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Activation Transcription Factor-4: Novel Regulator of Smooth Muscle Cell Repair and Intimal Thickening through Tenascin C

Activation Transcription Factor-4: Novel Regulator of Smooth Muscle Cell Repair and Intimal Thickening through Tenascin C
激活转录因子 4：通过腱蛋白 C 调节平滑肌细胞修复和内膜增厚
批准号：
nhmrc : 1030767
负责人：
Prof Levon Khachigian
金额：
$15.22万
依托单位：
The University of New South Wales
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2012
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2012-01-01 至 2013-12-31
来源：
https://researchdata.edu.au/activation-transcription-factor-tenascin-c/110773
关键词：
ActivationTranscriptionFactorNovelRegulator

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中文摘要
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英文摘要
CVD represents the most important cause of morbidity and mortality in the world, accounting for 35% of all deaths in Australia. Smooth muscle cell growth accounts for a range of vascular proliferative disorders. This project focuses on understanding the role of ATF-4 as a new key regulator of SMC proliferation and intimal thickening in injured vessels. Moreover, strategies targeting ATF-4 will facilitate future therapeutic strategies to control intimal thickening in patients with vascular disease.
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会议论文
Growth Regulatory Transcriptional Networks and Novel Therapies in Vascular Pathobiology
  • 批准号：
    nhmrc : 1059123
  • 项目类别：
    Research Fellowships
  • 资助金额：
    $18.28万
  • 财政年份：
    2020
  • 负责人：
    Prof Levon Khachigian
  • 依托单位：
Growth Regulatory Transcriptional Networks and Novel Therapies in Vascular Pathobiology
  • 批准号：
    nhmrc : GNT1059123
  • 项目类别：
    Research Fellowships
  • 资助金额：
    $85.2万
  • 财政年份：
    2016
  • 负责人：
    Prof Levon Khachigian
  • 依托单位：
Novel Small Molecule FosB/AP-1 Inhibitors for the Prevention of Proliferative Vascular Disorders
  • 批准号：
    nhmrc : 1030769
  • 项目类别：
    NHMRC Project Grants
  • 资助金额：
    $22.91万
  • 财政年份：
    2012
  • 负责人：
    Prof Levon Khachigian
  • 依托单位：
    The University of New South Wales
Novel mechanisms of early growth response-1 activation through the epidermal growth factor receptor
  • 批准号：
    DP120101557
  • 项目类别：
    Discovery Projects
  • 资助金额：
    $20.45万
  • 财政年份：
    2012
  • 负责人：
    Prof Levon Khachigian
  • 依托单位：
    The University of New South Wales
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