Mechanisms of central nervous system disease induced by dysregulated interferon signalling

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Interferons are proteins that on one hand have been found to protect cells against infectious agents such as viruses but on the other can cause injury and disease in the brain. In this project the way in which interferons affect the brain to bring about these outcomes will be studied. The results of this work will advance our understanding of how interferons function and may lead to better approaches for combating immune and infectious diseases of the nervous system.