每个人都有特定的行政职责，并将从内部指导委员会、 咨询委员会，以及正在进行的项目评估。UF是一个出色的培训环境，拥有许多 支持资源，包括承诺额外提供500,000美元的总体支持，以支持我们的具体项目 培训计划。最终，培训计划的影响将根据以下长期记录来判断 完成培训计划的受训者，我们将随着时间的推移进行监控。