Southern HIV and Alcohol Research Consortium Administrative and Research Support Core

摘要 目前尚不清楚冠状病毒(新冠肺炎)大流行是对艾滋病毒结果产生了不同的影响，还是 农村或少数民族人群的饮酒行为。了解新冠肺炎如何改变艾滋病护理 饮酒可以加强未来艾滋病毒和酒精护理的提供，以提高这些疾病的复原力 程序。获取健康研究的机会也受到新冠肺炎的不利影响。这种向远程医疗的转变已经 有潜力帮助临床医生和研究人员与难以接触的人群建立联系。然而，我们需要 了解艾滋病毒携带者远程保健(PLWH)的可行性和可接受性 研究和改进未来酒精干预和艾滋病毒护理的提供。此请求是 对U24AA022002的补充，为南方艾滋病毒酒精研究提供支持性基础设施 财团(SHARC)，包括FL Cohort。FL队列的目标是更好地了解障碍 以及病毒抑制的促进者，重点是酒精使用。然而，计划中的FL队列将无法 以区分酒精使用或艾滋病毒护理的变化是否由于新冠肺炎，并不会有足够的人 来自农村或海地社区，以评估这些未得到充分服务的人口的不同影响。这 补充剂将有助于确定与COVID相关的社会隔离和COVID疾病如何影响 艾滋病毒护理连续体，酒精使用和治疗，以及对远程医疗的接受，表明对NOT-AA-20- 011和高度优先的艾滋病毒研究领域。本附录的目的是：1)确定 COVID疾病和心理社会因素的相关变化(例如，孤独、社会支持、经济 不安全、家庭暴力)对饮酒和艾滋病毒相关护理和健康结果的影响(遵守ART、护理 参与度和病毒抑制)在社交疏远措施之前和期间进行评估；2)延长FL 将招募到农村地区和海地社区的队列，并比较心理社会影响，变化 在农村与城市环境和海地社区中，在饮酒和与艾滋病毒相关的结果方面也是如此。3)考核 远程注册的可行性、可接受性和兴趣，以及为研究和交付收集数据 在患者和提供者中进行酒精干预和艾滋病毒临床护理，并比较最佳策略 跨社会人口群体(例如，年龄组、农村与城市、族裔群体)。我们将实现这些目标 目的是在母公司FL的现有措施中增加一份与COVID相关的调查问卷 队列研究、招募和来自农村地区和海地社区的额外150人 将完成这项研究的一个简单版本，并对PLWH进行定性访谈 和医疗保健人员更好地了解我们如何从危机中学习，以适应新的 干预措施。这项研究将通过直接告知与实施酒精有关的战略而产生影响 和艾滋病毒干预，通过扩大我们对新的传染病大流行的影响的知识 关于饮酒和艾滋病毒结果，并通过加强我们队列样本的总体代表性。

Abstract It is not clear whether the coronavirus (COVID-19) pandemic has differentially affected HIV outcomes or drinking behavior among rural or ethnic minority populations. Understanding how COVID-19 changes HIV care and alcohol use could strengthen future HIV and alcohol care delivery to increase the resilience of these programs. Access to health research is also adversely affected by COVID-19. This shift to telehealth has potential to help clinicians and researchers connect with hard-to-reach populations. However, we need to understand feasibility and acceptability of telehealth by persons living with HIV (PLWH) if we are to extend research and improve delivery of alcohol interventions and HIV care in the future. This request is supplementary to U24AA022002, providing supportive infrastructure to the Southern HIV Alcohol Research Consortium (SHARC), including the FL Cohort. The objective of the FL Cohort is to better understand barriers and facilitators to viral suppression, focusing on alcohol use. However, the planned FL Cohort will not be able to distinguish if changes in alcohol use or HIV care are due to COVID-19, and will not have sufficient persons from rural or Haitian communities to assess differential effects in these underserved populations. This supplement will help determine how COVID-related social isolation and COVID disease have influenced the HIV care continuum, alcohol use and treatment, and acceptance of telehealth, stated interests in NOT-AA-20- 011 and high priority HIV research areas. The aims of this supplement are to: 1) Determine the impacts of COVID disease and related changes in psychosocial factors (e.g., loneliness, social support, economic insecurity, domestic violence) on alcohol use and HIV-related care and health outcomes (ART adherence, care engagement, and viral suppression) as assessed before and during social distancing measures; 2) Extend FL Cohort recruitment into rural areas and the Haitian community, and compare the psychosocial effects, changes in drinking, and HIV-related outcomes in rural vs. urban settings and within the Haitian community. 3) Assess the feasibility, acceptability, and interest in remote enrollment and data collection for research, and delivery of alcohol interventions and HIV clinical care among patients and providers, and compare optimal strategies across socio-demographic groups (e.g., age cohort, rural vs. urban, ethnic groups). We will accomplish these aims by adding an additional COVID-related questionnaire to the existing measures in the parent FL Cohort study, recruiting and additional 150 persons from rural areas and the Haitian community who will complete a single, “light” version of the study, and conducting qualitative interviews from PLWH and healthcare personnel to better understand how we can learn from the crisis to adapt new interventions. The study will have impact by directly informing strategies related to implementation of alcohol and HIV interventions, by expanding our knowledge related to the impact of a new infectious disease pandemic on drinking and HIV outcomes, and by enhancing the overall representativeness of our cohort sample.