Emory Clinical Oncology Career Development Award K12 Program

埃默里临床肿瘤学职业发展奖 K12 计划

• 批准号: 10680377
• 负责人: Kavita Madhav Dhodapkar
• 金额: $ 55.37万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-02 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10680377
• 关键词: Address; Area; Clinical; Clinical Oncology; Clinical Research; Development; Diverse Workforce; Evaluation; Faculty; Funding; Future; Goals; Growth; Infrastructure; International; K-Series Research Career Programs; Knowledge; Lead; Malignant Neoplasms; Master of Science; Measures; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Methods; Modification; Phase I Clinical Trials; Phase II Clinical Trials; Program Evaluation; Records; Research; Research Methodology; Research Personnel; Research Training; Therapeutic; Training; Training Programs; Translational Research; Underrepresented Minority; Universities; Woman; anticancer research; career development; design; early phase clinical trial; experience; instructor; member; next generation; professor; programs; recruit; research study; skills; tool

Project Summary/Abstract To address the need for a well-trained, diverse workforce of cancer investigators, we will establish a K12- funded oncology clinical research training and mentorship program for junior faculty researchers at Emory University's Winship Cancer Institute. The goals of the Emory Clinical Oncology Career Development Award Program are to: (1) establish an exceptional training program for clinician-investigators in the conduct of therapeutic cancer clinical research studies with a focus on phase 1 and phase 2 clinical trials, and (2) develop the next generation of researchers and leaders in clinical oncology. In year 1, we will develop the program recruitment materials; convene the program Internal and External Advisory Boards including faculty with expertise in clinical/translational research, clinical research methodology, and mentorship; finalize the intensive training, longitudinal training, career development, and mentored research experience program components; select the inaugural Emory Clinical Oncology Career Development Award Scholars; and implement the online program evaluation and Scholar evaluation tools. Two clinician-investigator junior faculty members (Instructor or Assistant Professor) will be selected each year and Scholars will complete a 2-year training program. To develop the knowledge and skills necessary to become independent cancer clinician-investigators and lead cancer research teams in the future, in years 2-5 Emory Clinical Oncology K12 Scholars will pursue: intensive didactic training focused on clinical research methodology for design and execution of early phase clinical trials; longitudinal didactic coursework leading to a Master of Science in Clinical Research (MSCR) degree; mentored research experiences, and professional development activities. The Emory Clinical Oncology K12 program will leverage the strengths and infrastructure of the Georgia Clinical & Translational Science Alliance at Emory. A comprehensive, rigorous mixed-methods evaluation plan will be used to assess program milestones and metrics, identify areas for modifications and growth, and measure the long-term impact of the Emory Clinical Oncology K12 program. Recruitment of women and under-represented minority candidates will be an important focus of this K12. The two PIs are internationally recognized cancer researchers with exceptional track records as mentors.

项目摘要/摘要 为了满足对训练有素、多元化的癌症研究人员的需求，我们将建立一支K12- 埃默里大学为初级教职研究人员资助的肿瘤学临床研究培训和导师计划 大学的温希普癌症研究所。埃默里临床肿瘤学职业发展奖的目标 方案是：(1)为临床医生和研究人员建立一个特殊的培训方案 治疗性癌症临床研究，重点是第一阶段和第二阶段临床试验，以及(2)发展 临床肿瘤学的下一代研究人员和领导者。在第一年，我们将开发该项目 招聘材料；召集该计划的内部和外部咨询委员会，包括具有 在临床/转化性研究、临床研究方法论和导师指导方面的专业知识；完成密集的 培训、纵向培训、职业发展和指导研究经验计划的组成部分； 评选首届埃默里临床肿瘤学职业发展奖奖学金获得者；并实施在线 项目评估和学者评估工具。两名临床医生兼调查员初级教员(讲师 或助理教授)将每年被挑选出来，学者将完成一个为期两年的培训计划。至 培养成为独立癌症临床医生所需的知识和技能--调查人员和领导 未来癌症研究团队，在2-5年埃默里临床肿瘤学K12学者将追求：密集 讲授培训侧重于设计和实施早期临床的临床研究方法 试验；纵向教学课程，获得临床研究(MSCR)理学硕士学位； 有指导的研究经验和专业发展活动。埃默里临床肿瘤学K12 该计划将利用佐治亚州临床与转化科学联盟的优势和基础设施 在埃默里。将使用全面、严格的混合方法评估计划来评估计划 里程碑和指标，确定需要修改和增长的领域，并衡量 埃默里临床肿瘤学K12计划。征聘妇女和任职人数不足的少数族裔候选人将 成为这个K12的一个重要焦点。这两位PI是国际公认的癌症研究人员， 作为导师，他有着出色的记录。

项目成果

Association of Brachytherapy Boost with Overall Survival for Gleason 9-10 Prostate Cancer: The Impact of Primary versus Secondary Pattern 5.

近距离放射治疗增强与格里森 9-10 前列腺癌总体生存率的关联：主要模式与次要模式的影响 5。

• DOI: 10.1016/j.brachy.2022.12.004
• 发表时间: 2023
• 期刊: Brachytherapy
• 影响因子: 1.9
• 作者: Patel,SagarA;Baumann,Brian;Michalski,Jeff;Brenneman,Randall;Zheng,Bill;Gay,Hiram;Ferraro,Daniel;Brown,SimonA;Chang,AlbertJ;Rossi,PeterJ;Fischer-Valuck,BenjaminW
• 通讯作者: Fischer-Valuck,BenjaminW

A systematic review of diagnostic, prognostic, and risk blood and urine biomarkers of transplant-associated thrombotic microangiopathy.

• DOI: 10.3389/fimmu.2022.1064203
• 发表时间: 2022
• 期刊: Frontiers in immunology
• 影响因子: 7.3

External Beam Radiation Therapy With or Without Brachytherapy Boost in Men With Very-High-Risk Prostate Cancer: A Large Multicenter International Consortium Analysis.

外束放射治疗联合或不联合近距离放射治疗对患有极高风险前列腺癌的男性有效果：一项大型多中心国际联盟分析。

• DOI: 10.1016/j.ijrobp.2022.09.075
• 发表时间: 2023
• 期刊: International journal of radiation oncology, biology, physics
• 作者: Patel,SagarA;Ma,TingMartin;Wong,JessicaK;Stish,BradleyJ;Dess,RobertT;Pilar,Avinash;Reddy,Chandana;Wedde,TrudeB;Lilleby,WolfgangA;Fiano,Ryan;Merrick,GregoryS;Stock,RichardG;Demanes,DJeffrey;Moran,BrianJ;Tran,PhuocT