ACCESS: Accelerating Cervical Cancer Elimination through the integration of Screen-and-treat Services

项目摘要 我的提案是对特别关注通知（NOSI）（编号为NOT-CA-23-038）的回应。 我是医学社会学和人类学的助理教授，也是研究中心的研究员。 翻译和实施科学（CTAIR）在尼日利亚大学，恩苏卡。我的研究主要集中在 姑息治疗（PC），癌症和低收入和中等收入国家（LMIC）的妇女健康。这 行政补充导师奖将为我提供所需的支持，以实现以下3个关键 在LMIC环境中进行研究的职业发展目标：（1）提高我在社区中的技能 参与式研究，利益相关者的参与和计划整合，特别是在PC临床环境中;（2） 深入了解实施框架和方法，以帮助缩小以下方面的差距 实施科学和实施实践;（3）获得PC研究的技能和内容专业知识。我 我将进行研究，并与我的导师至少40%的时间在尼日利亚 实施科学联盟-模式创新和研究中心（NISA-MIRC），一个基于实践的 在尼日利亚的六个地理区域的研究网络。为了实现这些目标，我 我们的导师团队包括：（1）美国小学导师，来自加州大学的Gregory Aarons教授， 圣地亚哥，他是实施科学方面的专家;（2）LMIC主要导师，Echeanolue教授 来自尼日利亚大学，他是社区参与性研究和临床研究方面的专家; (3)LMIC联合导师，来自尼日利亚大学教学医院[UNTH]的Tonia Onyeka博士， 在PC研究和实践;（4）LMIC同行导师，来自翻译中心的John Olawepo博士， 实施研究[CTAIR]，他是卫生系统整合方面的专家。我的导师团队 支持我的能力建设和研究项目，其中包括一项试点研究，以探讨可行性， 为促进感染艾滋病毒的妇女的福祉而采用的文化适应性和综合性预防犯罪一揽子措施的可接受性 （WLHIV）和宫颈癌。我的具体目标是：（1）共同创造和发展可行的，文化适应， 和可持续的个人电脑服务包与WLHIV和宫颈癌从NISA-MIRC。我们将调整核心 国家综合癌症网络（NCCN）指南中推荐的PC服务元素， 成熟的混合方法;和（2）试点调整后的多组分PC包以确定 在两个NISA-MIRC设施的可行性和可接受性。在这一年的行政奖励，我的尼日利亚- 美国的导师、共同导师和同行导师将在各自领域提供额外的培训和指导 专业知识，包括实施科学，基于社区的参与性研究，PC和卫生系统 一体化

PROJECT SUMMARY My proposal is a submission in response to the Notice of Special Interest (NOSI) identified as NOT-CA-23-038. I am an Assistant Professor of Medical Sociology and Anthropology and a Research Fellow at the Center for Translation and Implementation Science (CTAIR) at the University of Nigeria, Nsukka. My research focuses on palliative care (PC), cancer and women’s health in low- and middle-income countries (LMICs). This administrative supplement mentor award will provide me with the support needed to achieve the following 3 key career development objectives for research in LMIC settings: (1) Sharpen my skills in community based participatory research, stakeholder’s engagement and program integration especially in PC clinical settings; (2) Acquire in-depth knowledge of implementation frameworks and methods to help close the gap between implementation science and implementation practice; (3) Acquire skills and content expertise in PC research. I will conduct research and work with my mentors for a minimum of 40% of my time within the Nigerian Implementation Science Alliance-Model Innovation and Research Centers (NISA-MIRCs), a practice-based research network across the six geographical regions in Nigeria. To accomplish these objectives, I have put together a mentoring team including: (1) a US Primary Mentor, Prof. Gregory Aarons from University of California, San Diego who is an expert in Implementation Science; (2) a LMIC Primary Mentor, Prof. Echezona Ezeanolue from the University of Nigeria, who is an expert in community-based participatory research and clinical research; (3) a LMIC Co-Mentor, Dr Tonia Onyeka from University of Nigeria Teaching Hospital [UNTH], who is an expert in PC research and practice; (4) a LMIC Peer-Mentor, Dr John Olawepo from Center of Translation and Implementation Research [CTAIR], who is an expert in health systems integration. My team of mentors will support my capacity building and research project, which includes a pilot study to explore the feasibility and acceptability of a culturally adapted and integrated PC package to promote wellbeing of women living with HIV (WLHIV) and cervical cancers. My specific aims are to: (1) Co-create and develop feasible, culturally adapted, and sustainable PC service package with WLHIV and cervical cancer from the NISA-MIRCs. We will adapt core elements of PC services recommended in the National Comprehensive Cancer Network (NCCN) guideline using well-established mixed method approaches; and (2) Pilot the adapted multicomponent PC package to determine feasibility and acceptability at two NISA-MIRCs facilities. During the year of this administrative award, my Nigeria- and US-based mentors, co-mentor, and peer-mentor will provide additional training and guidance in their areas of expertise including implementation science, community based participatory research, PC, and health systems integration.