High Performance PET/CT Scanner

高性能 PET/CT 扫描仪

• 批准号: 10630534
• 负责人: Ciprian Catana
• 金额: $ 200万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10630534
• 关键词: Accounting; Award; Boston; Cardiovascular Diseases; Clinical Research; Collaborations; Communities; Complement; Data; Fostering; Funding; Future; Generations; Grant; Image; Institution; Leadership; Lung diseases; Magnetic Resonance Imaging; Maintenance; Measurement; Oncology; Organ; PET/CT scan; Performance; Positron-Emission Tomography; Price; Radiation exposure; Radiology Specialty; Research; Research Personnel; Research Project Grants; Schedule; System; Time; Tracer; United States National Institutes of Health; Vision; biomedical imaging; detector; improved; instrument; instrumentation; meter; multidisciplinary; operation; programs; radiotracer; temporal measurement

Project Summary/Abstract This application seeks support from the ORIP High-End Instrumentation Grant program to purchase a high-performance PET/CT scanner to be used for basic/translational/clinical research at the MGH/HST Athinoula A. Martinos Center for Biomedical Imaging. The proposed instrument – Siemens Biograph Vision Quadra – has a 1-meter long axial field of view and uses the latest generation PET detectors with excellent time-of-flight performance. The one order of magnitude higher sensitivity of the Biograph Vision Quadra PET/CT would benefit existing and future projects by allowing investigators to: obtain higher quality PET images, reduce radiation exposure and/or imaging acquisition time, image longer time after radiotracer administration, perform simultaneous multi-organ dynamic acquisition, improve the PET data quantification, perform multi-tracer studies, increase the temporal resolution of the PET measurements, etc. These new opportunities will benefit the ongoing research projects of our multidisciplinary NIH-funded investigators from MGH and Greater Boston region. Furthermore, the substantially better PET performance combined with the high-performance CT will complement the capabilities of the conventional PET/MRI and MRI scanners installed at the Martinos Center and will foster opportunities for new projects and collaborations for projects ranging from cardiovascular and pulmonary diseases to oncological and non-oncological whole-body applications. The proposed purchase through this SIG is being supported by the MGH leadership, Radiology Department, and Martinos Center. This multi-level institutional support covers every aspect related to the upgrade and its future operations, including allocation of instrument space and assistance for installation, operational support in terms of system scheduling, accounting, and maintenance, and lastly but most significantly, a commitment of up to $7,500,000 to cover the gap between the NIH SIG award and the purchasing price for the upgrade, in addition to the committed fund of $150,000 from the MGH Executive Committee for Research towards the maintenance of the system. Following the installation, the Biograph Vision Quadra PET/CT will be managed by the Martinos Center as a shared core, and made available to the broader research community, both within MGH and the Greater Boston region.

项目摘要/摘要 此应用程序寻求ORIP高端仪器设备资助计划的支持，以 购买用于基础/转换/临床研究的高性能PET/CT扫描仪 在MGH/HST阿蒂努拉·A·马蒂诺斯生物医学成像中心。拟议的文书 -西门子Biograph Vision Quadra-拥有1米长的轴向视场，并使用最新的 具有卓越飞行时间性能的新一代PET探测器。一个数量级 Bioggraph Vision Quadra PET/CT的更高灵敏度将使现有和未来的项目受益 通过允许调查人员：获得更高质量的PET图像，减少辐射暴露和/或 成像采集时间，放射性示踪剂注射后图像时间较长，同时进行 多器官动态采集，提高PET数据量化，进行多示踪 研究，提高PET测量的时间分辨率等。这些新的机会 将使我们由NIH资助的多学科研究人员的正在进行的研究项目受益于 MGH和大波士顿地区。此外，实质上更好的PET性能 与高性能CT相结合将补充传统CT的能力 在马蒂诺斯中心安装了PET/MRI和MRI扫描仪，将为新的 项目和协作的范围从心血管和肺部疾病到 肿瘤学和非肿瘤学全身应用。建议通过此购买 SIG得到了MGH领导层、放射科和马蒂诺斯中心的支持。这 多层次的制度支持涵盖了与升级及其未来相关的方方面面 作业，包括分配仪器空间和协助安装，作业 在系统调度、记账和维护方面提供支持，最后但也是大多数 值得注意的是，高达7,500,000美元的承诺用于弥补NIH SIG奖金和 升级的购买价，以及MGH承诺的150,000美元 系统维护研究执行委员会。紧随其后的是 安装后，Bioggraph Vision Quadra PET/CT将由Martinos中心作为 共享核心，并向更广泛的研究社区提供，包括在MGH和 大波士顿地区。