Regional Biocontainment Laboratory (RBL) for Region V

描述（由申请人提供）：里基茨（区域生物防护）实验室将在伊利诺伊州芝加哥附近的阿贡国家实验室从能源部租用的安全区域内建造。它将服务于中西部RCE（区域卓越中心）的研究、转化研究、研究培训、服务和应急响应功能。中西部RCE包括来自阿贡国家实验室、巴特尔纪念研究所、伊利诺伊理工学院、梅奥诊所、威斯康星医学院、密歇根州立大学、西北大学、圣母大学、普渡大学、芝加哥大学、伊利诺伊大学厄巴纳-香槟分校、密歇根大学和威斯康星大学的V区科学家。来自100多位科学家的智力贡献产生了25个跨学科、跨机构的研究项目，这些项目由竞争性同行评审选出。这些项目的重点是研究美国疾病控制与预防中心（CDC）的A类精选药物，以开发新的治疗方法、疫苗和诊断设备。审查机制将为NIAID支持的非rce科学家提供访问，包括专有研究。应急计划提供培训，并在必要时对应急人员作出全面承诺。里基茨实验室将拥有54,100平方英尺（27,500净平方英尺），其中8,900平方英尺的BSL-2/BSL-3分子实验室空间和13,300平方英尺的BSL-2/BSL-3动物研究实验室。它将有能力同时研究四种或更多不同的选择剂A类病原体，由五名主要研究人员和35名工作人员组成的研究小组，总容量约为30,000只小鼠或其他实验动物。

DESCRIPTION (provided by applicant): The Ricketts (Regional Biocontainment) Laboratory would be constructed in a secure area leased from the Department of Energy at Argonne National Laboratory near Chicago, Illinois. It would serve the research, translational research, research training, service, and emergency response functions of the Midwest RCE (Regional Center of Excellence). The Midwestern RCE includes Region V scientists from Argonne National Laboratory, Battelle Memorial Institute, Illinois Institute of Technology, Mayo Clinic, Medical College of Wisconsin, Michigan State University, Northwestern University, Notre Dame University, Purdue University, University of Chicago, University of Illinois at Urbana-Champaign, University of Michigan, and University of Wisconsin. Intellectual contributions from over 100 scientists produced twenty-five inter-disciplinary, inter-institutional research programs selected by competitive peer review. The programs focus on studying CDC Category A Select Agents to develop new therapeutics, vaccines and diagnostic devices. Review mechanisms will provide access for NIAID supported non-RCE scientists, including proprietary research. An emergency response plan provides training and, when necessary complete commitment to emergency responders. The Ricketts Laboratory would have 54,100 square feet (27,500 net square feet (NSF)), with 8,900 NSF of BSL-2/BSL-3 molecular laboratory space and 13,300 NSF of BSL-2/BSL-3 animal research laboratories. It would have the capacity for simultaneous study of four or more different Select Agent Category A pathogens, by the research groups of five principal investigators and thirty-five staff scientists, with a total holding capacity for about 30,000 mice or other experimental animals.