Emory Clinical Oncology Career Development Award K12 Program

埃默里临床肿瘤学职业发展奖 K12 计划

• 批准号: 10680377
• 负责人: Kavita Madhav Dhodapkar
• 金额: $ 55.37万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-02 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10680377
• 关键词: Address; Area; Clinical; Clinical Oncology; Clinical Research; Development; Diverse Workforce; Evaluation; Faculty; Funding; Future; Goals; Growth; Infrastructure; International; K-Series Research Career Programs; Knowledge; Lead; Malignant Neoplasms; Master of Science; Measures; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Methods; Modification; Phase I Clinical Trials; Phase II Clinical Trials; Program Evaluation; Records; Research; Research Methodology; Research Personnel; Research Training; Therapeutic; Training; Training Programs; Translational Research; Underrepresented Minority; Universities; Woman; anticancer research; career development; design; early phase clinical trial; experience; instructor; member; next generation; professor; programs; recruit; research study; skills; tool

Project Summary/Abstract To address the need for a well-trained, diverse workforce of cancer investigators, we will establish a K12- funded oncology clinical research training and mentorship program for junior faculty researchers at Emory University's Winship Cancer Institute. The goals of the Emory Clinical Oncology Career Development Award Program are to: (1) establish an exceptional training program for clinician-investigators in the conduct of therapeutic cancer clinical research studies with a focus on phase 1 and phase 2 clinical trials, and (2) develop the next generation of researchers and leaders in clinical oncology. In year 1, we will develop the program recruitment materials; convene the program Internal and External Advisory Boards including faculty with expertise in clinical/translational research, clinical research methodology, and mentorship; finalize the intensive training, longitudinal training, career development, and mentored research experience program components; select the inaugural Emory Clinical Oncology Career Development Award Scholars; and implement the online program evaluation and Scholar evaluation tools. Two clinician-investigator junior faculty members (Instructor or Assistant Professor) will be selected each year and Scholars will complete a 2-year training program. To develop the knowledge and skills necessary to become independent cancer clinician-investigators and lead cancer research teams in the future, in years 2-5 Emory Clinical Oncology K12 Scholars will pursue: intensive didactic training focused on clinical research methodology for design and execution of early phase clinical trials; longitudinal didactic coursework leading to a Master of Science in Clinical Research (MSCR) degree; mentored research experiences, and professional development activities. The Emory Clinical Oncology K12 program will leverage the strengths and infrastructure of the Georgia Clinical & Translational Science Alliance at Emory. A comprehensive, rigorous mixed-methods evaluation plan will be used to assess program milestones and metrics, identify areas for modifications and growth, and measure the long-term impact of the Emory Clinical Oncology K12 program. Recruitment of women and under-represented minority candidates will be an important focus of this K12. The two PIs are internationally recognized cancer researchers with exceptional track records as mentors.

项目摘要/摘要 为了满足癌症研究人员训练有素，多样化的劳动力的需求，我们将建立K12-- 为埃默里（Emory）的初级教师研究人员提供资助的肿瘤学临床研究培训和指导计划 大学的Winship癌症研究所。 Emory临床肿瘤学职业发展奖的目标 计划是：（1）为临床医生评估者建立卓越的培训计划 治疗性癌症临床研究研究重点是第1阶段和第2阶段临床试验，（2）发展 临床肿瘤学领域的下一代研究人员和领导者。在第一年，我们将开发该计划 招聘材料；召集该计划的内部和外部咨询委员会，包括教师 临床/转化研究，临床研究方法和指导方面的专业知识；最终确定密集型 培训，纵向培训，职业发展以及指导的研究经验计划组件； 选择首届Emory临床肿瘤学职业发展奖学者；并实施在线 计划评估和学者评估工具。两名临床医生评论者初级教师（讲师 或助理教授）每年都会选择，学者将完成2年的培训计划。到 发展成为独立癌症临床医生评估者所需的知识和技能，并领导 未来的癌症研究团队，在2 - 5年内，Emory临床肿瘤学K12学者将追求：密集型 教学培训的重点是设计和执行早期临床的临床研究方法 试验；纵向教学课程导致临床研究硕士学位（MSCR）学位； 指导的研究经验和专业发展活动。 Emory临床肿瘤学K12 计划将利用佐治亚州临床与转化科学联盟的优势和基础设施 在埃默里。全面，严格的混合方法评估计划将用于评估计划 里程碑和指标，确定修改和增长的领域，并衡量 Emory临床肿瘤学K12计划。招募妇女和代表不足的少数民族候选人将 成为此K12的重要重点。这两个PI是国际公认的癌症研究人员 作为导师的出色记录。

项目成果

Association of Brachytherapy Boost with Overall Survival for Gleason 9-10 Prostate Cancer: The Impact of Primary versus Secondary Pattern 5.

近距离放射治疗增强与格里森 9-10 前列腺癌总体生存率的关联：主要模式与次要模式的影响 5。

• DOI: 10.1016/j.brachy.2022.12.004
• 发表时间: 2023
• 期刊: Brachytherapy
• 影响因子: 1.9
• 作者: Patel,SagarA;Baumann,Brian;Michalski,Jeff;Brenneman,Randall;Zheng,Bill;Gay,Hiram;Ferraro,Daniel;Brown,SimonA;Chang,AlbertJ;Rossi,PeterJ;Fischer-Valuck,BenjaminW
• 通讯作者: Fischer-Valuck,BenjaminW

External Beam Radiation Therapy With or Without Brachytherapy Boost in Men With Very-High-Risk Prostate Cancer: A Large Multicenter International Consortium Analysis.

外束放射治疗联合或不联合近距离放射治疗对患有极高风险前列腺癌的男性有效果：一项大型多中心国际联盟分析。

• DOI: 10.1016/j.ijrobp.2022.09.075
• 发表时间: 2023
• 期刊: International journal of radiation oncology, biology, physics
• 作者: Patel,SagarA;Ma,TingMartin;Wong,JessicaK;Stish,BradleyJ;Dess,RobertT;Pilar,Avinash;Reddy,Chandana;Wedde,TrudeB;Lilleby,WolfgangA;Fiano,Ryan;Merrick,GregoryS;Stock,RichardG;Demanes,DJeffrey;Moran,BrianJ;Tran,PhuocT

A systematic review of diagnostic, prognostic, and risk blood and urine biomarkers of transplant-associated thrombotic microangiopathy.

• DOI: 10.3389/fimmu.2022.1064203
• 发表时间: 2022
• 期刊: Frontiers in immunology
• 影响因子: 7.3