NRSA Training Core
NRSA 培训核心
基本信息
- 批准号:10398854
- 负责人:
- 金额:$ 72.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-05-01 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:Active LearningBasic ScienceBioinformaticsBiologicalBiological SciencesBiologyBiomedical ResearchBostonChemicalsChemistryClinicalClinical MedicineClinical SciencesCommunitiesComplementDiagnosisDisciplineDiseaseDoctor of PhilosophyEducational CurriculumFacultyFoundationsFundingFutureGoalsHuman BiologyImmunologyInfrastructureLeadershipMentorsMethodologyMethodsNational Research Service AwardsNeurosciencesPatientsPhysiciansPreventionResearchScienceStudentsSystems BiologyTNFSF15 geneTimeTrainingTraining ProgramsTraining SupportTranslational ResearchTranslationsUniversitiesWorkforce Developmentbasecareercatalystexperiencegraduate studenthuman diseaselearning strategyprogramstranslational medicine
项目摘要
The Harvard Catalyst (HC) TL1 Training Program provides the organizational, curricular, and intellectual
infrastructure for creating and mentoring a community of students and faculty engaged in disease-oriented
research and the translation of principles of human biology to clinical medicine. TL1 offers an interdisciplinary
PhD program that integrates human biology and translational medicine training for graduate students in life
sciences graduate programs across Harvard University (HU). For the past nine years, the TL1 Program has
provided a cornerstone of support for some of the best graduate students in the Leder Human Biology Program
(LHB Program). TL1 currently supports 39 students, integrated in the larger community of 78 students in the
LHB program. Students in the TL1 program come from graduate programs across Harvard University,
including Biological and Biomedical Sciences, Neurosciences, Immunology, Systems Biology, and Chemistry
and Chemical Biology. The two TL1 Co-Leads, Connie Cepko, PhD, and Thomas Michel, MD, PhD, have
extensive and complementary expertise in basic, translational, and clinical science, and longstanding
experience in the leadership of graduate training programs.
Going forward, TL1 will continue to represent a key component of the HC Translational Workforce
Development (see Core D. Translational Endeavors). TL1 will expand to incorporate new training programs in
team science, quantitative methods, and bioinformatics that complement current programs to prepare an
effective biomedical research workforce of the future. Each year TL1 will select seven new first-year graduate
students. The average time to obtaining the PhD degree for TL1 students is 5.7 years. Awardees will be
supported for the first two years of their PhD studies, after which support will come from their PhD mentors'
research program, or from institutional funds or foundations.
The objectives of the TL1 Training Core are to: (Aim 1) Provide a graduate curriculum with a focus on
quantitative team-based active learning methods that will train graduate students in the mechanisms and
methodologies of human biology and disease-oriented T0/T1 discovery, and provide them with direct clinical
contact with patients and physicians; (Aim 2) Establish a context for human disease-oriented translational
research in paracurricular activities across HC that connect clinical medicine with student research in human
biology and translational medicine; and (Aim 3) Nurture a diverse community of students and faculty with
shared goals of applying rigorous methodologies to the translation of basic discoveries to prevention,
diagnosis, and treatment of human disease, while also reaching out into the broader Boston community.
TL1 will select and support the training of the best graduate students committed to careers in human biology
and translational medicine, and who will benefit from and contribute to the discipline at HU and beyond.
哈佛催化剂(HC) TL1培训计划提供组织,课程和智力
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Thomas Michel其他文献
Thomas Michel的其他文献
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{{ truncateString('Thomas Michel', 18)}}的其他基金
Hydrogen peroxide in endothelial function and dysfunction
过氧化氢在内皮功能和功能障碍中的作用
- 批准号:
10320952 - 财政年份:2021
- 资助金额:
$ 72.4万 - 项目类别:
Dynamic tissue-specific modulation of redox stress using chemogenetics
利用化学遗传学对氧化还原应激进行动态组织特异性调节
- 批准号:
10393690 - 财政年份:2021
- 资助金额:
$ 72.4万 - 项目类别:
Hydrogen peroxide in endothelial function and dysfunction
过氧化氢在内皮功能和功能障碍中的作用
- 批准号:
10543765 - 财政年份:2021
- 资助金额:
$ 72.4万 - 项目类别:
Dynamic tissue-specific modulation of redox stress using chemogenetics
利用化学遗传学对氧化还原应激进行动态组织特异性调节
- 批准号:
10214064 - 财政年份:2021
- 资助金额:
$ 72.4万 - 项目类别:
Chemogenetic approaches to define the roles of redox dysfunction in the cardiomyopathy of aging
化学遗传学方法确定氧化还原功能障碍在衰老心肌病中的作用
- 批准号:
9922852 - 财政年份:2019
- 资助金额:
$ 72.4万 - 项目类别:
REDOX REGULATION OF eNOS SIGNALING PATHWAYS IN VASCULAR ENDOTHELIUM
血管内皮细胞 eNOS 信号通路的氧化还原调节
- 批准号:
8250446 - 财政年份:2011
- 资助金额:
$ 72.4万 - 项目类别:
ANIMAL MODELS OF REDOX METABOLISM AND ARTERIAL DYSFUNCTION
氧化还原代谢和动脉功能障碍的动物模型
- 批准号:
8250450 - 财政年份:2011
- 资助金额:
$ 72.4万 - 项目类别:
REDOX REGULATION OF eNOS SIGNALING PATHWAYS IN VASCULAR ENDOTHELIUM
血管内皮细胞 eNOS 信号通路的氧化还原调节
- 批准号:
7975784 - 财政年份:2010
- 资助金额:
$ 72.4万 - 项目类别:
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