Developing climate cohorts to understand health associations and resilience and susceptibility factors in Ghana

项目总结 过去半个世纪取得的全球卫生成果正面临被气候变化侵蚀的风险，气候变化 不成比例地影响低收入和中等收入国家(LMIC)。在小岛屿发展中国家，科学和政策规划 将气候相容战略纳入卫生部门等气候敏感领域的能力是 由于缺乏对本国当地气候敏感性的经验性估计，严重阻碍了这一进程 而且，对政策至关重要的是，了解特定人群的复原力和易感因素。的确， 最近的气候敏感性依赖于具有大规模行政数据的LMIC的数据(巴西，中国)作为一个 非洲大陆的代理人。尽管有这个主要的限制，这些数据表明温度的影响 在没有可用数据的地区，易感人群的死亡率将增加约50%，例如 非洲。我们建议在加纳通过有指导的研究和发展气候科学专业知识 两组强化的“气候队列”。我们将利用特征良好、现存的随机化的加纳 空气污染与健康研究，以考察气候暴露对母婴健康的影响。 我们还将开始与金坦波卫生和人口监测系统(KHDSS)合作，准备 为未来的气候工作利用这一丰富的数据资源。这项工作将开始提炼气候健康敏感性。 估计，提供对复原力和易感因素的关键见解，并填补急需的政策和 与实践相关的证据差距。该项目的一个长期目标是为继续 加纳的气候科学，以及其他有类似现有队列的非洲国家的模式，共同 促进非洲大陆的气候研究。

Project summary Global health gains achieved over the past half century are at risk of being eroded by climate change, which disproportionately affects low- and middle-income countries (LMICs). In LMICs, scientific and policy planning capacity to incorporate climate compatible strategies into climate sensitive areas like the health sector is severely hampered by the lack of empirically derived estimates of local climate sensitivities from their countries and, critical for policy, an understanding of population-specific resilience and susceptibility factors. Indeed, recent climate sensitivities relied on data from LMICs with large scale administrative data (Brazil, China) as a proxy for the African continent. Despite this major limitation, these data suggest that the effect of temperature on mortality in susceptible groups will be ~50% larger in regions for which there is no available data, such as Africa. We propose to build climate science expertise in Ghana by mentored research and the development of two reinforcing sets of “climate cohorts.” We will leverage the well-characterized, extant Ghana Randomized Air Pollution and Health Study to examine associations between climatic exposures on maternal-child health. We will also begin work with the Kintampo Health and Demographic Surveillance System (KHDSS) to prepare for future climate work leveraging this rich data resource. This work will begin to refine climate health sensitivity estimates, provide key insights into resilience and susceptibility factors, and fill urgently-needed policy and practice-relevant evidence gaps. A long-term goal of this project is to provide a framework for continued climate science in Ghana and a model for other African countries with similar extant cohorts, to collectively catalyze climate research on the African continent.