Mechanisms of central nervous system disease induced by dysregulated interferon signalling

干扰素信号传导失调诱发中枢神经系统疾病的机制

• 批准号: nhmrc : 512407
• 负责人: Prof Iain Campbell
• 金额: $ 41.22万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-central-nervous-interferon-signalling/100619
• 关键词: Mechanisms; central; nervous; system; disease

Interferons are proteins that on one hand have been found to protect cells against infectious agents such as viruses but on the other can cause injury and disease in the brain. In this project the way in which interferons affect the brain to bring about these outcomes will be studied. The results of this work will advance our understanding of how interferons function and may lead to better approaches for combating immune and infectious diseases of the nervous system.

干扰素是一种蛋白质，一方面可以保护细胞免受病毒等感染，另一方面可以导致大脑损伤和疾病。在这个项目中，干扰素影响大脑产生这些结果的方式将被研究。这项工作的结果将促进我们对干扰素功能的理解，并可能导致更好的方法来对抗神经系统的免疫和传染性疾病。