Translational Science Training to Reduce the Impact of Alcohol on HIV Infection

减少酒精对艾滋病毒感染影响的转化科学培训

• 批准号: 10700505
• 负责人: Robert L Cook
• 金额: $ 41.44万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-10 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10700505
• 关键词: Alcohols; HIV Infections; Training; Translational Research

This is an application to continue to support both predoctoral trainees and postdoctoral fellows in the T32 training program, “Translational Science Training to Reduce the Impact of Alcohol on HIV Infection”. This training need remains significant across the state of Florida which continues to rank among the top 3 states in new HIV infections per year and total HIV/AIDS cases. Alcohol consumption, and related issues such as drug use and mental health, contributes to enduring HIV transmission and to poor HIV outcomes. We need an interdisciplinary research task force skilled in alcohol research to help reduce HIV transmission and HIV- related comorbidities. The specific aims of our T32 are to: (1) Deliver an outstanding training curriculum focused on alcohol and HIV that incorporates three key focus areas (health behavior intervention science, epidemiology and data science, and cognitive science related to aging); (2) Provide effective mentorship for establishing or advancing programs of research in alcohol and HIV science; (3) Facilitate leaderships skills and experience collaborating with multidisciplinary research teams; (4) Promote excellence in the communication and dissemination of alcohol and HIV science; and (5) Ensure professionalism and ethical conduct of research. The training program will support five pre-doctoral and two post-doctoral trainees at any time and be based in 6 academic programs. The program is led by three MPIs who represent departments of Epidemiology, Health Education and Behavior, and Nursing. We will provide in-depth training around the intersection of alcohol and HIV, together with three additional focus areas: a) health behavior intervention science; b) epidemiology and data science integrated with the UF AI initiative; and c) cognitive science related to aging. Training activities include required courses, T32 Program activities, and training activities associated with the Southern HIV Alcohol Research Consortium (SHARC), itself supported by over $10 million in ongoing NIH funding through 2022. Trainees also will receive training in the responsible conduct of research. The research environment is strong at the University of Florida, which collectively has pledged an additional $500,000 in overall support to our specific training program. Given the success of our trainees to date, and breadth and depth of our faculty mentors’ expertise around alcohol and HIV, we reaffirm our readiness and commitment to training the next cohort of researchers to reduce the risk of negative health outcomes from alcohol and HIV infection throughout Florida and beyond.

这是一个应用程序，以继续支持在T32的博士前学员和博士后研究员 培训方案“减少酒精对艾滋病毒感染影响的转化科学培训”。这 佛罗里达州的培训需求仍然很大，该州继续在2009年的前三个州中排名第一。 艾滋病毒/艾滋病病例总数。酒精消费以及毒品等相关问题 吸毒和心理健康，助长了艾滋病毒的持久传播和艾滋病毒的不良后果。我们需要一个 跨学科研究工作队擅长酒精研究，以帮助减少艾滋病毒的传播和艾滋病毒- 相关合并症。我们的T32的具体目标是：（1）提供出色的培训课程 专注于酒精和艾滋病毒，包括三个关键领域（健康行为干预科学， 流行病学和数据科学，以及与衰老相关的认知科学）;（2）为以下人员提供有效的指导 建立或推进酒精和艾滋病科学研究计划;（3）促进领导技能， 与多学科研究团队合作的经验;（4）促进卓越的沟通 （5）确保研究的专业性和道德行为。 该培训计划将支持5名博士前和2名博士后学员在任何时候，并在6 学术课程。该计划由三名MPI领导，他们代表流行病学，卫生和健康部门， 教育和行为，和护理。我们将围绕酒精和酒精的交叉点提供深入的培训， 艾滋病毒，以及另外三个重点领域：a）健康行为干预科学; B）流行病学和 数据科学与UF AI倡议相结合; c）与衰老相关的认知科学。培训活动 包括必修课程、T32计划活动以及与南方艾滋病毒相关的培训活动 酒精研究联盟（SHARC），本身由超过1000万美元的持续NIH资金支持，通过 2022.受训人员还将接受负责任地开展研究的培训。研究环境是 在佛罗里达大学，他们共同承诺额外提供50万美元的总体支持， 我们的具体培训计划。鉴于我们的学员迄今为止的成功，以及我们教师的广度和深度， 导师在酒精和艾滋病毒方面的专业知识，我们重申我们准备并承诺培训下一个 一组研究人员，以减少酒精和艾滋病毒感染的负面健康结果的风险， 佛罗里达和更远的地方。

项目成果

A virtual reality platform for the measurement of drinking topography.

• DOI: 10.1016/j.drugalcdep.2021.109246
• 发表时间: 2022-02-01
• 期刊: DRUG AND ALCOHOL DEPENDENCE
• 影响因子: 4.2
• 作者: Schneider, Victor J., II;Bush, Nicholas;Vitus, Darya;Carpenter, Ryan W.;Robinson, Michael;Boissoneault, Jeff
• 通讯作者: Boissoneault, Jeff

Expectancy of alcohol analgesia moderates perception of pain relief following acute alcohol intake.

酒精镇痛的预期会缓和急性饮酒后疼痛缓解的感觉。

• DOI: 10.1037/pha0000664
• 发表时间: 2024
• 期刊: Experimental and clinical psychopharmacology
• 影响因子: 2.3
• 作者: Alexander,Casey;Bush,NicholasJ;Neubert,JohnK;Robinson,Michael;Boissoneault,Jeff
• 通讯作者: Boissoneault,Jeff

Repercussions of Rejecting Unwanted Advances: Gender Differences in Experience and Concern.

拒绝不需要的进展的后果：经验和关注方面的性别差异。

• DOI: 10.1080/19317611.2023.2175098
• 发表时间: 2023
• 期刊: International journal of sexual health : official journal of the World Association for Sexual Health
• 作者: Moran,James;Burch,Rebecca
• 通讯作者: Burch,Rebecca

Stress Mediates the Association Between Pain and Alcohol Use in College Students.

• DOI: 10.2147/jpr.s351837
• 发表时间: 2022
• 期刊: Journal of pain research
• 影响因子: 2.7
• 作者: Bush NJ;Schick MR;Spillane NS;Boissoneault J
• 通讯作者: Boissoneault J

Reasons for Marijuana Use and Its Perceived Effectiveness in Therapeutic and Recreational Marijuana Users Among People Living with HIV in Florida.

• DOI: 10.26828/cannabis/2021.01.002
• 发表时间: 2021
• 期刊: Cannabis (Albuquerque, N.M.)
• 作者: Sajdeya, Ruba;Joseph, Verlin;Stetten, Nichole E;Ibanez, Gladys E;Wang, Yan;Powell, Lauren;Somboonwit, Charurut;Corsi, Karen F;Cook, Robert L
• 通讯作者: Cook, Robert L