High Performance PET/CT Scanner

高性能 PET/CT 扫描仪

• 批准号: 10630534
• 负责人: Ciprian Catana
• 金额: $ 200万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10630534
• 关键词: Accounting; Award; Boston; Cardiovascular Diseases; Clinical Research; Collaborations; Communities; Complement; Data; Fostering; Funding; Future; Generations; Grant; Image; Institution; Leadership; Lung diseases; Magnetic Resonance Imaging; Maintenance; Measurement; Oncology; Organ; PET/CT scan; Performance; Positron-Emission Tomography; Price; Radiation exposure; Radiology Specialty; Research; Research Personnel; Research Project Grants; Schedule; System; Time; Tracer; United States National Institutes of Health; Vision; biomedical imaging; detector; improved; instrument; instrumentation; meter; multidisciplinary; operation; programs; radiotracer; temporal measurement

Project Summary/Abstract This application seeks support from the ORIP High-End Instrumentation Grant program to purchase a high-performance PET/CT scanner to be used for basic/translational/clinical research at the MGH/HST Athinoula A. Martinos Center for Biomedical Imaging. The proposed instrument – Siemens Biograph Vision Quadra – has a 1-meter long axial field of view and uses the latest generation PET detectors with excellent time-of-flight performance. The one order of magnitude higher sensitivity of the Biograph Vision Quadra PET/CT would benefit existing and future projects by allowing investigators to: obtain higher quality PET images, reduce radiation exposure and/or imaging acquisition time, image longer time after radiotracer administration, perform simultaneous multi-organ dynamic acquisition, improve the PET data quantification, perform multi-tracer studies, increase the temporal resolution of the PET measurements, etc. These new opportunities will benefit the ongoing research projects of our multidisciplinary NIH-funded investigators from MGH and Greater Boston region. Furthermore, the substantially better PET performance combined with the high-performance CT will complement the capabilities of the conventional PET/MRI and MRI scanners installed at the Martinos Center and will foster opportunities for new projects and collaborations for projects ranging from cardiovascular and pulmonary diseases to oncological and non-oncological whole-body applications. The proposed purchase through this SIG is being supported by the MGH leadership, Radiology Department, and Martinos Center. This multi-level institutional support covers every aspect related to the upgrade and its future operations, including allocation of instrument space and assistance for installation, operational support in terms of system scheduling, accounting, and maintenance, and lastly but most significantly, a commitment of up to $7,500,000 to cover the gap between the NIH SIG award and the purchasing price for the upgrade, in addition to the committed fund of $150,000 from the MGH Executive Committee for Research towards the maintenance of the system. Following the installation, the Biograph Vision Quadra PET/CT will be managed by the Martinos Center as a shared core, and made available to the broader research community, both within MGH and the Greater Boston region.

项目摘要/摘要 本申请向Orip高端仪器赠款计划寻求支持 购买用于基本/转化/临床研究的高性能宠物/CT扫描仪 在MGH/HST Athinoula A. Martinos生物医学成像中心。提议的仪器 - 西门子的传记视觉Quadra - 具有1米长的轴向视野，并使用了最新的视野 具有出色飞行时间性能的生成宠物探测器。一个数量级 Quadra PET/CT的更高敏感性将使现有项目和未来项目受益 通过允许研究人员：获得更高质量的PET图像，减少辐射暴露和/或 成像采集时间，放射性示意剂后更长的图像同时执行 多器官动态采集，提高PET数据数量，执行多跟踪器 研究，增加宠物测量的临时分辨率等。这些新机会 将受益于我们多学科NIH资助的研究人员正在进行的研究项目 MGH和大波士顿地区。此外，宠物性能更好 结合高性能CT将完成常规的功能 宠物/MRI和MRI扫描仪安装在马提尼斯中心，将为新的机会提供新的机会 从心血管和肺部疾病到项目的项目和合作 肿瘤学和非综合全身应用。提议的购买 SIG得到了MGH领导力，放射科和马提尼斯中心的支持。这 多层次的机构支持涵盖了与升级及其未来有关的各个方面 操作，包括仪器空间的分配和安装协助，运营 在系统调度，会计和维护方面的支持，最后，但大多数 值得注意的是，最高$ 7,500,000的承诺涵盖了NIH SIG奖和 升级的购买价格除了从MGH的150,000美元的承诺基金外 执行委员会维护系统的研究委员会。跟随 安装，Martinos Center将作为一个 共享核心，并在MGH和MGH内部提供了更广泛的研究社区 大波士顿地区。