2023 Silk Proteins and the Transition to Biotechnologies Gordon Research Conference

2023 年丝蛋白和向生物技术的过渡戈登研究会议

• 批准号: 10681751
• 负责人: DAVID L. KAPLAN
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10681751
• 关键词: Academia; Acceleration; Address; Antibiotics; Area; Biocompatible Materials; Biological Models; Biology; Biomedical Engineering; Biotechnology; Bombyx; Chemistry; Collaborations; Development; Devices; Emerging Technologies; Engineering; Environment; Enzymes; Exhibits; Fostering; Foundations; Friends; Funding; Future; Goals; Growth Factor; Harvest; Hour; Implant; Industry; Inflammation; Inflammatory Response; Intervention; Mechanics; Medical; Medical Device; Medical Technology; Medicine; Modeling; Molecular Weight; National Institute of Biomedical Imaging and Bioengineering; Pharmaceutical Preparations; Polymers; Process; Property; Protein Family; Proteins; Regenerative Medicine; Research; Running; Schedule; Science; Silk; Spiders; Structure; Students; System; Technology; Textiles; Therapeutic; Translations; Underrepresented Populations; Variant; Virginia; Water; Woman; amphiphilicity; aqueous; biodegradable polymer; biomaterial compatibility; commercialization; copolymer; design; implanted sensor; in vivo; insight; knowledge base; materials science; meetings; multidisciplinary; novel; physical science; recruit; self assembly; symposium; tissue reconstruction; tissue regeneration; translational impact; translational potential; vaccine delivery; wearable sensor technology

Project Summary The goal of this project is to support a Gordon Research Conference on silk materials. The objective of the conference is to cover research and technologies that are emerging utilizing silk-based biomaterials and to catalyze further translational efforts in the field. The plan is to bring together experts in the field of silk science from academia and industry from around the world to focus on current advances in the understanding and utilization of this unique family of proteins from silkworms and spiders, from both fundamental and applied perspectives, and to foster collaborations with the aim to give everyone an equal platform to showcase their science and technologies. Silk Biomaterials and Engineering Platform - Developing further fundamental and translational insight into silk protein self-assembly, bioengineering, chemistry, processing and new materials engineering provides the foundation for a wide range of advances in the field of protein-based biomaterials. These insights also impact broader needs in biomaterials science and engineering, utilizing silk as a unique model polymer due to its block copolymer structure, high molecular weight amphiphilic features, and aqueous processability. These insights should inform new ideas in biomaterials science and engineering, new silk protein-based products for medical needs, and new trainees excited and informed to join the field. Medical Interventions - Impact in the field of implantable, biocompatible and fully degradable medical devices is anticipated from the discussions at the GRC. We anticipate that the information gained at the meeting should facilitate new medical impact, from vaccine delivery to tissue reconstruction and implantable and wearable sensors. The conference emphasizes diversity and women with strong representation, while providing support for inclusion of under-represented groups with funding support for attendance. We also have scheduled a GRC power hour afternoon session, which will be run by women in STEM. Broader Impact - The use of silk in medically relevant areas is timely related to the push towards sustainable technologies and green chemistry, as silk is generated in an eco-friendly manner and harvested in water for use in textiles today. The transition toward medical needs with this novel protein-based material, along with broader implications in new environmentally related applications, offers to propel new silk technologies forward; utilizing water, exploiting degradability, and meeting energy and related requirements.

项目摘要 该项目的目标是支持戈登研究会议上的丝绸材料。的目的 会议将涵盖利用丝基生物材料的研究和技术， 促进该领域的进一步翻译工作。该计划将汇集丝绸科学领域的专家 来自世界各地的学术界和工业界的代表， 利用这个独特的蛋白质家族从蚕和蜘蛛，从基础和应用 观点，并促进合作，旨在为每个人提供一个平等的平台，以展示他们的 科学和技术。丝绸生物材料与工程平台-进一步发展基础和 对丝蛋白自组装、生物工程、化学、加工和新材料的翻译见解 工程学为基于蛋白质的生物材料领域的广泛进展提供了基础。 这些见解也影响了生物材料科学和工程的更广泛需求，利用丝作为一种独特的 模型聚合物由于其嵌段共聚物结构、高分子量两亲性特征和水溶性， 加工性能这些见解应该为生物材料科学和工程提供新的想法， 为满足医疗需求的蛋白质产品，新学员兴奋并了解了加入该领域的情况。医疗 干预措施----对植入式、生物相容性和完全可降解医疗器械领域的影响 这一点，是在GRC的讨论中提出来的。我们预计，会议上获得的信息应 促进新的医疗影响，从疫苗输送到组织重建，以及植入式和可穿戴式 传感器.会议强调多样性和具有强大代表性的女性，同时提供支持 为代表人数不足的群体提供参加会议的资金支持。我们还安排了一个 电力小时下午会议，这将是由妇女在干运行。 更广泛的影响-在医学相关领域使用丝绸与推动可持续发展及时相关 技术和绿色化学，因为丝绸是以生态友好的方式产生的，并在水中收获， 今天的纺织品。这种新型蛋白质基材料向医疗需求的转变，沿着 在新的环境相关应用中具有更广泛的意义，有助于推动新的丝绸技术 向前发展;利用水，开发降解性，并满足能源和相关要求。