Project 2 -- MIDUS Daily Diary Project

摘要-日常日记项目 MIDUS每日项目的目标是确定每日压力过程中的短期波动 对中年和成年后的长期健康和幸福产生影响。具体目标是：(1) 最多四次评估日常压力源和日常幸福感的多个方面的变化 跨越长达30年的三个历史时期；(2)调查唾液的昼夜节律是如何被打乱的 皮质醇提供了一种连接日常压力和健康的生理机制；以及(3)增加了基于平板电脑的移动设备 对MIDUS方案的日常经验进行评估，以加强对压力过程的日常测量 并捕捉对认知健康的独特评估。这些目标将通过开展额外的 MIDUS核心项目和每日更新项目的纵向数据收集浪潮。我们将继续使用 一项为期8天的关于日常压力源和幸福感的电话日记研究，结合对唾液的多项评估 (4次×4d)获取唾液皮质醇。此外，我们还将添加为期14天的平板电脑数据收集 在每日电话调查之后。MIDUS Daily项目将继续吸纳富人 在我们分析研究的其他MIDUS项目中，社会人口统计、个性和认知测量 它们如何与长达30年的每日压力过程的变化相关联。我们还将使用来自基因的数据 表情、生物标记物和神经科学项目，以检查日常压力过程的变化如何预测 基因表达谱和各种健康指标的变化(例如，变态负荷、炎症性 过程、神经内分泌调节、心血管风险)。

ABSTRACT – DAILY DIARY PROJECT The objective of the MIDUS Daily Project is to determine how short term fluctuations in daily stress processes impact longer-term health and well-being throughout midlife and later adulthood. Specific aims are to: (1) Assess changes in multiple aspects of daily stressors and daily well-being across up to four occasions spanning up to 30 years and three historic periods; (2) Investigate how disrupted diurnal rhythms of salivary cortisol provide a physiological mechanism linking daily stress and health; and (3) Add tablet-based mobile assessments of daily experiences to the MIDUS protocol to enhance daily measurements of stress processes and capture unique assessments of cognitive health. These aims will be addressed by conducting additional waves of longitudinal data collection for the MIDUS Core and Refresher Daily projects. We will continue to use an 8-day telephone diary study of daily stressors and well-being combined with multiple assessments of saliva (4 occasions × 4 days) to obtain salivary cortisol. In addition, we will add a 14-day tablet data collection following the daily telephone survey. The MIDUS Daily project will continue to incorporate the rich sociodemographic, personality, and cognitive measures from other MIDUS projects in our analyses to study how they relate to changes in daily stress processes over up to 30 years. We will also use data from the gene expression, biomarker, and neuroscience projects to examine how changes in daily stress processes predict gene expression profiles and changes in various indicators of health (e.g., allostatic load, inflammatory processes, neuroendocrine regulation, cardiovascular risk).