Interdisciplinary malaria research training in Malawi

项目总结 疟疾仍然是马拉维健康和生命的最大威胁之一，最近的控制努力 只取得了一定的成功。对决定风险的因素以及如何更有效地设计的新见解 必须采取干预措施，以加强控制并最终消除该区域的疟疾。这份全球报告 传染病科研培训计划是在历史悠久、成果丰硕的基础上建立起来的 马拉维大学医学院高级教员与 数十年来一直在马拉维从事疟疾研究的国际调查小组。这个 制定了培训计划，以培训在马拉维发展独立研究团队所需的专家 能够设计、领导和分析本地和国际相关研究的结果，并创造 在马拉维的大学里，一个强大的和可持续的研究生课程。精心挑选和训练一名 分子流行病学家、一名病媒生物学家和两名生物统计学家将培养健康研究领域的领导者。 议程，重点是假说驱动的科学问题。我们还将在以下方面提供正式的短期培训 实验室轮换的具体研究方法和量身定做的机会，以提供继任规划 建立一个未来的博士生和支持他们的初级教职员工的渠道。通过 对培训团队成员的直接监督、指导和指导，这些学员将受益于 出色的教育，也得益于经验丰富的同事的亲身指导 以及最近毕业的现在马拉维的教职员工。这项跨学科培训计划是 旨在实现以下具体目标：(1)培养成功的分子流行病学研究人员， 媒介生物学和生物统计学，(2)在马拉维建立严格、独立的博士项目的核心教师， 以及(3)支持马拉维未来博士生和导师的继任规划。的具体领域 培训被确定为马拉维正在进行的和未来的卫生研究必不可少的，反映了 合作机构(马里兰大学、密歇根州立大学和密歇根大学 Witwater srand)，并与马拉维大学内正在出现的机会创造协同效应。克罗斯- 削减、创新、良好执行和专业分析的研究将解决疟疾的具体挑战 治疗、预防和减少传播。此外，所有学员在本课程中开发的技能集 拟议的努力将适用于广泛的传染病和非传染性疾病。

PROJECT SUMMARY Malaria continues to be one of the greatest threats to health and life in Malawi, and recent control efforts have yielded only moderate success. New insights into what determines risk and how to design more effective interventions are imperative to enhance control and ultimately eliminate malaria in the region. This Global Infectious Diseases Research Training Program is established on the basis of long-standing and productive collaborations between senior faculty members at the University of Malawi College of Medicine and a core team of international investigators who have been engaged in malaria research in Malawi for decades. The training program was crafted to train the experts required to develop independent research teams in Malawi capable of designing, leading and analyzing results of locally and internationally relevant studies, and to create a robust and sustainable graduate program in Malawian universities. Careful selection and training of a molecular epidemiologist, a vector biologist and two biostatisticians will prepare leaders in the health research agenda, focused on hypothesis-driven scientific questions. We will also provide formal short course training in specific research methods and tailor opportunities for laboratory rotations to provide succession planning to create a pipeline of future PhD candidates and the junior faculty members who support them. Through the direct supervision, guidance and mentorship of the training team members, these trainees will benefit from outstanding didactic educations and also from the hands-on mentoring provided by experienced colleagues and recent graduates who are now faculty members in Malawi. This interdisciplinary training program is designed achieve the following specific aims: (1) Train successful investigators in molecular epidemiology, vector biology and biostatistics, (2) Establish core faculty for a rigorous, independent PhD program in Malawi, and (3) Support succession planning for future PhD trainees and mentors within Malawi. The specific areas of training were identified as essential to on-going and future health research in Malawi, reflect strengths of the collaborating institutions (University of Maryland, Michigan State University and University of the Witwatersrand), and create synergies with emerging opportunities within the University of Malawi. Cross- cutting, innovative, well-executed and expertly analyzed studies will address specific challenges of malaria treatment, prevention, and transmission reduction. In addition, the skill sets developed by all the trainees in this proposed effort will be applicable to a wide range of infectious as well as non-communicable diseases.