Impact of Social Cohesion and Social Capital in PrEP Uptake and Adherence Among Transwomen of Color
社会凝聚力和社会资本对跨性别有色人种女性 PrEP 的采用和坚持的影响
基本信息
- 批准号:10397977
- 负责人:
- 金额:$ 50.71万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-11 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAIDS/HIV problemAddressAdherenceAreaBehaviorBiologicalBirthCensusesClinicCodeCohort StudiesColorCommunitiesDancingDataData SetDevicesEligibility DeterminationEnvironmentEpidemicEthnic OriginExposure toFemaleFeminineFundingGender IdentityGeneral PopulationGeographic LocationsGeographyGlobal Positioning SystemGoalsHIVHIV InfectionsHIV SeronegativityIncidenceIndividualInterventionLinkLiteratureLocationLongitudinal StudiesMeasuresMethodologyMethodsNeighborhoodsNetwork-basedNew York CityOdds RatioOutcomeParticipantPathway AnalysisPatient Self-ReportPatternPersonsPhysical activityPoliciesPolygamyPopulationPrevalencePreventionProtocols documentationRaceReduce health disparitiesResearchResearch Project GrantsResourcesRiskSamplingScientific Advances and AccomplishmentsSexual and Gender MinoritiesSocial EnvironmentSocial NetworkSubgroupTechnologyTimeTravelUnited StatesUnited States National Institutes of HealthWomanWorkbasecohortcondomless anal sexcontextual factorsepidemiology studyexperiencefeasibility researchfollow-upgender minority grouphealth disparityimprovedinfection rateinnovationmalemen who have sex with menmetropolitanmultidisciplinarynext generationnovel strategiespre-exposure prophylaxispreventive interventionracial disparityrecruitsexskillssocialsocial capitalsocial cohesionsocial epidemiologysuccesssurveillance studytherapy developmenttransgendertransgender womentransmission processuptakeurban areawillingnesswomen of color
项目摘要
PROJECT SUMMARY
This project seeks to use real-time geospatial methods to investigate relationships between social cohesion
and social capital within Global Positioning System (GPS)-defined activity space neighborhoods and social
networks in relation to HIV pre-exposure prophylaxis (PrEP) uptake and adherence cross-sectionally and
longitudinally among transgender women (TW) of color (TWOC) in the New York City metropolitan statistical
area (MSA) followed over two years. We will recruit 250 TWOC in the proposed The N2 Study: Transgender
Women's Neighborhood and Networks Cohort Study to address the aims of the research. Eligibility
requirements include: identifying as a transgender woman (individuals who were assigned a male sex at birth
who identify as women, female, trans women, trans female, male-to-female or another diverse trans feminine
gender identity on the spectrum) of color; HIV-seronegative; being 18 to 55 years old; residing in the New York
City MSA; self-report no plans to move outside of the New York City metropolitan area in the next two years;
self-reporting no restrictions to usual physical activity; and self-report willingness to carry a small GPS device
for two-weeks at five points over the course of two years. Participants will wear the GPS device following
protocols used in our previous feasibility research projects, including studies among TW. In this longitudinal
study, six months after completing the initial 2-week GPS protocol, participants will carry the GPS device for an
additional 2-weeks every six-months over the two-year study period—for a total of five times. Multiple GPS
measures and multiple measures of social networks (at different time points) can better capture the breadth of
people's exposure to neighborhood-level factors and dynamics in social networks. Also, GPS activity space
environment and social networks data at baseline could potentially influence PrEP outcomes over time,
providing a clear temporal ordering and an ability to consider potential time-lags. The proposed study will be
the largest GPS study of HIV disparities in any transgender population and presents a remarkable opportunity
to study environmental influences on HIV. Findings from the proposed research will impact HIV prevention
intervention activities. First, the project will inform specific neighborhood-level policy interventions. For
example, increased community efforts through increased social cohesion in neighborhoods may be an HIV
prevention intervention that can reduce HIV health disparities. Second, from the GPS dataset we will know the
travel patterns of TW and therefore be able to identify optimal geographic locations for HIV prevention
interventions. This will advance the literature given that such interventions are seldom geographically targeted.
Third, examining changes in spatial mobility (i.e. activity spaces) over time will be useful in knowing whether
the risks of particular spaces change or remain constant because different neighborhoods will have different
risk profiles. Finally, our dynamic network analysis we propose will deepen understanding of the effects of
social networks on HIV prevention behaviors and will improve network-based HIV prevention interventions.
项目摘要
该项目旨在使用实时地理空间方法来调查社会凝聚力之间的关系,
全球定位系统(GPS)定义的活动空间社区和社会资本
与艾滋病毒暴露前预防(PrEP)的吸收和跨部门坚持有关的网络,
在纽约市大都市统计数据中,
MSA(MSA)是一个为期两年的项目。我们将在拟议的N2研究中招募250名TWOC:变性人
妇女的邻里和网络队列研究,以解决研究的目的。资格
要求包括:确定为变性妇女(出生时被指定为男性的个人)
认同为女性、女性、跨性别女性、跨性别女性、男性对女性或其他不同的跨性别女性的人
有色人种; HIV血清反应阴性;年龄在18 - 55岁之间;居住在纽约
城市MSA;自我报告没有计划在未来两年内搬离纽约市大都市区;
自我报告对日常体力活动没有限制;自我报告愿意携带小型GPS设备
在两年的时间里,在五个点上持续两周。参加者将佩戴GPS设备,
我们以前的可行性研究项目中使用的协议,包括TW之间的研究。在这一纵向
在完成最初的2周GPS方案后6个月,参与者将携带GPS设备进行为期6周的研究。
在两年的研究期间,每六个月增加两周,总共五次。多个GPS
社交网络的度量和多个度量(在不同时间点)可以更好地捕捉
人们在社交网络中接触到的邻里层面的因素和动态。此外,GPS活动空间
基线的环境和社交网络数据可能会随着时间的推移影响PrEP结果,
提供了清晰的时间排序和考虑潜在时滞的能力。拟议的研究将
全球定位系统对任何变性人群中艾滋病毒差异的最大研究,
研究环境对艾滋病的影响。拟议研究的结果将影响艾滋病毒预防
干预活动。首先,该项目将为具体的社区一级政策干预提供信息。为
例如,通过增加社区的社会凝聚力来增加社区的努力可能是一种艾滋病毒,
预防干预可以减少艾滋病毒健康差距。其次,从GPS数据集,我们将知道
TW的旅行模式,因此能够确定预防艾滋病毒的最佳地理位置
干预措施。这将推动文献,因为这种干预措施很少有地域针对性。
第三,研究空间流动性(即活动空间)随时间的变化将有助于了解
特定空间的风险变化或保持不变,因为不同的社区将有不同的
风险概况。最后,我们提出的动态网络分析将加深对
社交网络的艾滋病毒预防行为,并将改善基于网络的艾滋病毒预防干预措施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dustin T Duncan其他文献
Dustin T Duncan的其他文献
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{{ truncateString('Dustin T Duncan', 18)}}的其他基金
MyPEEPS Mobile LITE: Limited Interaction Efficacy Trial of MyPEEPS Mobile to Reduce HIV Incidence and Better Understand the Epidemiology of HIV among YMSM
MyPEEPS Mobile LITE:MyPEEPS Mobile 的有限交互功效试验可降低 YMSM 中的 HIV 发病率并更好地了解 HIV 流行病学
- 批准号:
10462265 - 财政年份:2022
- 资助金额:
$ 50.71万 - 项目类别:
MyPEEPS Mobile LITE: Limited Interaction Efficacy Trial of MyPEEPS Mobile to Reduce HIV Incidence and Better Understand the Epidemiology of HIV among YMSM
MyPEEPS Mobile LITE:MyPEEPS Mobile 的有限交互功效试验可降低 YMSM 中的 HIV 发病率并更好地了解 HIV 流行病学
- 批准号:
10676911 - 财政年份:2022
- 资助金额:
$ 50.71万 - 项目类别:
Characterizing Sleep, ART Adherence and Viral Suppression Among Black Sexual Minority Men
黑人性少数男性的睡眠、抗逆转录病毒治疗依从性和病毒抑制特征
- 批准号:
10682533 - 财政年份:2021
- 资助金额:
$ 50.71万 - 项目类别:
Characterizing Sleep, ART Adherence and Viral Suppression Among Black Sexual Minority Men
黑人性少数男性的睡眠、抗逆转录病毒治疗依从性和病毒抑制特征
- 批准号:
10327830 - 财政年份:2021
- 资助金额:
$ 50.71万 - 项目类别:
Cannabis use, PrEP and HIV transmission risk Among Black MSM in Chicago
芝加哥黑人男男性接触者中的大麻使用、PrEP 和艾滋病毒传播风险
- 批准号:
10300750 - 财政年份:2021
- 资助金额:
$ 50.71万 - 项目类别:
Cannabis use, PrEP and HIV transmission risk Among Black MSM in Chicago
芝加哥黑人男男性接触者中的大麻使用、PrEP 和艾滋病毒传播风险
- 批准号:
10456227 - 财政年份:2021
- 资助金额:
$ 50.71万 - 项目类别:
Cannabis use, PrEP and HIV transmission risk Among Black MSM in Chicago
芝加哥黑人男男性接触者中的大麻使用、PrEP 和艾滋病毒传播风险
- 批准号:
10674924 - 财政年份:2021
- 资助金额:
$ 50.71万 - 项目类别:
MINORITY HIV/AIDS RESEARCH INITIATIVE (MARI) TO BUILD HIV PREVENTION, TREATMENT AND RESEARCH CAPACITY IN
少数群体艾滋病毒/艾滋病研究计划 (MARI),旨在建立艾滋病毒预防、治疗和研究能力
- 批准号:
10115866 - 财政年份:2019
- 资助金额:
$ 50.71万 - 项目类别:
Impact of Social Cohesion and Social Capital in PrEP Uptake and Adherence Among Transwomen of Color - SGM Administrative Supplement
社会凝聚力和社会资本对有色跨性别女性接受和坚持 PrEP 的影响 - SGM 行政补充
- 批准号:
9931740 - 财政年份:2018
- 资助金额:
$ 50.71万 - 项目类别:
Impact of Social Cohesion and Social Capital in PrEP Uptake and Adherence Among Transwomen of Color
社会凝聚力和社会资本对跨性别有色人种女性 PrEP 的采用和坚持的影响
- 批准号:
9926730 - 财政年份:2018
- 资助金额:
$ 50.71万 - 项目类别: